Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annie W. Lau-Kilby"'
Autor:
Gabrielle L. Barry, Alexis J. Balgeman, Thomas C. Friedrich, Nancy J. Sullivan, Annie W. Lau-Kilby, Shelby L. O’Connor, Andrea M. Weiler, Amy L. Ellis-Connell, John R. Mascola, Yan Zhou, Matthew S. Sutton, Rosemarie D. Mason, Scott Hetzel, Kristin K. Biris, Mario Roederer
Publikováno v:
Journal of Virology. 93
We evaluated the contribution of CD8αβ(+) T cells to control of live-attenuated simian immunodeficiency virus (LASIV) replication during chronic infection and subsequent protection from pathogenic SIV challenge. Unlike previous reports with a CD8α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2d48811429189e652b29045f176860
https://doi.org/10.1128/jvi.00537-19
https://doi.org/10.1128/jvi.00537-19
Autor:
Mathilde Turfkruyer, Allison M. W. Malloy, Kimberly Hickey, Ursula J. Buchholz, Lijuan Yang, Annie W. Lau-Kilby, Margaret Kehl
Publikováno v:
Mucosal immunology
Insufficient T-cell responses contribute to the increased burden of viral respiratory disease in infancy. Neonatal dendritic cells (DCs) often provide defective activation of pathogen-specific T cells through mechanisms that are incompletely understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7357b99f18d630a24361560ebbe52239
https://pubmed.ncbi.nlm.nih.gov/31797910
https://pubmed.ncbi.nlm.nih.gov/31797910
Autor:
Yi Liu, Chie Hotta-Iwamura, Yongge Zhao, Kameron B. Rodrigues, Timothy W. Thoner, Juan Quiel, Allison M. W. Malloy, Vipul Bhargava, M. Jubayer Rahman, Kristin V. Tarbell, Annie W. Lau-Kilby, Han-Yu Shih
Publikováno v:
JCI insight. 3(3)
Type I IFN (IFN-I) dysregulation contributes to type 1 diabetes (T1D) development, and although increased IFN-I signals are pathogenic at the initiation of autoimmune diabetes, IFN-I dysregulation at later pathogenic stages more relevant for therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c7486cc869cb5b5f8390074e06a1eb
https://pubmed.ncbi.nlm.nih.gov/29415894
https://pubmed.ncbi.nlm.nih.gov/29415894
Autor:
Barney S. Graham, Tracy J. Ruckwardt, Kaitlyn M. Morabito, Annie W. Lau-Kilby, Allison M. W. Malloy
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(1)
Young infants are generally more susceptible to viral infections and experience more severe disease than do adults. CD8+ T cells are important for viral clearance, and although often ineffective in neonates they can be protective when adequately stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1217296787db9fbcf09cede0fb8c0f05
https://pubmed.ncbi.nlm.nih.gov/27895172
https://pubmed.ncbi.nlm.nih.gov/27895172
Publikováno v:
The Journal of Immunology. 198:203.4-203.4
Dendritic cells (DCs) are among the first to respond to infection, providing the critical link between innate and adaptive immunity. Neonates often have weak innate immune responses that can limit adaptive immunity and contribute to increased suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07eb86637be20db27864383f8bf3ca1f
https://doi.org/10.4049/jimmunol.198.supp.203.4
https://doi.org/10.4049/jimmunol.198.supp.203.4
We have previously shown that interleukin-2 (IL-2) inhibits dendritic cell (DC) development from mouse bone marrow (BM) precursors stimulated with the ligand for FMS-like tyrosine kinase 3 receptor (Flt3L), and have provided evidence that this inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f572729a88f93206679db04c74358f0b
https://europepmc.org/articles/PMC4253512/
https://europepmc.org/articles/PMC4253512/
Autor:
Annie W. Lau-Kilby, Cheng Cheng, Nancy J. Sullivan, Joshua C. Johnson, Clement Asiedu, John C. Trefry, Lingshu Wang, Antonella Folgori, Alfredo Nicosia, Adele Abbate, Kathryn E. Foulds, Richard A. Koup, Fabiana Grazioli, Riccardo Cortese, Gary J. Nabel, Mario Roederer, Daphne A. Stanley, Anna N. Honko, Stefano Colloca, Mitzi M. Donaldson, Lisa E. Hensley, John R. Mascola, Virginia Ammendola
Ebolavirus disease causes high mortality, and the current outbreak has spread unabated through West Africa. Human adenovirus type 5 vectors (rAd5) encoding ebolavirus glycoprotein (GP) generate protective immunity against acute lethal Zaire ebolaviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b613d947b82f4af88261b4c3ff56943b
http://hdl.handle.net/11588/621548
http://hdl.handle.net/11588/621548
Autor:
Annie W. Lau-Kilby, Cosima C. Rieger, Jeffrey D. Price, Gwendoline Rahir, Nicole M. Beauchamp, Yongge Zhao, Kristin V. Tarbell
Publikováno v:
Journal of leukocyte biology. 95(2)
DCs are important mediators of peripheral tolerance for the prevention of autoimmunity. Chimeric αDEC-205 antibodies with attached antigens allow in vivo antigen-specific stimulation of T cells by CD8+ DCs, resulting in tolerance in nonautoimmune mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df861c63c8ddb9a3cdd374a1dcc6940
https://pubmed.ncbi.nlm.nih.gov/24082013
https://pubmed.ncbi.nlm.nih.gov/24082013
Publikováno v:
The Journal of Immunology. 196:78.7-78.7
Dendritic cells (DCs) are critical for the induction of anti-viral CD8+ T cells. Young infants mount poor antiviral responses contributing to increased disease susceptibility and severity compared with acquisition later in life. Using a mouse model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77be64185fdd28ab44bacc75bccf6df5
https://doi.org/10.4049/jimmunol.196.supp.78.7
https://doi.org/10.4049/jimmunol.196.supp.78.7