Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annika Björe"'
Autor:
Annika Åstrand, Monika Sundqvist, Maria Thorstensson, Tomas Fex, Andreas Nordin, Ahlke Hayen, Annika Björe, Ulrik Gran, Christina Olsson, Johan Sundell, Elin Forsström, Emma Lindhardt, Jonas Boström, Gunilla Linhardt, Teresa Collins, Boel Löfberg, Fanyi Jiang, Roine I. Olsson, Ingemar Jacobson, Anna Öhrn, Karolina Aplander, Olle Hidestål, Jonna Gyll
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:706-710
Diphenylphosphinic amides and diphenylphosphine oxides have been synthesized and tested as inhibitors of the Kv1.5 potassium ion channel as a possible treatment for atrial fibrillation. In vitro structure-activity relationships are discussed and seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692644b9777064b4390bd126a7b17fa2
https://doi.org/10.1016/j.bmcl.2012.11.098
https://doi.org/10.1016/j.bmcl.2012.11.098
Autor:
Sara Holmqvist, Thomas Elebring, Jane E. Moore, Magnus Johansson, Fritiof Ponten, Shalini Andersson, Petra Johannesson, Steve Chapman, Craig S. Donald, Paul Robert Owen Whittamore, Paul Schofield, Jonas A. Pettersson, Robert D. M. Davies, Sue Bowker, Craig Johnstone, Malin Lemurell, Bryan J. Egner, Paul D. Kemmitt, Tord Inghardt, Jan Kihlberg, Pernilla Korsgren, Nidhal Selmi, Annika Björe, Helen Pointon, Alan Armstrong
Publikováno v:
Drug Discovery Today. 14:598-604
The pharmaceutical industry, particularly the small molecule domain, faces unprecedented challenges of escalating costs, high attrition as well as increasing competitive pressure from other companies and from new treatment modes such as biological pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412cd92df3b770742b045849e931d545
https://doi.org/10.1016/j.drudis.2009.03.005
https://doi.org/10.1016/j.drudis.2009.03.005
Autor:
Annika Åstrand, Anna Rönnborg, Emma Lindhardt, Ulrik Gran, Gert Strandlund, Hans Emtenäs, Zhong-Qing Yuan, Jonas Boström, Johan Sundell, Jonna Gyll, Ågot Högberg, Boel Löfberg, Tommy Iliefski, Roine I. Olsson, Birgit Andersson, Olle Hidestål, Tor Svensson, Ingemar Jacobson, Elin Forsström, Frida Persson, Christina Olsson, Annika Björe, Gunilla Linhardt, Öjvind Davidsson, Ola Fjellström, Jesper Malmberg
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(5)
A series of lactam sulfonamides has been discovered and optimized as inhibitors of the Kv1.5 potassium ion channel for treatment of atrial fibrillation. In vitro structure–activity relationships from lead structure C to optimized structure 3y are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71012effbd3cf129aff4e8df9e21b478
https://pubmed.ncbi.nlm.nih.gov/24513046
https://pubmed.ncbi.nlm.nih.gov/24513046