Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Annie Molla"'
Autor:
Khalid Ouararhni, Flore Mietton, Jamal S. M. Sabir, Abdulkhaleg Ibrahim, Annie Molla, Raed S. Albheyri, Ali T. Zari, Ahmed Bahieldin, Hervé Menoni, Christian Bronner, Stefan Dimitrov, Ali Hamiche
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The histone variant macroH2A (mH2A), the most deviant variant, is about threefold larger than the conventional histone H2A and consists of a histone H2A-like domain fused to a large Non-Histone Region responsible for recruiting PA
Externí odkaz:
https://doaj.org/article/9e382b68c4fc43db96018983890a6689
Publikováno v:
Biology, Vol 3, Iss 1, Pp 167-175 (2014)
Based on in vitro assays, we performed a High Throughput Screening (HTS) to identify kinase inhibitors among 10,000 small chemical compounds. In this didactic paper, we describe step-by-step the approach to validate the hits as well as the major pitf
Externí odkaz:
https://doaj.org/article/a756cd97bf27499b9547f881e813f210
Publikováno v:
Biology Open, Vol 2, Iss 4, Pp 379-386 (2013)
Summary Histone H3 phosphorylation is the hallmark of mitosis deposited by aurora kinase B. Benzo[e]pyridoindoles are a family of potent, broad, ATP-competitive aurora kinase inhibitors. However, benzo[e]pyridoindole C4 only inhibits histone H3 phosp
Externí odkaz:
https://doaj.org/article/1749ebc7f0754cc6b673f404a81d43eb
Autor:
Mutsuko Minata, Chunyu Gu, Kaushal Joshi, Mariko Nakano-Okuno, Christopher Hong, Chi-Hung Nguyen, Harley I Kornblum, Annie Molla, Ichiro Nakano
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92546 (2014)
Glioblastoma multiforme (GBM) is a highly lethal brain tumor. Due to resistance to current therapies, patient prognosis remains poor and development of novel and effective GBM therapy is crucial. Glioma stem cells (GSCs) have gained attention as a th
Externí odkaz:
https://doaj.org/article/6118982cec9f429e95272c0442851926
Publikováno v:
Oncotarget
Multicellular spheroids are very attractive models in oncology because they mimic the 3D organization of the tumour cells with their microenvironment. We show here using 3 different cell types (mammary TSA/pc, embryonic kidney Hek293 and cervical can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d30fa9eda0bff36b67bbbacf887225
https://doi.org/10.18632/oncotarget.15673
https://doi.org/10.18632/oncotarget.15673
Autor:
Jean-Luc Coll, Annie Molla
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2019, 35 (5), pp.419-422. ⟨10.1051/medsci/2019085⟩
médecine/sciences, EDP Sciences, 2019, 35 (5), pp.419-422. ⟨10.1051/medsci/2019085⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162e0ab9c2190cab1ea4bd517b0aa6b3
https://www.hal.inserm.fr/inserm-02438869
https://www.hal.inserm.fr/inserm-02438869
Autor:
Jean-Luc Coll, Ly-Thuy-Tram Le, Morgane Couvet, Chi-Hung Nguyen, Annie Molla, Bertrand Favier
Publikováno v:
Oncotarget
// Ly-Thuy-Tram Le 1, 2 , Morgane Couvet 1 , Bertrand Favier 3 , Jean-Luc Coll 1 , Chi-Hung Nguyen 4 , Annie Molla 1 1 INSERM UJF U823 Institut Albert Bonniot, Team 5, BP 170, Grenoble Cedex 9, France 2 Department of Biotechnology, University of Scie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c566d3efb486383fd3cf7d663ba628c
https://doi.org/10.18632/oncotarget.4158
https://doi.org/10.18632/oncotarget.4158
Publikováno v:
Current Enzyme Inhibition. 4:153-159
The chromosome passenger complex (CPC) is composed of five proteins: Aurora B kinase, Borealin, INCENP, Survivin and TD-60. CPC functions as an oligo-enzyme, each member activating the catalytic subunit, Aurora B kinase. CPC controls chromosome congr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52d4bc828471bf279d668e1e60ec8907
https://doi.org/10.2174/157340808785909402
https://doi.org/10.2174/157340808785909402
Publikováno v:
médecine/sciences. 24:828-832
Ten year after its discovery Survivin has gained a strategic place within the chromosomal passenger complex. Whereas INCENP, Borealin and Aurora B are fully immobile in the complex, Survivin is mobile on centromere. Its mobility is regulated both by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa0d27f0563b892120949c3ac495bb4
https://doi.org/10.1051/medsci/20082410828
https://doi.org/10.1051/medsci/20082410828
Autor:
Philippe Bouvet, Jacques Côté, Pierre-Yves Perche, Saadi Khochbin, Annie Molla, Stefan Dimitrov, Dimitar Angelov, Fabienne Hans
Publikováno v:
Molecular Cell
Molecular Cell, 2003, 111, pp.1033-1041
Molecular Cell, 2003, 111, pp.1033-1041
The unusual histone variant macroH2A (mH2A) has been associated with repression of transcription, but the molecular mechanisms by which it exerts this function are unknown. Here we have identified a mechanism by which the different domains of mH2A ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ece1ba56cd36546426f0bae932947c
https://doi.org/10.1016/s1097-2765(03)00100-x
https://doi.org/10.1016/s1097-2765(03)00100-x