APPINetwork: an R package for building and computational analysis of protein–protein interaction networks

Autor: Simon Gosset, Annie Glatigny, Mélina Gallopin, Zhou Yi, Marion Salé, Marie-Hélène Mucchielli-Giorgi

Publikováno v: PeerJ, Vol 10, p e14204 (2022)

Background Protein–protein interactions (PPIs) are essential to almost every process in a cell. Analysis of PPI networks gives insights into the functional relationships among proteins and may reveal important hub proteins and sub-networks correspo

Externí odkaz: https://doaj.org/article/5ab6c13515254043b10e23f757262ab1

Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies

Autor: Laras Pitayu, Vincent Procaccio, Agnès Rötig, Jean-Paul Lasserre, Pascal Reynier, Annie Glatigny, Déborah Tribouillard-Tanvier, Natalia Skoczen, Joanna Rytka, Alain Dautant, Roza Kucharczyk, Lars M. Steinmetz, Jean-Paul di Rago, Raeka S. Aiyar, Marc Blondel, Geneviève Dujardin, Agnès Delahodde

Publikováno v: Disease Models & Mechanisms, Vol 8, Iss 6, Pp 509-526 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2015, 8 (6), pp.509-26. ⟨10.1242/dmm.020438⟩
Disease Models & Mechanisms, Cambridge Company of Biologists, 2015, 8 (6), pp.509-26
Disease Models & Mechanisms, 2015, 8 (6), pp.509-26. ⟨10.1242/dmm.020438⟩
Disease Models & Mechanisms, 2015, 8 (6), pp.509-26

Mitochondrial diseases are severe and largely untreatable. Owing to the many essential processes carried out by mitochondria and the complex cellular systems that support these processes, these diseases are diverse, pleiotropic, and challenging to st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8dd9438fa3765bca95532112ed94dd
http://dmm.biologists.org/content/8/6/509

SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1

Autor: Marie-Hélène Mucchielli-Giorgi, Renaud Legouis, Zhou Yi, Virginie Redeker, Marion Manil-Ségalen, Laila Sago, Annie Glatigny

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2016, 15 (5), pp.1515-1523. ⟨10.1021/acs.jproteome.5b01158⟩
Journal of Proteome Research, 2016, 15 (5), pp.1515-1523. ⟨10.1021/acs.jproteome.5b01158⟩
Journal of Proteome Research, American Chemical Society, 2016, 15 (5), pp.1515-1523. 〈10.1021/acs.jproteome.5b01158〉

International audience; Affinity purifications followed by mass spectrometric analysis are used to identify protein-protein interactions. Because quantitative proteomic data are noisy, it is necessary to develop statistical methods to eliminate false

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee1a827972e742ae781d7b117c721b1
https://hal.archives-ouvertes.fr/hal-01405694

Human GABARAP can restore autophagosome biogenesis in a C. elegans lgg-1 mutant

Autor: Annie Glatigny, Céline Jenzer, Céline Largeau, Christophe Lefebvre, Marion Manil-Ségalen, Renaud Legouis

Publikováno v: Autophagy. 10(10)

We recently described in C. elegans embryos, the acquisition of specialized functions for orthologs of yeast Atg8 (e.g., mammalian MAP1LC3/LC3) in allophagy, a selective and developmentally regulated autophagic process. During the formation of double

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69593cc8c9ed2a610300cd270405167e
https://pubmed.ncbi.nlm.nih.gov/25126728

The hxB gene, necessary for the post-translational activation of purine hydroxylases in Aspergillus nidulans, is independently controlled by the purine utilization and the nicotinate utilization transcriptional activating systems

Autor: Claudio Scazzocchio, Cecchetto G, Laila Amrani, Annie Glatigny

Publikováno v: Molecular Microbiology. 31:1065-1073

Molybdenum-containing enzymes of the hydroxylase class (such as xanthine dehydrogenase, aldehyde oxidase and nicotinate dehydrogenase) require a terminal sulphur atom attached to the molybdenum to hydroxylate their specific substrates. The transulphu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6092b65fec23db0e451e55c4706b3b2f
https://doi.org/10.1046/j.1365-2958.1999.01242.x