Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Annie S Park"'
Autor:
Ravikiran M Raju, Mark P Jedrychowski, Jun-Rong Wei, Jessica T Pinkham, Annie S Park, Kathryn O'Brien, German Rehren, Dirk Schnappinger, Steven P Gygi, Eric J Rubin
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003994 (2014)
Unlike most bacterial species, Mycobacterium tuberculosis depends on the Clp proteolysis system for survival even in in vitro conditions. We hypothesized that Clp is required for the physiologic turnover of mycobacterial proteins whose accumulation i
Externí odkaz:
https://doaj.org/article/bdaac5ae17c84c90bb2fac362fa26bd5
Autor:
Ravikiran M. Raju, Tatos Akopian, D. Branch Moody, Johannes Lehmann, Annie S. Park, Eric J. Rubin, Evelyn Zeiler, James C. Sacchettini, Stephan A. Sieber, Tan-Yun Cheng, Anup Aggarwal, Olga Kandror
Publikováno v:
Angewandte Chemie. 130:354-359
Autor:
Evelyn Zeiler, Anup Aggarwal, James C. Sacchettini, Stephan A. Sieber, Eric J. Rubin, Ravikiran M. Raju, Olga Kandror, Tan-Yun Cheng, Tatos Akopian, Johannes Lehmann, D. Branch Moody, Annie S. Park
The spread of antibiotic resistance is a major challenge for treatment of Mycobacterium tuberculosis infection. In addition, efficacy of drugs is often limited by the restricted permeability of the mycomembrane. Frontline antibiotics inhibit mycomemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fe58656ebc7c3b5f3ed07c53b863fb
https://europepmc.org/articles/PMC6104829/
https://europepmc.org/articles/PMC6104829/
Autor:
Thijn R. Brummelkamp, Brent H. Cochran, Irene Wuethrich, Carla P. Guimaraes, Jan E. Carette, Annie S. Park, Maciej Kotecki, Malini Varadarajan, Eric Spooner, Alzbeta Godarova, Hidde L. Ploegh
Publikováno v:
Science. 326:1231-1235
“Haploid Human” Genetic screens can provide direct insight into biological processes that are poorly understood. Carette et al. (p. 1231 ) describe genetic screens using large-scale gene disruption in human cells haploid for all chromosomes excep