Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annie X. Y. Mo"'
Publikováno v:
The Journal of Immunology. 164:4003-4010
The proteasome has been shown to make the proper C-terminal cleavage for the generation of several immunodominant class I-presented peptides whereas aminopeptidases generate their proper N termini. In this study, we show that these two distinct prote
Autor:
Wanyong Zeng, Ian A. York, Annie X. Y. Mo, Kristen Lemerise, Kenneth L. Rock, Carmela R. Abraham, Tomo Saric, Yuelei Shen, Alfred L. Goldberg
Publikováno v:
Immunity. (3):429-440
Most antigenic peptides presented on MHC class I molecules are generated by proteasomes during protein breakdown. It is unknown whether these peptides are protected from destruction by cytosolic peptidases. In cytosolic extracts, most antigenic pepti
Publikováno v:
Immunology. Jan2005, Vol. 114 Issue 1, p141-154. 14p.