Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Annie Cunningham"'
Publikováno v:
Stem Cell Reports. 17:2585-2594
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b40bee573ef75a69b49bf0379ec8182c
https://doi.org/10.1016/j.stemcr.2022.10.006
https://doi.org/10.1016/j.stemcr.2022.10.006
Autor:
Dalip Sethi, Annie Cunningham
Publikováno v:
Cell and Gene Therapy Insights. 7:1163-1171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c74753488428ff70ddf31a43fc0b2be1
https://doi.org/10.18609/cgti.2021.158
https://doi.org/10.18609/cgti.2021.158
Autor:
Dalip Sethi, Annie Cunningham
Publikováno v:
Cell and Gene Therapy Insights. 6:1513-1519
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24807caa27388518f3b2363035e86826
https://doi.org/10.18609/cgti.2020.165
https://doi.org/10.18609/cgti.2020.165
Publikováno v:
Stem cell reports. 17(12)
Human leukocyte antigen (HLA)-matched cord blood (CB) transplantation is a procedure for the treatment of certain hematological malignancies, hemoglobinopathies, and autoimmune disorders. However, one of the challenges is to provide a sufficient numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b20574f7cc1d617fa2566e78106fda68
https://pubmed.ncbi.nlm.nih.gov/36332632
https://pubmed.ncbi.nlm.nih.gov/36332632
Autor:
Renate Kunert, Emil F. Pai, Steve Bryson, Jason Ho, Michèl R. Klein, Rosemary C. Hynes, Annie Cunningham, Hermann Katinger, Brian H. Barber, David E. Isenman
Publikováno v:
Protein & Peptide Letters. 8:413-418
The human monoclonal antibody 2F5 is a potent neutralizer of most clades of HIV-1 and possesses protective effects against viral transmission. It recognizes the linear epitope ELDKWAS of the viral envelope protein gp41. As structural information abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29452ea22ee02679847ce06483e34635
https://doi.org/10.2174/0929866013409201
https://doi.org/10.2174/0929866013409201
Autor:
Marlene Stubbs, Emil F. Pai, Michael Ward, Kenny Q.P. Ngo, Guang-Chou Tu, Theo Hofmann, Annie Cunningham, Qing-Na Cao
The nucleotide sequence of the gene (pepA) of a zymogen of an aspartic proteinase from Penicillium janthinellum with a 71% identity in the deduced amino acid sequence to penicillopepsin (which we propose to call penicillopepsin-JT1) has been determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9865d9c80504749ddd71edb751825021
https://europepmc.org/articles/PMC2144643/
https://europepmc.org/articles/PMC2144643/
Publikováno v:
The Journal of biological chemistry. 266(15)
Penicillopepsin acting on Nph-Ala2-amide (where Nph = p-nitrophenylalanyl) catalyzes a transpeptidation reaction which leads to the formation of Nph2-Ala2-amide, which arises from condensation of the substrate with enzyme-bound Nph, as the first prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1365be8c2764aa236edde1caf3da70
https://pubmed.ncbi.nlm.nih.gov/2033049
https://pubmed.ncbi.nlm.nih.gov/2033049
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781468460148
Several high resolution structures of aspartic proteinases are now known, (see Gilliland et al.1 for a recent list and earlier contributions in this volume) and detailed information has been obtained on the binding of substrate analogue inhibitors fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cfa0e91923e57dc841d52f7e31be768
https://doi.org/10.1007/978-1-4684-6012-4_28
https://doi.org/10.1007/978-1-4684-6012-4_28
Publikováno v:
The Journal of biological chemistry. 265(9)
The effect of temperature on the rate constants of hydrolysis of various substrates by penicillopepsin is dependent on the length of the substrate. For the series Ac-(Ala)m-Lys-Nph-(Ala)n-amide (where Ac- is acetyl- and Nph- is p-nitrophenylalanyl-),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc2e61c02cd81567ca8a8aade9aec71
https://pubmed.ncbi.nlm.nih.gov/2180955
https://pubmed.ncbi.nlm.nih.gov/2180955
Publikováno v:
Biochemistry. 27:1140-1146
The kinetic parameters kcat, KM, and kcat/KM were determined at 25 degrees C and pH 4.5, 5.5, and 6.0 for the series of penicillopepsin substrates Ac-Alam-Lys-(NO2)Phe-Alan-amide, where (NO2)Phe is p-nitrophenylalanine and m and n equal 0-3. KM value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b415e7eb6eea7654177d1494d2c5df5
https://doi.org/10.1021/bi00404a010
https://doi.org/10.1021/bi00404a010