Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Annie Grouiller"'
Publikováno v:
ChemPhysChem. 4:608-611
Publikováno v:
Journal of Carbohydrate Chemistry. 14:1387-1391
Analogues of nucleosides in which the nucleobase is fixed onto the C-4 of the sugar moiety are generally prepared either from 4,5-unsaturated sugar derivatives or via a formaldehyde condensation.1 We tested the furanosyl bromide reactivity of 1 2 tow
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 14:511-515
Bicyclonucleosides like 3 are active against HIV-1 and HIV-2 after phosphorylation. They most probably act as their native bicyclic form fundamentally different, structurally, from that of AZT.
Publikováno v:
Tetrahedron. 50:6689-6694
A conformational analysis of 1-(1-Deoxy-β-D-Psicorofuranosyl) thymine (1) and 1-(β-D-Ribofuranosyl) thymine (2) has been performed by using the semiempirical AM1 methodology. A topological analysis of the total charge density and the Laplacian of b
Autor:
Gérard Descotes, Bernard Fenet, Annie Grouiller, Guo-Rong Chen, Jérémie Le Quan Tuoi, Valérie Uteza
Publikováno v:
Tetrahedron. 49:8579-8588
The 1′-cyano-2′,3′-D-unsaturated nucleoside 8 was synthesised according to the following steps. Photobromination of the ribofuranosyl cyanide 1 using N-bromosuccinimide (NBS) as a radical source gave the two isomers of the new C-1 gem disubstit
Autor:
Hyppolite Ntede Nga, Isabelle Eynard, Gérard Descotes, Annie Grouiller, Véronique Faivre-Buet
Publikováno v:
Journal of Carbohydrate Chemistry. 12:349-356
D-Psico- and D-sorbo-furanosyl derivatives 3 and 6 were synthesized in two steps through the methylenation of the D-ribono- and D-xylono-lactones 1 and 4 with dicyclopentadienyldimethyltitanium, followed by the cis-dihydroxylation of the resultant ol
Publikováno v:
ChemInform. 27
Analogues of nucleosides in which the nucleobase is fixed onto the C-4 of the sugar moiety are generally prepared either from 4,5-unsaturated sugar derivatives or via a formaldehyde condensation.1 We tested the furanosyl bromide reactivity of 1 2 tow
Publikováno v:
Nucleosides and Nucleotides. 11:1651-1660
The use of D-(+)-ribonic γ-lactone 1a,b as a chiral synthon leads to an efficient synthesis of the ketose 1-deoxy-D-psicofuranose 2a,b. Condensation of the corresponding acetyl derivative 3a,b with silylated thymine, followed by deprotection of 4a,b
Publikováno v:
Nucleosides and Nucleotides. 11:1411-1424
Various routes to the targets 1, 2, 3, 1-deoxy-psicofuranosyl nucleoside analogues related to anti-HIV agents, are reported. Two routes afforded their 6′-benzylated derivatives 9, 10 and 15. Only the epoxide 12 and deoxynucleosides 19 and 22 were a
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry. 4(6)