Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anniesha Hack"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67348 (2013)
An unconventional interaction between SPCA2, an isoform of the Golgi secretory pathway Ca(2+)-ATPase, and the Ca(2+) influx channel Orai1, has previously been shown to contribute to elevated Ca(2+) influx in breast cancer derived cells. In order to i
Externí odkaz:
https://doaj.org/article/b97c1b303e6d4c74b5a9e7805f9e1dbf
Autor:
Rao Prabhala, Diego Hernandez Rodriguez, Kenneth C. Anderson, Marc Credi, Lawrence Rispoli, Omar Nadeem, Jacob P. Laubach, Sarah Nikiforow, Kit L. Shaw, Nikhil C. Munshi, Yohei Arihara, Soudeh Ansari, Jerome Ritz, Alejandro Alonso, Serena De Vita, Shuntaro Ikegawa, David Pearson, Clifton C. Mo, Jennifer Marie Mataraza, Anniesha Hack, Adam S. Sperling, Dexiu Bu, Heather Daley, Louise Treanor, David Quinn
Publikováno v:
Blood. 138:3864-3864
Background: Chimeric antigen receptor (CAR)-T cells are highly effective in patients (pts) with multiple myeloma (MM), but duration of response can be limited, and pts with rapidly progressing disease require a fast and reliable CAR-T cell manufactur
Autor:
José P. Llongueras, Vivian Capilla-Gonzalez, Anniesha Hack, Hugo Guerrero-Cazares, Alfredo Quiñones-Hinojosa, Kalyan C. Kondapalli, Hari Prasad, Rajini Rao, Christopher Smith
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature communications
instname
Nature communications
Epidermal growth factor receptor (EGFR) signalling is a potent driver of glioblastoma, a malignant and lethal form of brain cancer. Disappointingly, inhibitors targeting receptor tyrosine kinase activity are not clinically effective and EGFR persists
Autor:
Hugo Guerrero-Cazares, José P. Llongueras, Christopher Smith, Kalyan C. Kondapalli, Vivian Capilla-Gonzalez, Anniesha Hack, Alfredo Quiñones-Hinojosa, Rajini Rao
Publikováno v:
The FASEB Journal. 28
Na+(K+)/H+ Exchangers (NHEs) are a large family of transport proteins that conduct electroneutral countertransport of cations with protons across lipid bilayers. A newly discovered Na+/H+ Exchanger...
Publikováno v:
Nature communications
Summary NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologs in yeast and bacteria. Rare, missense substitutions in NHE9 are genetically linked with autism, but have not been functionally evaluated. Here we use evolutionary conservat
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67348 (2013)
PLoS ONE
PLoS ONE
An unconventional interaction between SPCA2, an isoform of the Golgi secretory pathway Ca(2+)-ATPase, and the Ca(2+) influx channel Orai1, has previously been shown to contribute to elevated Ca(2+) influx in breast cancer derived cells. In order to i
Autor:
Isabelle Riviere, Jinrong Qu, Jolanta Stefanski, Oriana Borquez-Ojeda, Anniesha Hack, Xiuyan Wang
Publikováno v:
The Journal of Immunology. 196:214.25-214.25
Adoptive transfer of chimeric antigen receptor (CAR) engineered T cells is a promising strategy to treat patients with cancer. Apheresis products are commonly used as starting material for large-scale T cell selection using CD3/28 magnetic beads. At
Autor:
Jinrong Qu, Isabelle Riviere, Fang Du, Oriana Borquez-Ojeda, Xiuyan Wang, Jolanta Stefanski, Qing He, Michel Sadelain, Teresa Wasielewska, Anniesha Hack
Publikováno v:
Molecular Therapy. 24:S182
Adoptive transfer of chimeric antigen receptor (CAR) engineered T cells is a promising emerging strategy to treat cancer patients. Large-scale manufacturing of cGMP-grade CAR T cells using patient T cells selected and activated by CTS™ Dynabeads®
Publikováno v:
The FASEB Journal. 26
Publikováno v:
Biophysical Journal. 100(3):247a-248a
A number of neurological disorders including autism, have been linked to mutations in a subgroup of intracellular Na+(K+)/H+ exchangers, which include NHE6 and NHE9 that localize to recycling and late endosomes respectively. These are thought to medi