Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annie, Maslan"'
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103772- (2022)
Summary: All-trans retinoic acid (ATRA) is an essential therapy in the treatment of acute promyelocytic leukemia (APL), but nearly 20% of patients with APL are resistant to ATRA. As there are no biomarkers for ATRA resistance that yet exist, we inves
Externí odkaz:
https://doaj.org/article/2841ba555add4e0091d595e04d74d677
Autor:
Annie Maslan, Nicolas Altemose, Reet Mishra, Jeremy Marcus, Lucy D. Brennan, Kousik Sundararajan, Gary Karpen, Aaron F. Straight, Aaron Streets
We recently developed Directed Methylation with Long-read sequencing (DiMeLo-seq) to map protein-DNA interactions genome wide. DiMeLo-seq maps multiple interaction sites on single DNA molecules, profiles protein binding in the context of endogenous D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffde2d435dc5293faeba9f1a4dceadf9
https://doi.org/10.1101/2022.07.03.498618
https://doi.org/10.1101/2022.07.03.498618
Publikováno v:
Neuromethods ISBN: 9781071625248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529bd9ac61de3acb9d77ab9dd21b8a42
https://doi.org/10.1007/978-1-0716-2525-5_4
https://doi.org/10.1007/978-1-0716-2525-5_4
Autor:
Nicolas, Altemose, Annie, Maslan, Owen K, Smith, Kousik, Sundararajan, Rachel R, Brown, Reet, Mishra, Angela M, Detweiler, Norma, Neff, Karen H, Miga, Aaron F, Straight, Aaron, Streets
Publikováno v:
Nature methods. 19(6)
Studies of genome regulation routinely use high-throughput DNA sequencing approaches to determine where specific proteins interact with DNA, and they rely on DNA amplification and short-read sequencing, limiting their quantitative application in comp
Autor:
Annie Maslan, Kousik Sundararajan, Neff N, Owen K. Smith, Brown Rr, Detweiler Am, Aaron F. Straight, Aaron M. Streets, Karen H. Miga, Nicolas Altemose
Molecular studies of genome regulation often rely on the ability to map where specific proteins interact with genomic DNA. Existing techniques for mapping protein-DNA interactions genome-wide rely on DNA amplification methods followed by sequencing w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d3366be55442971dc7511aff285409
https://doi.org/10.1101/2021.07.06.451383
https://doi.org/10.1101/2021.07.06.451383
While all-trans retinoic acid (ATRA) is an essential therapy in the treatment of acute promyelocytic leukemia (APL), an aggressive subtype of acute myeloid leukemia, nearly 20% of APL patients are resistant to ATRA. As no biomarkers for ATRA resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78a092ff17657ddbe355c2a0b989036
https://doi.org/10.1101/2021.04.25.441378
https://doi.org/10.1101/2021.04.25.441378
Autor:
Andre Lai, Carolina Rios-Martinez, Annie Maslan, Jonathan A. White, Nicolas Altemose, Aaron M. Streets
Publikováno v:
Cell systems, vol 11, iss 4
Cell systems
Cell systems
SUMMARY DNA adenine methyltransferase identification (DamID) measures a protein’s DNA-binding history by methylating adenine bases near each protein-DNA interaction site and then selectively amplifying and sequencing these methylated regions. Addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52862ac415058a4d9d226491526fbd9
https://escholarship.org/uc/item/55v2f58f
https://escholarship.org/uc/item/55v2f58f
Autor:
Kanwal Pratap Singh Raghav, Shadarra Crosby, Yun Shin Chun, Allan Andresson Lima Pereira, Michael J. Overman, Van K. Morris, Jean Nicolas Vauthey, Stefanie Mortimer, Michelle Tan, Scott Kopetz, Zhi-Qin Jiang, Claudius Conrad, Steven H. Wei, Annie Maslan, AmirAli Talasaz, Thomas A. Aloia
Publikováno v:
Journal of Clinical Oncology. 35:3522-3522
3522 Background: Preliminary data suggests that ctDNA can serve as a marker of minimal residual disease following colorectal cancer (CRC) tumor resection. Applicability of current ctDNA testing is limited by the requirement of sequencing known indivi
Autor:
Stefanie Mortimer, Narsi Rajagopalan, Annie Maslan, Darya Chudova, Se-Hoon Lee, Hee Cheol Kim, AmirAli Talasaz, Michelle Tan, Ariel Jaimovich, Helmy Eltoukhy, Jhingook Kim, Seung Tae Kim, Drew Kennedy, Jeeyun Lee
Publikováno v:
Journal of Clinical Oncology. 35:e23068-e23068
e23068 Background: Analysis of cell-free circulating tumor DNA (ctDNA) by next-generation sequencing (NGS) is a promising method for detecting and monitoring earlier stage cancers. Liquid biopsies have a large potential to detect cancer earlier upon