Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Annie J Zalon"'
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204438 (2018)
Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disorder caused by a polyglutamine-encoding CAG repeat expansion in the ATXN3 gene which encodes the deubiquitinating enzyme, ATXN3. Several mechanisms have been propose
Externí odkaz:
https://doaj.org/article/dbb46c065ea745759fab0c7153328a07
Publikováno v:
The Journal of Neuroscience. 43:2615-2629
Macroautophagy is a catabolic process that coordinates with lysosomes to degrade aggregation-prone proteins and damaged organelles. Loss of macroautophagy preferentially affects neuron viability and is associated with age-related neurodegeneration. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811dcafe21b78d79c3ad695165c80ce0
https://doi.org/10.1523/jneurosci.0610-22.2023
https://doi.org/10.1523/jneurosci.0610-22.2023
Autor:
Hayley S. McLoughlin, Katherine Gundry, Orion Rainwater, Kristen H. Schuster, Isabel G. Wellik, Annie J. Zalon, Michael A. Benneyworth, Lynn E. Eberly, Gülin Öz
Publikováno v:
Annals of Neurology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1063716b1d3b4df40777f90d6cc3b14
https://doi.org/10.1002/ana.26713
https://doi.org/10.1002/ana.26713
Autor:
Kristen H. Schuster, Annie J. Zalon, Hongjiu Zhang, Danielle M. DiFranco, Nicholas R. Stec, Zaid Haque, Kate G. Blumenstein, Amanda M. Pierce, Yuanfang Guan, Henry L. Paulson, Hayley S. McLoughlin
Publikováno v:
J Neurosci
Spinocerebellar ataxia Type 3 (SCA3), the most common dominantly inherited ataxia, is a polyglutamine neurodegenerative disease for which there is no disease-modifying therapy. The polyglutamine-encoding CAG repeat expansion in theATXN3gene results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292876747fad3ec07c37933f99219098
https://doi.org/10.1523/jneurosci.1954-20.2021
https://doi.org/10.1523/jneurosci.1954-20.2021
Autor:
Kristen H. Schuster, Annie J. Zalon, Danielle M. DiFranco, Alexandra F. Putka, Nicholas Stec, Sabrina Jarrah, Arsal Naeem, Zaid Haque, Hongjiu Zhang, Yuanfang Guan, Hayley S. McLoughlin
Spinocerebellar ataxia type 3 (SCA3) is the most common dominantly inherited ataxia. Currently, no preventative or disease-modifying treatments exist for this progressive neurodegenerative disorder, although efforts using gene silencing approaches ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c572e0f051424895909d2b7bfe4c0af
https://doi.org/10.1101/2022.07.18.500473
https://doi.org/10.1101/2022.07.18.500473
Autor:
Logan M. Morrison, Hongjiu Zhang, Annie J. Zalon, Vikram G. Shakkottai, Yuanfang Guan, David D. Bushart, Hayley S. McLoughlin, Henry L. Paulson
Publikováno v:
Cerebellum
Spinocerebellar ataxia type 3 (SCA3) is the second-most common CAG repeat disease, caused by a glutamine-encoding expansion in the ATXN3 protein. SCA3 is characterized by spinocerebellar degeneration leading to progressive motor incoordination and ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf7d0b2b7ca78bbdde521097742f38b
https://pubmed.ncbi.nlm.nih.gov/32789747
https://pubmed.ncbi.nlm.nih.gov/32789747
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204438 (2018)
PLoS ONE
PLoS ONE
Spinocerebellar ataxia type 3 (SCA3) is a dominantly inherited neurodegenerative disorder caused by a polyglutamine-encoding CAG repeat expansion in the ATXN3 gene which encodes the deubiquitinating enzyme, ATXN3. Several mechanisms have been propose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e231d58c4b99a169ed59f0b422676a
http://europepmc.org/articles/PMC6145529?pdf=render
http://europepmc.org/articles/PMC6145529?pdf=render