Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Annie Genton"'
Publikováno v:
Europe PubMed Central
The major tyrosine protein kinase, HPK40, isolated from HL-60, the preparation of which is described elsewhere (Ernould, A.P., Ferry, G., Barret, J.M., Genton, A. and Boutin, J.A., Eur. J. Biochem., 214, 503-514), was investigated as to its specifici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f1fd622d82d7a6e64a06878f7736ed
https://doi.org/10.1111/j.1399-3011.1994.tb00549.x
https://doi.org/10.1111/j.1399-3011.1994.tb00549.x
Autor:
Gordon C. Tucker, Marc Bertrand, Armelle Loynel, Jean-Luc Fauchère, Jean-Michel Henlin, Annie Genton, C. Desmet-Beaufort, Jean A. Boutin, Ghanem Atassi, Nathalie Kucharczyk
Publikováno v:
The Journal of Peptide Research. 57:85-96
A complete 331 776-member library of tetrapeptides made of 24 amino acid building blocks was synthesized robotically on solid phase and subjected to a deconvolution based on the inhibitory potency of the sublibraries in a HPLC assay of the S-farnesyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2395da9f5193c226f2fa46503384a7
https://doi.org/10.1034/j.1399-3011.2001.00787.x
https://doi.org/10.1034/j.1399-3011.2001.00787.x
Autor:
Gilles Ferry, Gordon C. Tucker, Annie Genton, Ghanem Atassi, Jean-Luc Fauchère, Christine Desmet, Jean A. Boutin, Philippe Hennig
Publikováno v:
European Journal of Pharmacology. 351:225-233
Matrix metalloproteinases are zinc metalloenzymes involved in remodelling of the extracellular matrix. We compared the anti-invasive properties of a zinc ejector matrix metalloproteinase inhibitor with those of reference compounds (hydroxamic acid-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29097c7d35057636d452305c4bbf285
https://doi.org/10.1016/s0014-2999(98)00304-5
https://doi.org/10.1016/s0014-2999(98)00304-5
Autor:
Valérie Pérez, Monique Anstett, Jean-Pierre Bizzari, Stéphane Léonce, Alain Pierré, Annie Genton, Ghanem Atassi
Publikováno v:
Biochemical Pharmacology. 44:1707-1715
A new triazinoaminopiperidine derivative, Servier 9788 (S9788), was investigated for its ability to increase Adriamycin (ADR) accumulation and retention in two rodent (P388/ADR and DC-3F/AD) and three human (KB-A1, K562/R and COLO 320DM) cell lines d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbb5bd6df988e8052bff9982d9e2aea
https://doi.org/10.1016/0006-2952(92)90063-o
https://doi.org/10.1016/0006-2952(92)90063-o
Autor:
Patrick Casara, Annie Genton, Marc Bertrand, Françoise Perron-Sierra, Dominique Saint Dizier, Gordon C. Tucker
Publikováno v:
ChemInform. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8565d695f9dcb97df947e9e8e859f0c
https://doi.org/10.1002/chin.200309080
https://doi.org/10.1002/chin.200309080
Autor:
Marc Bertrand, Dominique Saint Dizier, Annie Genton, Patrick Casara, Gordon C. Tucker, Françoise Perron-Sierra
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(22)
A novel series of potent and specific alpha(v) integrin antagonists has been obtained by aminoalkyl substitutions on benzocyloheptene acetic acids as a rigid GD bioisostere. The preferred compounds 1-2, 1-3 and 1-8, showed nano- to subnanomolar IC(50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f21b4ac0a6e6dbdfafff6a13cbd4d2
https://pubmed.ncbi.nlm.nih.gov/12392735
https://pubmed.ncbi.nlm.nih.gov/12392735
Publikováno v:
Biochemical pharmacology. 46(3)
Tyrosine protein kinases (TPKs) play a major role in the transformation of cells. They are currently used as molecular targets for new generations of anticancer compounds. Numerous TPKs have been described from various tissues using either classical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eafa95b936aa0a2242340f9f69ad039
https://pubmed.ncbi.nlm.nih.gov/8347167
https://pubmed.ncbi.nlm.nih.gov/8347167
Publikováno v:
European journal of biochemistry. 214(2)
The major tyrosine protein kinase from HL60 (a human non-differentiated promyelocytic cell line) has been purified almost to homogeneity as judged by silver-stained SDS/PAGE. The procedure involved four chromatographic steps: DEAE-Sepharose, casein-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066dbefd864b7fb0571f8a9ec35eb6e4
https://pubmed.ncbi.nlm.nih.gov/8513800
https://pubmed.ncbi.nlm.nih.gov/8513800
Autor:
Marie-Hélène Rouillon, Gilles Ferry, Anne-Pascale Ernould, Annie Genton, Jean-Marc Barret, Jean A. Boutin
Publikováno v:
Chemico-biological interactions. 86(1)
Tyrosine as well as serine/threonine protein kinase inhibitors have potentially two sites of interaction with their targets: the protein-substrate binding site and the ATP binding site. The latter could be modelized by measuring the capacity of prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8159a93c7c533ad453bbdd2bdea5e8
https://pubmed.ncbi.nlm.nih.gov/8431962
https://pubmed.ncbi.nlm.nih.gov/8431962
Publikováno v:
Europe PubMed Central
A new HPLC method has been developed to assay tyrosine protein kinase activity. Using hydrophilic interaction chromatography, it is possible to resolve the four components of the incubation medium: substrate peptide, [ 32 P]phosphorylated peptide, un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0779fb23a316e841e46876fa4fddd0
https://pubmed.ncbi.nlm.nih.gov/1478977
https://pubmed.ncbi.nlm.nih.gov/1478977