Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Annika, Niehrs"'
Autor:
Annerose E. Ziegler, Pia Fittje, Luisa M. Müller, Annika E. Ahrenstorf, Kerri Hagemann, Sven H. Hagen, Leonard U. Hess, Annika Niehrs, Tobias Poch, Gevitha Ravichandran, Sebastian M. Löbl, Benedetta Padoan, Sébastien Brias, Jana Hennesen, Myrtille Richard, Laura Richert, Sven Peine, Karl J. Oldhafer, Lutz Fischer, Christoph Schramm, Glòria Martrus, Madeleine J. Bunders, Marcus Altfeld, Sebastian Lunemann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell activity. The co-inhibitory receptor TIGIT decreases NK cell cytotoxicity and is involved in NK cel
Externí odkaz:
https://doaj.org/article/8eaeca7d25fc4207b64b0945cfe316a2
Autor:
Sarah Vollmers, Annabelle Lobermeyer, Annika Niehrs, Pia Fittje, Daniela Indenbirken, Jacqueline Nakel, Sanamjeet Virdi, Sebastien Brias, Timo Trenkner, Gabriel Sauer, Sven Peine, Georg M.N. Behrens, Clara Lehmann, Anja Meurer, Ramona Pauli, Nils Postel, Julia Roider, Stefan Scholten, Christoph D. Spinner, Christoph Stephan, Eva Wolf, Christoph Wyen, Laura Richert, Paul J. Norman, Jürgen Sauter, Alexander H. Schmidt, Angelique Hoelzemer, Marcus Altfeld, Christian Körner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
NK cells play a pivotal role in viral immunity, utilizing a large array of activating and inhibitory receptors to identify and eliminate virus-infected cells. Killer-cell immunoglobulin-like receptors (KIRs) represent a highly polymorphic receptor fa
Externí odkaz:
https://doaj.org/article/59182d0cd5c0463dbd87de55889bd8bc
Autor:
Pia Fittje, Angelique Hœlzemer, Wilfredo F Garcia-Beltran, Sarah Vollmers, Annika Niehrs, Kerri Hagemann, Glòria Martrus, Christian Körner, Frank Kirchhoff, Daniel Sauter, Marcus Altfeld
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010572 (2022)
Antiviral NK cell activity is regulated through the interaction of activating and inhibitory NK cell receptors with their ligands on infected cells. HLA class I molecules serve as ligands for most killer cell immunoglobulin-like receptors (KIRs), but
Externí odkaz:
https://doaj.org/article/1d76922e6a454e039e1ea963ed8d22ed
Autor:
Annika Niehrs, Marcus Altfeld
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Natural Killer (NK) cells were initially described as part of the innate immune system and characterized by their ability to lyse malignant and virus-infected cells. The cytolytic function of NK cells is tightly controlled by activating and inhibitor
Externí odkaz:
https://doaj.org/article/f783bca2ba7948ee81733e5d95c65eb9
Autor:
Glòria Martrus, Hanna Goebels, Annika E. Langeneckert, Janine Kah, Felix Flomm, Annerose E. Ziegler, Annika Niehrs, Sebastian M. Löbl, Kristina Russu, Leonard U. Hess, Wilhelm Salzberger, Tobias Poch, Björn Nashan, Christoph Schramm, Karl J. Oldhafer, Maura Dandri, Martina Koch, Sebastian Lunemann, Marcus Altfeld
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Macrophages play central roles in inflammatory reactions and initiation of immune responses during infections. More than 80% of total tissue macrophages are described to be located in the liver as liver-resident macrophages, also named Kupffer cells
Externí odkaz:
https://doaj.org/article/bbcf187bfaf54455a652f815897327c5
Autor:
