Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Annie Gahm"'
Publikováno v:
Scopus-Elsevier
ResearcherID
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The activation of the caspase family of proteases has been detected in numerous cell systems and appears to function as a common pathway through which apoptotic mechanisms may operate. Caspases are synthesized as precursors (pro-caspases) and are con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2895ea0d0293ee72da15fa7e739ffc38
https://doi.org/10.1038/sj.cdd.4400536
https://doi.org/10.1038/sj.cdd.4400536
Publikováno v:
FEBS Letters. 351:150-154
Isolated rat liver nuclei were incubated in the presence of divalent cations, and the mechanisms underlying the subsequent chromatin fragmentation were investigated. Either of the two cations, Ca2+ or Mg2+ was sufficient to produce chromatin fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f331cfa8b0e614c931cafbb6816f60ad
https://doi.org/10.1016/0014-5793(94)00827-2
https://doi.org/10.1016/0014-5793(94)00827-2
Autor:
Annie Gahm, Juan Llopis, Dominic-Luc Webb, Per Olof Berggren, Sek C. Chow, George E.N. Kass, Sten Orrenius
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1223:226-233
The plasma membrane Ca2+ carrier system involved in receptor-mediated Ca2+ entry was studied. Using the Ca2+ readdition protocol, the rate of cytosolic free Ca2+ concentration ([Ca2+]i) increase in vasopressin-pretreated hepatocytes was significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a966766f22c3b72af23c4692e98bb488
https://doi.org/10.1016/0167-4889(94)90230-5
https://doi.org/10.1016/0167-4889(94)90230-5
Publikováno v:
Cellular Signalling. 6:493-501
The regulation of Ca 2+ influx in rat hepatocytes by glucagon and cyclic AMP (cAMP) was investigated. Exposing hepatocytes to glucagon resulted in an increase in the initial rate of Ca 2+ entry. The concentrations of glucagon producing half-maximal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d1a6d150c6ea430f0479afed2b7c53
https://doi.org/10.1016/0898-6568(94)90003-5
https://doi.org/10.1016/0898-6568(94)90003-5
Autor:
Steven K. Duddy, George E.N. Kass, Annie Gahm, Juan Llopis, Sten Orrenius, Geoffrey C. Farrell
Publikováno v:
Biochemical Pharmacology. 45:2209-2214
In the isolated perfused rat liver 2,5-di(tert-butyl)hydroquinone (tBuHQ), a selective inhibitor of the endoplasmic reticulum Ca2+ pump, induces a prolonged glucose output and stimulates Ca2+ efflux. The present study shows that tBuHQ depleted the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a482d025e1157e696d5807328d3c77a
https://doi.org/10.1016/0006-2952(93)90191-x
https://doi.org/10.1016/0006-2952(93)90191-x
Publikováno v:
Biochemical Journal. 284:243-247
Receptor-mediated Ca2+ entry was studied in fura-2-loaded isolated hepatocytes. Emptying of internal Ca2+ stores by treatment with either the Ca(2+)-mobilizing hormone vasopressin or the inhibitors of the microsomal Ca2+ pump, 2,5-di-(t-butyl)-1,4-be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eb881a08cd46210c92aad2493b78ef
https://doi.org/10.1042/bj2840243
https://doi.org/10.1042/bj2840243
Autor:
Annie Gahm, Atsushi Nakazawa, Camilla Köhler, Sten Orrenius, Takafumi Noma, Boris Zhivotovsky
Publikováno v:
FEBS Letters. 447:10-12
The release of two mitochondrial proteins, cytochrome c and apoptosis-inducing factor (AIF), into the soluble cytoplasm of cells undergoing apoptosis is well established. Using spectrophotometric determination of enzyme activity, the accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eccac15ab51fa4d35ae58015fdaef2
https://doi.org/10.1016/s0014-5793(99)00251-3
https://doi.org/10.1016/s0014-5793(99)00251-3
Publikováno v:
Biochemical and biophysical research communications. 233(1)
To investigate the involvement of different proteases in the execution step of apoptosis and to determine their intracellular location, isolated rat thymocyte nuclei were incubated either in the presence of Ca2+ and Mg2+ or with cytosolic extract fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5b629b99bc7fffbc0bfc5fcdd14480
https://pubmed.ncbi.nlm.nih.gov/9144403
https://pubmed.ncbi.nlm.nih.gov/9144403
Publikováno v:
Experimental cell research. 221(2)
To investigate the involvement of proteases in apoptosis, rat thymocytes were treated with the glucocorticoid hormone methylprednisolone or the topoisomerase II inhibitor etoposide in the presence of selective substrate inhibitors of either interleuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61225798b04614efcbc866869c9b8496
https://pubmed.ncbi.nlm.nih.gov/7493640
https://pubmed.ncbi.nlm.nih.gov/7493640
The effects of two inhibitors of the microsomal Ca(2+)-ATPase, thapsigargin and 2,5-di-(t-butyl)-1,4-benzohydroquinone, were compared in hepatocytes and in a T-cell line (JURKAT). Both compounds mobilized the same intracellular Ca2+ pool, which conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8883e2ba62ee47d529a68ffb5d7aae
https://europepmc.org/articles/PMC1151269/
https://europepmc.org/articles/PMC1151269/
