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pro vyhledávání: '"Annie D'AmoursA. D'Amours"'
Publikováno v:
Biochemistry and Cell Biology. 87:337-346
The genome is organized into nuclear domains, which create microenvironments that favor distinct chromatin structures and functions (e.g., highly repetitive sequences, centromeres, telomeres, noncoding sequences, inactive genes, RNA polymerase II and
Autor:
Annie D’AmoursA. D’Amours, Antonio Conconi, Frédéric Leduc, Guylain Boissonneault, François Peyresaubes, Marie-Chantal Grégoire
Publikováno v:
DNA repair. 36
A strategy amenable to the genome-wide study of DNA damage and repair kinetics is described. The ultraviolet damage endonuclease (UVDE) generates 3'-OH ends at the two major UV induced DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6,4 pyrimid