Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Annie Mauborgne"'
Autor:
Caroline Isaac, Annie Mauborgne, Alfonso Grimaldi, Kemy Ade, Michel Pohl, Cristina Limatola, Yves Boucher, Caroline Demangel, Laure Guenin-Macé
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 11, p e0006058 (2017)
Mycolactone is a macrolide produced by the skin pathogen Mycobacterium ulcerans, with cytotoxic, analgesic and immunomodulatory properties. The latter were recently shown to result from mycolactone blocking the Sec61-dependent production of pro-infla
Externí odkaz:
https://doaj.org/article/aa52f474023e4c9bbd6c4c41e5e01010
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6874 (2009)
BACKGROUND:The functional significance of proenkephalin systems in processing pain remains an open question and indeed is puzzling. For example, a noxious mechanical stimulus does not alter the release of Met-enkephalin-like material (MELM) from segm
Externí odkaz:
https://doaj.org/article/b99f3199e66143f88adae80ef4e7b367
Autor:
Annie Mauborgne, Guy Simonnet, Meric Ben Boujema, Michel Pohl, John Simmers, Emilie Laboureyras
Publikováno v:
Neuropsychopharmacology
Opioids are a mainstay of pain management but can induce unwanted effects, including analgesic tolerance and paradoxical hyperalgesia, either of which leads to increased pain. Clinically, however, the relationship between these two phenomena remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2547392189f197e4e4845eed3acee3b
https://europepmc.org/articles/PMC8674360/
https://europepmc.org/articles/PMC8674360/
Publikováno v:
Physiology & Behavior. 194:497-504
We explored the molecular and behavioral effects of a perineural Lipopolysaccharide (LPS)-mediated inflammatory priming on the development and maintenance of painful post-traumatic trigeminal neuropathy (PPTTN) following infra-orbital nerve chronic c
Autor:
Yves Boucher, Luis Villanueva, Michel Pohl, Annie Mauborgne, Wisam Dieb, Sylvie Bourgoin, Nathan Moreau
Publikováno v:
Journal of Dental Research. 96:450-457
Whereas neurovascular interactions in spinal neuropathic pain models have been well characterized, little attention has been given to such neurovascular interactions in orofacial neuropathic pain models. This study investigated in male Sprague-Dawley
Autor:
Jean Jacques Benoliel, Michel Pohl, Brigitte Zeau, Cyril Rivat, Chrystel Becker, Aurélie Blugeot, Annie Mauborgne
Publikováno v:
Pain. 150:358-368
Chronic stressful events induce biochemical, physiological and psychological changes, resulting in stress-related neuropsychiatric disorders, such as anxiety or depression. Using repeated social defeat as a stressful event model, we show that this pr
Autor:
Sylvie Bourgoin, Michel Hamon, Michel Pohl, Valérie Kayser, Justine Masson, Alban Latremoliere, Annie Mauborgne
Publikováno v:
The Journal of Neuroscience. 28:8489-8501
Responses resulting from injury to the trigeminal nerve exhibit differences compared with those caused by lesion of other peripheral nerves. With the aim of elucidating the physiopathological mechanisms underlying cephalic versus extracephalic neurop
Autor:
Philippe Sarret, William Rostène, Stéphane Mélik-Parsadaniantz, Patricia Mechighel, Patrick Kitabgi, Romain-Daniel Gosselin, Nicolas Beaudet, Marc-André Dansereau, Michel Pohl, Annie Mauborgne, Blandine Pommier
Publikováno v:
Journal of Neurochemistry. 106:757-769
A better understanding of the mechanisms linked to chemokine pronociceptive effects is essential for the development of new strategies to better prevent and treat chronic pain. Among chemokines, MCP-1/CCL2 involvement in neuropathic pain processing i
Autor:
Babette B. Weksler, Sylvie Bourgoin, Michel Pohl, Annie Mauborgne, Pierre-Olivier Couraud, Nathan Moreau, Luis Villanueva, Yves Boucher, Ignacio A. Romero
Publikováno v:
Pain. 157(4)
Changes in the nerve's microenvironment and local inflammation resulting from peripheral nerve injury participate in nerve sensitization and neuropathic pain development. Taking part in these early changes, disruption of the blood-nerve barrier (BNB)
Autor:
J. Molet, Annie Mauborgne, Michel Pohl, Yves Boucher, David Geny, Luis Villanueva, Vincent Armand, Mickael Diallo
Publikováno v:
Journal of neurochemistry. 136(1)
After peripheral nerve injury microglial reactivity change in the spinal cord is associated with an early activation of Janus kinase (JAK)/STAT3 transduction pathway whose blockade attenuates local inflammation and pain hypersensitivity. However, the