Výsledky vyhledávání - "Annie Desmons"

Akademický článek

The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth

Autor: Mélanie Rose, Marie Duhamel, Soulaimane Aboulouard, Firas Kobeissy, Emilie Le Rhun, Annie Desmons, Dominique Tierny, Isabelle Fournier, Franck Rodet, Michel Salzet

Publikováno v: Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 31-46 (2020)

Tumors are characterized by the presence of malignant and non-malignant cells, such as immune cells including macrophages, which are preponderant. Macrophages impact the efficacy of chemotherapy and may lead to drug resistance. In this context and ba

Externí odkaz: https://doaj.org/article/9bd39da1750f4d0bb97914d5fa1e172f

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Akademický článek

Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech.

Autor: Céline Meriaux, Karim Arafah, Aurélie Tasiemski, Maxence Wisztorski, Jocelyne Bruand, Céline Boidin-Wichlacz, Annie Desmons, Delphine Debois, Olivier Laprévote, Alain Brunelle, Terry Gaasterland, Eduardo Macagno, Isabelle Fournier, Michel Salzet

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18359 (2011)

The adult medicinal leech central nervous system (CNS) is capable of regenerating specific synaptic circuitry after a mechanical lesion, displaying evidence of anatomical repair within a few days and functional recovery within a few weeks. In the pre

Externí odkaz: https://doaj.org/article/9d683829d9fd4b9a99ecb39d7517644f

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Lipidomics for Clinical Diagnosis: Dye-Assisted Laser Desorption/Ionization (DALDI) Method for Lipids Detection in MALDI Mass Spectrometry Imaging

Autor: Olivier Kerdraon, Isabelle Fournier, Rémi Longuespée, Karim Arafah, Michel Salzet, Annie Desmons

Publikováno v: OMICS: A Journal of Integrative Biology. 18:487-498

Lipid-based biomarkers for research and diagnosis are rapidly emerging to unpack the basis of person-to-person and population variations in disease susceptibility, drug and nutritional responses, to name but a few. Hence, with the advent of MALDI Mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb69ec3e5fb0ffb6113faf7d9933f2ed
https://doi.org/10.1089/omi.2013.0175

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HFIP Extraction Followed by 2D CTAB/SDS-PAGE Separation: A New Methodology for Protein Identification from Tissue Sections after MALDI Mass Spectrometry Profiling for Personalized Medicine Research

Autor: Michel Salzet, Robert Day, Rémi Longuespée, Annie Desmons, Olivier Kerdraon, Isabelle Fournier, Christophe Tastet

Publikováno v: OMICS: A Journal of Integrative Biology. 18:374-384

Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) and profiling technology have become the easiest methods for quickly accessing the protein composition of a tissue area. Unfortunately, the demand for the identificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3260e123c149d506cb246df57671ac94
https://doi.org/10.1089/omi.2013.0176

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Proteomic analyses of serous and endometrioid epithelial ovarian cancers - Cases studies - Molecular insights of a possible histological etiology of serous ovarian cancer

Autor: Denis Vinatier, Maxence Wisztorski, Olivier Kerdraon, Isabelle Fournier, Adesuwa Ighodaro, Hugo Gagnon, Robert Day, Rémi Longuespée, Jocelyn Dupuis, Michel Salzet, Charlotte Boyon, Kurstin Strupat, Annie Desmons, Claire Dauly

Publikováno v: PROTEOMICS - Clinical Applications. 7:337-354

Epithelial ovarian carcinogenesis may occur de novo on the surface of ovarian mesothelial epithelial cells or from cells originating in other organs. Foreign Müllerian cell intrusion into the ovarian environment has been hypothesized to explain the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda762f1d22a011483cd04cd42710b8d
https://doi.org/10.1002/prca.201200079

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Spatially-resolved protein surface microsampling from tissue sections using liquid extraction surface analysis

Autor: Michel Salzet, Benoit Fatou, Annie Desmons, Maxence Wisztorski, Isabelle Fournier, Jean-Pascal Gimeno, Julien Franck, Jusal Quanico

Publikováno v: Proteomics
Proteomics, Wiley-VCH Verlag, 2016, 16 (11-12), pp.1622-1632. ⟨10.1002/pmic.201500508⟩
Proteomics, 2016, 16 (11-12), pp.1622-1632. ⟨10.1002/pmic.201500508⟩

International audience; Tissue microenvironment characterization presents a challenge for a better understanding of the full complexity of a pathology. Unfortunately, making a precise "picture" of the disease needs an efficient microsampling method c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37545af07d527187942e43265223af7e
https://www.hal.inserm.fr/inserm-02940393/document

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Ovarian cancer molecular pathology

Autor: Eric Leblanc, Robert Day, Isabelle Farre, Rémi Longuespée, Maxence Wisztorski, Isabelle Fournier, François D'Anjou, Denis Vinatier, Charlotte Boyon, Michel Salzet, Annie Desmons, Kévin Ly

Publikováno v: Cancer and Metastasis Reviews. 31:713-732

Ovarian cancer (OVC) is the fourth leading cause of cancer mortality among women in Europe and the United States. Its early detection is difficult due to the lack of specificity of clinical symptoms. Unfortunately, late diagnosis is a major contribut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020223e23bf3b36352ca955e5bb13e6e
https://doi.org/10.1007/s10555-012-9383-7

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The C-terminal fragment of the immunoproteasome PA28S (Reg alpha) as an early diagnosis and tumor-relapse biomarker: evidence from mass spectrometry profiling

Autor: Denis Vinatier, Robert Day, Rémi Longuespée, Annie Desmons, Olivier Kerdraon, Isabelle Fournier, Charlotte Boyon, Michel Salzet, Amélie Jacquet, Céline Castellier

Publikováno v: Histochemistry and Cell Biology. 138:141-154

This study reports on the C-terminal fragment of the 11S proteasome activator complex (PA28 or Reg alpha), a novel ovarian-specific biomarker of early and late stages of ovarian cancer (OVC) relapse, in patient biopsies after chemotherapy. A total of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977ee2fe1c63e43f05a48ba734c8d952
https://doi.org/10.1007/s00418-012-0953-0

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Spectroimmunohistochemistry: a novel form of MALDI mass spectrometry imaging coupled to immunohistochemistry for tracking antibodies

Autor: Rémi Longuespée, Isabelle Farre, Eric Leblanc, Charlotte Boyon, Robert Day, Annie Desmons, Olivier Kerdraon, Isabelle Fournier, Michel Salzet, Denis Vinatier

Publikováno v: Omics : a journal of integrative biology. 18(2)

MALDI mass spectrometry imaging (MALDI-MSI) is currently used for clinical applications, such as biomarker identification, particularly for the study of solid tumors. The ability to map specific compounds that have been determined to be biomarkers an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b9a8fbdae822e1320fa1f1c08b918
https://pubmed.ncbi.nlm.nih.gov/24351082

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Involvement of nitric oxide through endocannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech

Autor: Dominique Croix, Isabelle Fournier, Karim Arafah, Annie Desmons, Jacopo Vizioli, Michel Salzet

Publikováno v: Glia. 61(4)

The medicinal leech is notable for its capacity to regenerate its central nervous system (CNS) following mechanical trauma. Using an electrochemical nitric oxide (NO)-selective electrode to measure NO levels, we found that the time course of NO relea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5f73560de5a12b51ec9d227f4afa63
https://pubmed.ncbi.nlm.nih.gov/23355252

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