Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Annie Yang Weaver"'
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Abstract 212: CD166-DM4 probody drug conjugate (CX-2009) treatment of 198 patient-derived xenograft models (PDX) in a mouse clinical trial format
Autor: Joel Shen, Jennifer Richardson, Bob Y. Liu, Siew Schleyer, Annie Yang Weaver, Matthias Will, Sreeni Yalamanchili, Michael P. Kavanaugh, Marcia Belvin, Judi Gordon, Luc Desnoyer, Mark Stroh
Publikováno v: Cancer Research. 79:212-212
Ideal targets for antibody drug conjugates (ADC) are highly and homogeneously expressed on tumor cells in a wide variety of tumor types and in a high proportion of patients. Such targets should also be efficient cellular internalizers and have limite
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f82c61f3382dd74a740c88046562950
https://doi.org/10.1158/1538-7445.am2019-212
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3
Abstract 2975: Development of a probody drug conjugate (PDC) targeting CD71 for the treatment of solid tumors and lymphomas
Autor: Luc Desnoyers, Yuanhui Huang, Shouchun Liu, Annie Yang Weaver, Shweta Singh, Linnea Diep, Kim Tipton, Jonathan Alexander Terrett, Clayton White, Jennifer Richardson, Amy DuPage, W. Michael Kavanaugh, Michael Krimm, Jason Gary Sagert
Publikováno v: Cancer Research. 76:2975-2975
The targets of Antibody Drug Conjugates (ADCs) have typically been selected by identifying transmembrane antigens that are highly expressed in tumors but are low or absent in normal tissues. The number of potential ADC targets meeting these requireme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a77330f2b46f55a1d1e023052ceb462
https://doi.org/10.1158/1538-7445.am2016-2975
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