Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Annie Buard"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 206-214 (2021)
Hydroquinone (HQ) exposure is common as it is a natural component of plant-based foods and is used in some fingernail polishes, hair dyes, and skin lighteners. Industrially it is used as an antioxidant, polymerization inhibitor, and reducing agent. T
Externí odkaz:
https://doaj.org/article/50aaf39f1075462aa6c5c43c80cb78ac
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 206-214 (2021)
Hydroquinone (HQ) exposure is common as it is a natural component of plant-based foods and is used in some fingernail polishes, hair dyes, and skin lighteners. Industrially it is used as an antioxidant, polymerization inhibitor, and reducing agent. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5274534a7654adceadb02f5ac4d7f82
http://www.sciencedirect.com/science/article/pii/S2214750021000056
http://www.sciencedirect.com/science/article/pii/S2214750021000056
Publikováno v:
Toxicology Reports
Highlights • Hydroquinone did not induce DNA strand breaks when tested in a Comet Assay. • Nephrotoxic doses of hydroquinone did not result in DNA strand breaks. • Exposure route differences in metabolism explain differences in Comet Assay resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::895351c7dfbb22e4705ec609e25ef745
https://pubmed.ncbi.nlm.nih.gov/33489780
https://pubmed.ncbi.nlm.nih.gov/33489780
Publikováno v:
Oncogene. 17:47-55
Our previous data demonstrated that Ras activation is necessary and sufficient for transforming growth factor beta (TGFbeta)-mediated Erk1 activation, and is partially required for the inhibition of cyclin-dependent kinase 2 (Cdk2) activity, cyclin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2e847383e40d5dfa13c2e180788c0e
https://doi.org/10.1038/sj.onc.1201903
https://doi.org/10.1038/sj.onc.1201903
Autor:
Kathleen M. Mulder, Melanie T. Hartsough, Patricia A. Zipfel, Frank McCormick, Randall S. Frey, Annie Buard, Simon J. Cook
Publikováno v:
Journal of Biological Chemistry. 271:22368-22375
We have previously demonstrated that growth inhibition of untransformed intestinal epithelial cells by transforming growth factor beta1 (TGFbeta) and TGFbeta2 was associated with a rapid activation of both Ras and extracellular signal-regulated kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7b62a023075bf4fd2a21a13eb87d37
https://doi.org/10.1074/jbc.271.37.22368
https://doi.org/10.1074/jbc.271.37.22368
Publikováno v:
International Journal of Cancer. 67:539-546
Fifty percent of human colon carcinomas contain activating mutations in the K-ras gene. However, whether these alterations in K-ras affect the function of Ras proteins in growth factor (GF) signal transduction is not known. Here we have characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec93db09f2e8fddf8adb636a1399dfe
https://doi.org/10.1002/(sici)1097-0215(19960807)67:4<539::aid-ijc13>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19960807)67:4<539::aid-ijc13>3.0.co
Autor:
Patrick Brochard, Jocelyne Fleury-Feith, Noureddine Trabelsi, P. Laurent, Jean-Claude Pairon, Annie Buard, Philippe Beaune, Claude-Marie Bachelet, Françoise Poron
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 11:386-396
In order to characterize the response of various pulmonary cell types to polycyclic aromatic hydrocarbons, the expression of cytochrome P450 (CYP) 1A1 and 2B1 mRNA in the lung of rats, with or without induction by 3-methylcholanthrene (3MC), was anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a238cfa9a5449b3e219c692b877ce9
https://doi.org/10.1165/ajrcmb.11.4.7917307
https://doi.org/10.1165/ajrcmb.11.4.7917307
Autor:
Philippe Beaune, Philippe Laurent, Annie Renier, Jean Bignon, Marie-Claude Jaurand, Annie Buard
Publikováno v:
Journal of Cellular Physiology. 160:176-184
Cultured rat pleural mesothelial cells (RPMC) isolated from male Sprague-Dawley rats have been shown to metabolize polycylic aromatic hydrocarbons to more oxygenated metabolites. This capacity, which is maintained with passages, suggested the presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd8d5e8a34d7e22483f1ceaccb222ec
https://doi.org/10.1002/jcp.1041600120
https://doi.org/10.1002/jcp.1041600120
Autor:
Annie Renier, Marie-Claude Jaurand, Laure Saint-Etienne, Annie Buard, Françoise Levy, Hang Ying Dong
Publikováno v:
Carcinogenesis. 15:1251-1255
The role of reactive oxygen metabolites in the toxic effects of asbestos on pleural mesothelial cells is not well defined. We exposed rat pleural mesothelial cells (RPMC) to chrysotile and crocidolite fibers (0-40 micrograms/cm2) in the presence or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ced5864b6eccb758d4720b391ee90ae
https://doi.org/10.1093/carcin/15.6.1251
https://doi.org/10.1093/carcin/15.6.1251
Autor:
I Monnet, Laure Saint-Etienne, Patrick Brochard, Jocelyne Fleury, Annie Buard, J Bignon, C. Boutin, Marie-Claude Jaurand, L Zeng
Publikováno v:
International Journal of Cancer. 55:515-520
Malignant mesothelioma is a tumor arising from serous surfaces and often related to asbestos exposure. Malignant mesothelioma is resistant to various forms of therapy. Radiotherapy, surgery or chemotherapy only slightly improve prognosis. IFN-gamma p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b830268c750a4e66e937fd934cd8b1
https://doi.org/10.1002/ijc.2910550331
https://doi.org/10.1002/ijc.2910550331