Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Annie W. Shieh"'
Autor:
Jose L. Ortiz-Vitali, Jianbo Wu, Nasa Xu, Annie W. Shieh, Nima Niknejad, Megumi Takeuchi, Carmen Paradas, Chunru Lin, Hamed Jafar-Nejad, Robert S. Haltiwanger, Sidney H. Wang, Radbod Darabi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 683-697 (2023)
Autosomal recessive limb-girdle muscular dystrophy 21 (LGMDR21) is caused by pathogenic variants in protein O-glucosyltransferase 1 (POGLUT1), which is responsible for O-glucosylation of specific epidermal growth factor (EGF) repeats found in ∼50 m
Externí odkaz:
https://doaj.org/article/890197d4a6154dcbb8fa3f4e093f2cfc
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/f92a626170a44b88bc5a55bd1d3e82c4
Autor:
Julien Bryois, Melanie E. Garrett, Lingyun Song, Alexias Safi, Paola Giusti-Rodriguez, Graham D. Johnson, Annie W. Shieh, Alfonso Buil, John F. Fullard, Panos Roussos, Pamela Sklar, Schahram Akbarian, Vahram Haroutunian, Craig A. Stockmeier, Gregory A. Wray, Kevin P. White, Chunyu Liu, Timothy E. Reddy, Allison Ashley-Koch, Patrick F. Sullivan, Gregory E. Crawford
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Chromatin accessibility may be altered in disease states. Here the authors carry out ATAC-seq on a large number of samples of dorsolateral prefrontal cortex from individuals with schizophrenia, and healthy controls.
Externí odkaz:
https://doaj.org/article/08c8eca6a4644c7a80907c7bfa108e99
Autor:
Jianbo Wu, Nadine Matthias, Jonathan Lo, Jose L. Ortiz-Vitali, Annie W. Shieh, Sidney H. Wang, Radbod Darabi
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1966-1981.e4 (2018)
Summary: Myogenic differentiation of human pluripotent stem cells (hPSCs) has been done by gene overexpression or directed differentiation. However, viral integration, long-term culture, and the presence of unwanted cells are the main obstacles. By u
Externí odkaz:
https://doaj.org/article/76b9f2aea3d04f6b8c2274aac94d96c3
Acute cellular stress is known to induce a global reduction in protein translation through suppression of cap dependent translation. However, selective translation in response to acute stress has been shown to play important roles in regulating the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bffdf9f4cc297b429f0134f59ca47441
https://doi.org/10.1101/2022.05.30.493937
https://doi.org/10.1101/2022.05.30.493937
Autor:
Beisha Tang, Richard F. Kopp, Geoffrey J. Faulkner, Huma Asif, Lixia Qin, Chao Chen, Annie W. Shieh, Zongchang Li, Riyue Bao, Chunling Zhang, Elliot S. Gershon, Gina Giase, Liz Kuney, Shishi Min, Ney Alliey-Rodriguez, Chunyu Liu, David Craig
Publikováno v:
Neurobiol Aging
Somatic mutations arise randomly or are induced by environmental factors, which may increase the risk of Alzheimer's disease (AD). Identifying somatic mutations in sporadic AD (SAD) may provide new insight of the disease. To evaluate the potential co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d56e93b5634e2e73e4c532d0348024
https://europepmc.org/articles/PMC9832973/
https://europepmc.org/articles/PMC9832973/
Autor:
Harish R. Krishnan, Huaibo Zhang, Ying Chen, John Peyton Bohnsack, Annie W. Shieh, Handojo Kusumo, Jenny Drnevich, Chunyu Liu, Dennis R. Grayson, Mark Maienschein-Cline, Subhash C. Pandey
Publikováno v:
Molecular psychiatry. 27(11)
Positive effects of alcohol drinking such as anxiolysis and euphoria appear to be a crucial factor in the initiation and maintenance of alcohol use disorder (AUD). However, the mechanisms that lead from chromatin reorganization to transcriptomic chan
Autor:
Nadine Matthias, Radbod Darabi, Jose L. Ortiz-Vitali, Annie W. Shieh, Jianbo Wu, Jonathan Lo, Sidney H. Wang
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1966-1981.e4 (2018)
Summary: Myogenic differentiation of human pluripotent stem cells (hPSCs) has been done by gene overexpression or directed differentiation. However, viral integration, long-term culture, and the presence of unwanted cells are the main obstacles. By u
Autor:
Quan Wang, Gina Giase, Yi Jiang, Rui Chen, Annie W. Shieh, Kay Grennan, Qiang Wei, Lide Han, Yan Xia, Sihan Liu, Chao Chen, Chunyu Liu, Kevin P. White, Bingshan Li
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 4, p e1007522 (2020)
PLoS Computational Biology, Vol 16, Iss 4, p e1007522 (2020)
Studies of complex disorders benefit from integrative analyses of multiple omics data. Yet, sample mix-ups frequently occur in multi-omics studies, weakening statistical power and risking false findings. Accurately aligning sample information, genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8efe2271691dd1aec5aa543622016f
https://doi.org/10.1101/831537
https://doi.org/10.1101/831537
Autor:
Pamela Sklar, Allison E. Ashley-Koch, Melanie E. Garrett, Alexias Safi, Lingyun Song, Kevin P. White, Craig A. Stockmeier, Alfonso Buil, Julien Bryois, Panos Roussos, Vahram Haroutunian, Annie W. Shieh, Gregory E. Crawford, Graham Johnson, Patrick F. Sullivan, Paola Giusti-Rodríguez, John F. Fullard, Gregory A. Wray, Schahram Akbarian, Timothy E. Reddy, Chunyu Liu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
Schizophrenia genome-wide association studies have identified >150 regions of the genome associated with disease risk, yet there is little evidence that coding mutations contribute to this disorder. To explore the mechanism of non-coding regulatory e