Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Annika Dalheim"'
Autor:
Jessica Fleser, Bernard A. Fox, Annika Dalheim, David C. Murray, Chris Fountain, Constantine Godellas, Tamson V. Moore, Brendan D. Curti, Joseph I. Clark, Jodi Speiser, Siao Yi Wang, Michael I. Nishimura, Mallory Thomas, Matthew DeJong, Courtney Regan Wagner, Tarsem Moudgil, Gina Scurti, Kelli A. Hutchens
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss, Pp 352-363 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
T cells that are gene-modified with tumor-specific T cell receptors are a promising treatment for metastatic melanoma patients. In a clinical trial, we treated seven metastatic melanoma patients with autologous T cells transduced to express a tyrosin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Adoptive T cell therapy with T cell receptor (TCR)-modified T cells has shown promise in treating metastatic melanoma and other malignancies. However, studies are needed to improve the efficacy and durability of responses of TCR-modified T cells. Sta
Autor:
Vamsi K. Gangaraju, Shikhar Mehrotra, Besim Ogretmen, Gary Hardiman, Annika Dalheim, Nilanjana Maulik, Supinya Iamsawat, Paramita Chakraborty, Elizabeth G. Hill, Shilpak Chatterjee, Pravin Kesarwani, Gina Scurti, Shanmugam Panneer Selvam, Hung Nguyen, Xue-Zhong Yu, Nancy Klauber-DeMore, Krishnamurthy Thyagarajan, Mark P. Rubinstein, Patrick Nasarre, Lauren E. Ball, Michael I. Nishimura
Publikováno v:
J Biol Chem
Adoptive transfer of tumor epitope–reactive T cells has emerged as a promising strategy to control tumor growth. However, chronically-stimulated T cells expanded for adoptive cell transfer are susceptible to cell death in an oxidative tumor microen
Autor:
Eva Tamayo-Torres, Stephen L. Ollosi, Ines Pulido, Juan Carlos García-Cañaveras, Adrián López, Marta Benet, Juan B. Salom, Jeffrey A. Borgia, Oscar Juan, Javier Alcácer Fernández-Coronado, Julian Carretero, Javier Alcácer, Maria L. Rodriguez, Lourdes Chuliá-Peris, Simon Kaja, Fatima Al-Shahrour, Jeffrey H. Becker, Margaret Soucheray, Wei Qiu, Alicia Aliena-Valero, Takeshi Shimamura, Sandra Alandes, Agustín Lahoz, Annika Dalheim, Salvador Aparisi, Michael I. Nishimura
Publikováno v:
Cancer research, vol 80, iss 19
CANCER RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
CANCER RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Progression on therapy in non-small cell lung carcinoma (NSCLC) is often evaluated radiographically, however, image-based evaluation of said therapies may not distinguish disease progression due to intrinsic tumor drug resistance or inefficient tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb092164a17e01f44fa5a1a12669a1e
https://escholarship.org/uc/item/14v7f21g
https://escholarship.org/uc/item/14v7f21g
Autor:
Jeremiah J. Zartman, Simon Kaja, Saverio Gentile, Miranda Burnette, Claire M. Wells, Michael I. Nishimura, Glen L. Niebur, Ricardo Romero-Moreno, Eun Kyoung Breuer, Loredana Campo, Daniela Fukushiro-Lopes, Kimberly J. Curtis, Laurie E. Littlepage, Kent Hoskins, Annika Dalheim
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 3, Pp 1-15 (2019)
Cell Death and Disease, Vol 10, Iss 3, Pp 1-15 (2019)
Potassium ion channels are critical in the regulation of cell motility. The acquisition of cell motility is an essential parameter of cancer metastasis. However, the role of K+ channels in cancer metastasis has been poorly studied. High expression of
Autor:
Khayrun Nahar, Guillem Genové, Annika Keller, Michael Vanlandewijck, Bàrbara Laviña, Maarja Andaloussi Mäe, Jennifer J. Hofmann, Liqun He, Christer Betsholtz, Giacomo Bertuzzi, Elisabeth Raschperger, Tian Li, Annika Dalheim
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Diabetes mellitus is associated with cognitive impairment and various central nervous system pathologies such as stroke, vascular dementia, or Alzheimer’s disease. The exact pathophysiology of these conditions is poorly understood. Recent reports s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd25babaf3b654cd9bc8b5ab39804ab8
https://www.zora.uzh.ch/id/eprint/160410/
https://www.zora.uzh.ch/id/eprint/160410/
Autor:
Annika Dalheim, Stephen L. Ollosi, Takeshi Shimamura, Ines Pulido, Jeffrey H. Becker, Michael Nishimura, Fatima Al-Shahrour, Julian Carretero, Simon Kaja, Margaret Soucheray, Wei Qui
Publikováno v:
Cancer Research. 78:20-20
Despite recent advances in the treatment of NSCLC targeting of EGFR kinase domain mutations with tyrosine kinase inhibitors (TKIs), work needs to be done to reduce morbidity and improve survival for NSCLC patients. In NSCLC, tumor angiogenesis has be
Publikováno v:
Journal of Clinical Oncology. 35:e14552-e14552
e14552 Background: Metastatic melanoma remains a fatal disease as many patients fail to respond to novel therapies. Presently, we have an ongoing trial utilizing T cell receptor (TCR)-modified cells reactive to the melanoma antigen, tyrosinase, for t