Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Annie M. Welsh"'
Autor:
Jun Yan, Leyan Xu, Annie M Welsh, Glen Hatfield, Thomas Hazel, Karl Johe, Vassilis E Koliatsos
Publikováno v:
PLoS Medicine, Vol 4, Iss 2, p e39 (2007)
Effective treatments for degenerative and traumatic diseases of the nervous system are not currently available. The support or replacement of injured neurons with neural grafts, already an established approach in experimental therapeutics, has been r
Externí odkaz:
https://doaj.org/article/40f9b37e2db04c02b562f0aacef8d648
Autor:
Jun Yan, Leyan Xu, Glen Hatfield, Karl Johe, David Chen, Annie M. Welsh, Thomas G. Hazel, Vassilis E. Koliatsos
Publikováno v:
Transplantation. 82:865-875
Background Experimental therapeutics for degenerative and traumatic diseases of the nervous system have been recently enriched with the addition of neural stem cells (NSCs) as alternatives to fetal tissues for cell replacement. Neurodegenerative dise
Autor:
David Chen, Jun Yan, Leyan Xu, Vassilis E. Koliatsos, Annie M. Welsh, Thomas G. Hazel, Karl Johe
Publikováno v:
STEM CELLS. 24:1976-1985
Amyotrophic lateral sclerosis (ALS) is a target for cell-replacement therapies, including therapies based on human neural stem cells (NSCs). These therapies must be first tested in the appropriate animal models, including transgenic rodents harboring
Publikováno v:
The Journal of Comparative Neurology. 480:101-114
The fate of exogenous neural stem cells (NSCs) in the environment of the adult nervous system continues to be a matter of debate. In the present study, we report that cells of the murine NSC clone C17.2, when grafted into the lumbar segments of the s
Autor:
Glen Hatfield, Jun Yan, Vassilis E. Koliatsos, Karl Johe, Leyan Xu, Annie M. Welsh, Thomas G. Hazel
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 4, Iss 2, p e39 (2007)
PLoS Medicine, Vol 4, Iss 2, p e39 (2007)
Background Effective treatments for degenerative and traumatic diseases of the nervous system are not currently available. The support or replacement of injured neurons with neural grafts, already an established approach in experimental therapeutics,
Publikováno v:
Neuropharmacology. 52(7)
Pyramidal relay neurons in limbic cortex are vulnerable to denervation lesions, i.e. pyramidal neurons in layer IIalpha of piriform cortex undergo transsynaptic apoptosis after lesions that interrupt their inputs from the olfactory bulb. We have prev
Publikováno v:
Journal of neurochemistry. 96(2)
The mechanism of action of commonly used antidepressants remains an issue of debate. In the experiments reported here we studied the effects of three representative compounds, the selective serotonin reuptake inhibitor fluoxetine, the selective serot
Publikováno v:
International Journal of Developmental Neuroscience. 24:592-592
Human embryonic stem cells (HESC) are an unlimited source of cells for stem cell therapies. We investigated the dynamics of integration of HESC-derived neural precursors (NPs) into host neural circuitry. Methods: NP cultures were derived from the NIH