Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Annie Mirsoian"'
Autor:
Sumedha Roy, Karen Fitzgerald, Almin Lalani, Chin-Wen Lai, Aeryon Kim, Jennie Kim, Peiqi Ou, Annie Mirsoian, Xian Liu, Ambika Ramrakhiani, Huiren Zhao, Hong Zhou, Haoda Xu, Hans Meisen, Chi-Ming Li, Bryan Vander Lugt, Steve Thibault, Christine E. Tinberg, Jason DeVoss, Jackson Egen, Lawren C. Wu, Rajkumar Noubade
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
While the rapid advancement of immunotherapies has revolutionized cancer treatment, only a small fraction of patients derive clinical benefit. Eradication of large, established tumors appears to depend on engaging and activating both innate and adapt
Externí odkaz:
https://doaj.org/article/d95e2a61244d4914a737061907108286
Autor:
Gail D. Sckisel, Annie Mirsoian, Christine M. Minnar, Marka Crittenden, Brendan Curti, Jane Q. Chen, Bruce R. Blazar, Alexander D. Borowsky, Arta M. Monjazeb, William J. Murphy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-11 (2017)
Abstract Background Studies assessing immune parameters typically utilize human PBMCs or murine splenocytes to generate data that is interpreted as representative of immune status. Using splenocytes, we have shown memory CD4-T cells that expand follo
Externí odkaz:
https://doaj.org/article/aa73a2ef07044da8b5b7a4a2e4a5bdc2
Autor:
Anuurad Erdembileg, Annie Mirsoian, Byambaa Enkhmaa, Wei Zhang, Laurel A Beckett, William J Murphy, Lars F Berglund
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121947 (2015)
The overall burden of chronic disease, inflammation and cardiovascular risk increases with age. Whether the relationship between age and inflammation is impacted by presence of an adverse metabolic burden is not known.We determined inflammatory marke
Externí odkaz:
https://doaj.org/article/1c827a5d3a734578a7487924cbb45aaa
Autor:
Arta M Monjazeb, Julia K Tietze, Steven K Grossenbacher, Hui-Hua Hsiao, Anthony E Zamora, Annie Mirsoian, Brent Koehn, Bruce R Blazar, Jonathan M Weiss, Robert H Wiltrout, Gail D Sckisel, William J Murphy
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e102709 (2014)
We have previously demonstrated that immunotherapy combining agonistic anti-CD40 and IL-2 (IT) results in synergistic anti-tumor effects. IT induces expansion of highly cytolytic, antigen-independent "bystander-activated" (CD8(+)CD44high) T cells dis
Externí odkaz:
https://doaj.org/article/8cc561b24e474b77877ada18789ecaf1
Autor:
William J. Murphy, Gail D. Sckisel, Robert J. Canter, Ellen E. Sparger, William T.N. Culp, Julian R. Perks, Abhinav Reddy, Stephen L. Shiao, Amir Kol, Mingyi Chen, Annie Mirsoian, Anthony E. Zamora, Christine Mall, Steven K. Grossenbacher, Michael S. Kent, Arta M. Monjazeb
Supplemental Figure 1: Schema and background data for the canine clinical trial; Supplemental Figure 2: flow cytometry based immunophenotyping of peripheral and tumor draining lymph nodes; Supplemental Figure 3: Flow cytometric assessment of Treg lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50107e36d448f667094eebc473fb59b9
https://doi.org/10.1158/1078-0432.22466829.v1
https://doi.org/10.1158/1078-0432.22466829.v1
Autor:
William J. Murphy, Gail D. Sckisel, Robert J. Canter, Ellen E. Sparger, William T.N. Culp, Julian R. Perks, Abhinav Reddy, Stephen L. Shiao, Amir Kol, Mingyi Chen, Annie Mirsoian, Anthony E. Zamora, Christine Mall, Steven K. Grossenbacher, Michael S. Kent, Arta M. Monjazeb
Table outlining patient characteristics of canine clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec0d68b539805376ec49aed5cedc9b3
https://doi.org/10.1158/1078-0432.22466823.v1
https://doi.org/10.1158/1078-0432.22466823.v1
Autor:
William J. Murphy, Gail D. Sckisel, Robert J. Canter, Ellen E. Sparger, William T.N. Culp, Julian R. Perks, Abhinav Reddy, Stephen L. Shiao, Amir Kol, Mingyi Chen, Annie Mirsoian, Anthony E. Zamora, Christine Mall, Steven K. Grossenbacher, Michael S. Kent, Arta M. Monjazeb
Materials and Methods for flow cytometry, pcr, tissue staining, and metabolomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c15d2cfa96b7845dedd9e726a9a2fb3
https://doi.org/10.1158/1078-0432.22466826
https://doi.org/10.1158/1078-0432.22466826
Autor:
Thomas S. Griffith, Raid Aljumaily, Christine M. Minnar, Robert B. Rebhun, Ziming Wang, Sami Ibrahimi, Alexander A. Merleev, Karen Kelly, Emanual Michael Maverakis, Steven K. Grossenbacher, Dan L. Longo, Ian R. Sturgill, William J. Murphy, Cordelia Dunai, Catherine T. Le, Dennis J. Hartigan-O'Connor, Lam T. Khuat, Sara K. Vesely, Ethan G. Aguilar, Bruce R. Blazar, Robert J. Canter, Kevin Stoffel, Annie Mirsoian, Sarbajit Mukherjee, Jesus I. Luna, Kurt A. Schalper, Alice F. Tarantal, Arta M. Monjazeb, Roslyn Rivkah Isseroff, Gema Méndez-Lagares, Sita S. Withers, Asim Saha, Michael Machiorlatti
Publikováno v:
Nature Medicine. 25:141-151
The recent successes of immunotherapy have shifted the paradigm in cancer treatment, but because only a percentage of patients are responsive to immunotherapy, it is imperative to identify factors impacting outcome. Obesity is reaching pandemic propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34760490f22ca816d2c386561379d71c
https://doi.org/10.1038/s41591-018-0221-5
https://doi.org/10.1038/s41591-018-0221-5
Autor:
Julia K. Tietze, Mingyi Chen, Bruce R. Blazar, Gail D. Sckisel, Myriam N. Bouchlaka, Annie Mirsoian, William J. Murphy
Publikováno v:
Cancer immunology, immunotherapy : CII, vol 64, iss 12
We have demonstrated that immunostimulatory therapies such as interleukin-2 (IL-2) and anti-CD40 (αCD40) can be combined to deliver synergistic anti-tumor effects. While this strategy has shown success, efficacy varies depending on a number of facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1531ad195d600e75df36463bee071d2
https://doi.org/10.1007/s00262-015-1759-4
https://doi.org/10.1007/s00262-015-1759-4
Autor:
Annie Mirsoian, William J. Murphy
Publikováno v:
Immunotherapy. 7:319-322
Within the past decade the usage of cancer immunotherapy has gained momentum, achieving successes within various advancedstaged malignancies and is beginning to be explored as a primary therapeutic rather than secondary to traditional cytoreductive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b230b3ba6f9002acb1528a389d1b75ff
https://doi.org/10.2217/imt.15.12
https://doi.org/10.2217/imt.15.12