Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Annie M. L. Pettersson"'
Autor:
Karin G. Stenkula, Olga Göransson, Franziska Kopietz, Jurga Laurencikiene, Johanna Säll, Björn Hansson, Mikael Ekelund, Eva Degerman, Wilhelm Linder, Annie M. L. Pettersson, Florentina Negoita
Publikováno v:
Cellular Signalling. 55:73-80
Aims/hypothesis Salt-inducible kinase 2 (SIK2) is downregulated in adipose tissue from obese or insulin-resistant individuals and inhibition of SIK isoforms results in reduced glucose uptake and insulin signalling in adipocytes. However, the regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbec547807d95c8482db097e00cb9f0
https://doi.org/10.1016/j.cellsig.2018.12.011
https://doi.org/10.1016/j.cellsig.2018.12.011
Autor:
Annie M. L. Pettersson, Agné Kulyté, Jurga Laurencikiene, Yasmina Belarbi, Peter Arner, Ingrid Dahlman
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 312:E482-E494
The key pathological link between obesity and type 2 diabetes is insulin resistance, but the molecular mechanisms are not entirely identified. micro-RNAs (miRNA) are dysregulated in obesity and may contribute to insulin resistance. Our objective was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8715ed4446aaf4ae223f21b36f586e3a
https://doi.org/10.1152/ajpendo.00251.2016
https://doi.org/10.1152/ajpendo.00251.2016
Autor:
Annie M. L. Pettersson, Alexander V. Chibalin, Ingrid Dahlman, Peter Arner, Britta M Stenson, Niklas Mejhert, Gaby Åström, Daniel P. Andersson, Jurga Laurencikiene, J. Krätzel, Silvia Lorente-Cebrián
Publikováno v:
Diabetologia. 56:2044-2054
Obesity increases the risk of developing type 2 diabetes mellitus, characterised by impaired insulin-mediated glucose uptake in peripheral tissues. Liver X receptor (LXR) is a positive regulator of adipocyte glucose transport in murine models and a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b953008f7b5f042e9b900c696eee95c
https://doi.org/10.1007/s00125-013-2954-5
https://doi.org/10.1007/s00125-013-2954-5
Autor:
Britta M Stenson, Gaby Åström, Lennart Blomqvist, Mikael Rydén, Johan W. E. Jocken, Ingrid Dahlman, Peter Arner, Nicolas Venteclef, Victoria Wang, Dominique Langin, Karine Clément, Annie M. L. Pettersson, Aline Mairal, Jurga Laurencikiene
Publikováno v:
Journal of Biological Chemistry; Vol 286
The Liver X receptor (LXR) is an important regulator of carbohydrate and lipid metabolism in humans and mice. We have recently shown that activation of LXR regulates cellular fuel utilization in adipocytes. In contrast, the role of LXR in human adipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586b734d99026a699ad9d07c25a04cbc
Autor:
Christel Björk, Annie M. L. Pettersson, Juan R. Acosta, Johan Krätzel, Britta M Stenson, Lennart Blomqvist, Dominique Langin, Jurga Laurencikiene, Peter Arner, Nathalie Viguerie
Publikováno v:
Diabetologia. 58(9)
Dysregulated expression of metabolic and inflammatory genes is a prominent consequence of obesity causing insulin resistance and type 2 diabetes. Finding causative factors is essential to understanding progression of these pathologies and discovering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded59a762f0bf6f6d4ac6ddc986ecff7
https://pubmed.ncbi.nlm.nih.gov/26115698
https://pubmed.ncbi.nlm.nih.gov/26115698
Autor:
Mikael Ekelund, Johanna Säll, Yuedan Zhou, Daniel P. Andersson, Eva Degerman, Olga Göransson, Karin G. Stenkula, Ola Hansson, Wilhelm Linder, Sebastian Wasserstrom, Annie M. L. Pettersson, Jurga Laurencikiene, Emma Henriksson, Christel Björk
Publikováno v:
Diabetologia
Aims/hypothesis Salt-inducible kinases (SIKs) are related to the metabolic regulator AMP-activated protein kinase (AMPK). SIK2 is abundant in adipose tissue. The aims of this study were to investigate the expression of SIKs in relation to human obesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623d7b254d60f759212c9cbd69d1ca7d