Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Annie Etuk"'
Autor:
Christos Georgiadis, Lauren Nickolay, Farhatullah Syed, Hong Zhan, Soragia Athina Gkazi, Annie Etuk, Ulrike Abramowski-Mock, Roland Preece, Piotr Cuber, Stuart Adams, Giorgio Ottaviano, Waseem Qasim
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Umbilical cord blood (UCB) T cells exhibit distinct naive ontogenetic profiles and may be an attractive source of starting cells for the production of chimeric antigen receptor (CAR) T cells. Pre-selection of UCB-T cells on the basis of CD62L express
Externí odkaz:
https://doaj.org/article/cdb82ae8baf04b8389ea2a1288375c7b
Autor:
Giorgio, Ottaviano, Christos, Georgiadis, Soragia Athina, Gkazi, Farhatullah, Syed, Hong, Zhan, Annie, Etuk, Roland, Preece, Jan, Chu, Agnieszka, Kubat, Stuart, Adams, Paul, Veys, Ajay, Vora, Kanchan, Rao, Waseem, Qasim, Daesik, Kim
Publikováno v:
Science translational medicine. 14(668)
Genome editing of allogeneic T cells can provide “off-the-shelf” alternatives to autologous chimeric antigen receptor (CAR) T cell therapies. Disruption of T cell receptor α chain (TRAC) to prevent graft-versus-host disease (GVHD) and removal of
Autor:
Arnold Kloos, Christos Georgiadis, Annie Etuk, Soragia Athina Gkazi, Farhatullah Syed, Toni Braybrook, Hong Zhan, Renuka Kadirkamanathan, Nadine Kattre, Kerstin Görlich, Thomas Fangmann, Axel Schambach, Martin G. Sauer, Michael Heuser, Waseem Qasim
Publikováno v:
Blood. 140:7425-7426
Autor:
Robert Chiesa, Christos Georgiadis, Giorgio Ottaviano, Farhatullah Syed, Toni Braybrook, Annie Etuk, Hong Zhan, Soragia Athina Gkazi, Roland Preece, Stuart Adams, Rebecca Thomas, Arnold Awuah, Kimberly Gilmour, Lana Mhaldien, Jan Chu, Danielle Pinner, Agnieszka Kubat, Paul Veys, Kanchan Rao, Giovanna Lucchini, David O'Connor, Ajay Vora, Waseem Qasim
Publikováno v:
Blood. 140:4579-4580
Autor:
Danielle Pinner, Farhatullah Syed, Christos Georgiadis, Paul Veys, Sarah Inglott, Agnieszka Kubat, Annie Etuk, Ajay Vora, Giorgio Ottaviano, Stuart Adams, Susanne Kricke, Kanchan Rao, Waseem Qasim, Soragia Athina Gkazi, Dariusz Ladon, Kimberly Gilmour, Natalia Izotova, Hong Zhan, Jan Chu
Publikováno v:
Blood. 138:4838-4838
Background 'Off-the-shelf' CAR T cell therapies are being investigated as alternatives to autologous CAR therapy, and can be generated using genome editing from allogeneic donors. Strategies to address HLA barriers include disruption of T cell recept
Autor:
Christos Georgiadis, Waseem Qasim, Abraham Christi, Soragia Athina Gkazi, Roland Preece, Annie Etuk, Jane Rasaiyaah
Publikováno v:
Blood. 134:3219-3219
Chimeric antigen receptor (CAR) T cell approaches to target T cell malignancies have been hampered by the fundamental issue of 'T v T' fratricide when T lineage antigens such as CD3 or CD7 are targeted. Genome-editing can be employed to efficiently e