Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Annika Friberg"'
Autor:
Leila Etemadi, Mohsin Mohammed, Palmi Thor Thorbergsson, Joakim Ekstrand, Annika Friberg, Marcus Granmo, Lina M E Pettersson, Jens Schouenborg
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155109 (2016)
Neural interfaces which allow long-term recordings in deep brain structures in awake freely moving animals have the potential of becoming highly valuable tools in neuroscience. However, the recording quality usually deteriorates over time, probably a
Externí odkaz:
https://doaj.org/article/5120adeef0d04b1f89130f0f9bdf2108
Autor:
Marcus Malo, Krystle da Silva Andersson, Morten Grøtli, Annika Friberg, Christine Dyrager, Kristian Dahlén, Tina Seifert, Erik A.A. Wallén, Kristina Luthman, Nils Pemberton, Maria Fridén-Saxin
Publikováno v:
European journal of medicinal chemistry. 114
A scaffold approach has been used to develop somatostatin β-turn mimetics based on chroman-4-one and chromone ring systems. Such derivatives could adopt conformations resembling type II or type II' β-turns. Side chain equivalents of the crucial Trp
Autor:
Kristian Dahlén, Annika Friberg, Erik A.A. Wallén, Morten Grøtli, Kristina Luthman, Christine Dyrager, Malin Wickström, Joachim Gullbo, Maria Fridén-Saxin
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2659-2665
A series of dihalogenated chalcones and structurally related dienones were synthesized and evaluated for their antiproliferative activity in 10 different cancer cell lines and for their effect on microtubule assembly. All compounds showed cytotoxic a
Autor:
Krystle da Silva Andersson, Morten Grøtli, Christine Dyrager, Annika Friberg, Nils Pemberton, Kristina Luthman, Maria Fridén-Saxin
Publikováno v:
The Journal of Organic Chemistry. 74:2755-2759
A base-promoted condensation between 2-hydroxyacetophenones and aliphatic aldehydes has been studied. The reaction has been optimized to afford 2-alkyl-substituted 4-chromanones in an efficient manner using microwave heating. Performing the reaction
Publikováno v:
Tetrahedron: Asymmetry. 19:1765-1777
An improved synthetic route to the bicyclo[2.2.2]octane-2,6-diol ligands (2,6-BODOLS) allowed an increased structural variation of the ligand side-arm. The addition of aromatic or vinylic Grignard reagents to hydroxyketone 1 was highly selective and
Publikováno v:
Tetrahedron: Asymmetry. 19:1476-1483
Chiral bicyclic diols based on bicyclo[2.2.2]octane and bicyclo[2.2.1]heptane have been synthesized and their catalytic capacity in the asymmetric diethylzinc addition to benzaldehyde compared with those described for previously synthesized 2,6-bicyc
Publikováno v:
Tetrahedron: Asymmetry. 18:885-891
The synthesis and application of chiral carbocyclic cleft molecules derived from 2,3:6,7-dibenzobicyclo[3.3.1]nona-2,6-diene-4,8-diene in the hetero-Diels-Alder reaction of benzaldehydes and aminodiene 14 is presented. Catalysis by single hydrogen-bo
Publikováno v:
International journal of pharmaceutics. 499(1-2)
Polymeric nanoparticles is an established and efficient means to achieve controlled release of drugs. Incorporation of minocycline, an antibiotic with anti-inflammatory and neuroprotective properties, into biodegradable nanoparticles may therefore pr
Autor:
Melanie Dietz, Mikael Katz, Magnus Widegren, Torbjörn Frejd, Marie-Francoise Gorwa-Grauslund, Bärbel Hahn-Hägerdal, Annika Friberg
Publikováno v:
Synthesis. 2006:3527-3530
The cyclisation conditions for the formation of bicyclo[2.2.2]octan-2,6-di one (1) from 3-substituted cyclohexanones 2 and 3 have been re-investigated. Use of a medium consisting of isobutyric anhydride and trifluoroacetic acid resulted in a simplifi
Publikováno v:
Chirality. 16:614-624
Two pairs of chiral stationary phases (CSPs) with different C-2-symmetric central parts were prepared and evaluated by chromatography of a series of structurally different racemates. Within each pair, the selectors on which the CSPs are based had dif