Jan P. Bremer, Martin E. Baumdick, Marius S. Knorr, Lucy H.M. Wegner, Jasmin Wesche, Ana Jordan-Paiz, Johannes M. Jung, Andrew J. Highton, Julia Jäger, Ole Hinrichs, Sebastien Brias, Jennifer Niersch, Luisa Müller, Renée R.C.E. Schreurs, Tobias Koyro, Sebastian Löbl, Leonore Mensching, Leonie Konczalla, Annika Niehrs, Florian W. R. Vondran, Christoph Schramm, Angelique Hölzemer, Karl Oldhafer, Ingo Königs, Stefan Kluge, Daniel Perez, Konrad Reinshagen, Steven T. Pals, Nicola Gagliani, Sander P. Joosten, Maya Topf, Marcus Altfeld, Madeleine J. Bunders
Organoids have emerged as a powerful technology to investigate human development, model diseases and for drug discovery. However, analysis tools to rapidly and reproducibly quantify organoid parameters from microscopy images are lacking. We developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13521250821e90d01118ad2f34ec3450
https://doi.org/10.1101/2022.09.06.506648
https://doi.org/10.1101/2022.09.06.506648
Autor:
Johannes Höfle, Timo Trenkner, Nadja Kleist, Vera Schwane, Sarah Vollmers, Bryan Barcelona, Annika Niehrs, Pia Fittje, Van Hung Huynh‐Tran, Jürgen Sauter, Alexander H Schmidt, Sven Peine, Angelique Hoelzemer, Laura Richert, Marcus Altfeld, Christian Körner
Publikováno v:
EMBO reports. 23(8)
NK cells utilize a large array of receptors to screen their surroundings for aberrant or virus-infected cells. Given the vast diversity of receptors expressed on NK cells we seek to identify receptors involved in the recognition of HIV-1-infected cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ee57111a1758914f1665f2b0fca817
https://pubmed.ncbi.nlm.nih.gov/35758160
https://pubmed.ncbi.nlm.nih.gov/35758160
Autor:
Pia Fittje, Angelique Hœlzemer, Wilfredo F. Garcia-Beltran, Sarah Vollmers, Annika Niehrs, Kerri Hagemann, Glòria Martrus, Christian Körner, Frank Kirchhoff, Daniel Sauter, Marcus Altfeld
Publikováno v:
PLoS pathogens. 18(6)
Antiviral NK cell activity is regulated through the interaction of activating and inhibitory NK cell receptors with their ligands on infected cells. HLA class I molecules serve as ligands for most killer cell immunoglobulin-like receptors (KIRs), but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4d13c035b5c3a33af0c8c0164b6905
https://pubmed.ncbi.nlm.nih.gov/35749424
https://pubmed.ncbi.nlm.nih.gov/35749424
Autor:
Kristina Russu, Christian Körner, Mirjam E Belderbos, Kimberly J. Möller, Suze A. Jansen, Mareike Ohms, Annika Niehrs, Ingo Königs, Anja Ehrhardt, Johannes M. Jung, Lucy Wegner, Martin E. Baumdick, Helga Hofmann-Sieber, Thomas Dobner, Marc Lütgehetmann, Madeleine J. Bunders, Wilhelm Ching, Marcus Altfeld, Angelique Hölzemer, Kevin Duisters, Caroline A. Lindemans, Sven Peine, Tobias Koyro, Wenli Zhang, Daniel Perez, Jens B. Bosse, Eric Spierings, Konrad Reinshagen
Publikováno v:
Science immunology. 6(63)
Human adenoviruses (HAdVs) are a major cause for disease in children, in particular after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Currently, effective therapies for HAdV infections in immunocompromised hosts are lacking. To de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8255e871e43f13b7c8ccb7a7913153dd
https://pubmed.ncbi.nlm.nih.gov/34533978
https://pubmed.ncbi.nlm.nih.gov/34533978
Autor:
Annika, Niehrs, Marcus, Altfeld
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Natural Killer (NK) cells were initially described as part of the innate immune system and characterized by their ability to lyse malignant and virus-infected cells. The cytolytic function of NK cells is tightly controlled by activating and inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a648d6a3b1b1175a74f5c19e5c7086f
https://pubmed.ncbi.nlm.nih.gov/32133304
https://pubmed.ncbi.nlm.nih.gov/32133304