Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Annie, Leung"'
Autor:
Gabriel Levin, Lucy Gilbert, Shuk On Annie Leung, Xing Zeng, Victoria Mandilaras, Laurence Bernard
Publikováno v:
Gynecologic Oncology Reports, Vol 55, Iss , Pp 101497- (2024)
Uterine leiomyosarcoma (LMS) represents a rare yet highly aggressive tumor, comprising approximately 1% of uterine malignancies. First-line regimens involving doxorubicin or gemcitabine and docetaxel demonstrate modest response rates. Notably, the co
Externí odkaz:
https://doaj.org/article/1709634e77b043d4b915aee85d07db77
Autor:
Emilie Wong Chong, France-Hélène Joncas, Pierre Douville, Dimcho Bachvarov, Caroline Diorio, Frédéric Calon, Ann-Charlotte Bergeron, Jonatan Blais, Shuk On Annie Leung, Nabil Georges Seidah, Anne Gangloff
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Cancer cells need constant supplies of lipids to survive and grow. Lipid dependence has been observed in various types of cancer, including high-grade serous ovarian carcinomas (HGSOC), which is a lethal form of gynecological malignancy. ANG
Externí odkaz:
https://doaj.org/article/3e08325700c543e7b2a228d6e9b32a33
Autor:
Naya El Mokbel, Alicia A. Goyeneche, Rewati Prakash, Benjamin N. Forgie, Farah H. Abdalbari, Xing Zeng, Basile Tessier-Cloutier, Shuk On Annie Leung, Carlos M. Telleria
Publikováno v:
Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101838- (2024)
High-grade serous cancer is the most common type of ovarian cancer and is usually diagnosed at advanced stages with high mortality due to recurrence and eventual resistance to standard platinum therapy. The aim of this study was to compare two-dimens
Externí odkaz:
https://doaj.org/article/700bf3ed34844eb6b08df2d216c52d67
Autor:
Hao-Chi Hsu, Daqiang Li, Wenhu Zhan, Jianxiang Ye, Yi Jing Liu, Annie Leung, Junling Qin, Benigno Crespo, Francisco-Javier Gamo, Hao Zhang, Liwang Cui, Alison Roth, Laura A. Kirkman, Huilin Li, Gang Lin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The proteasome of the malaria parasite Plasmodium falciparum (Pf20S) is an advantageous drug target because its inhibition kills P. falciparum in multiple stages of its life cycle and synergizes with artemisinins. We recently developed a mac
Externí odkaz:
https://doaj.org/article/c572579ac9434308b55f8122c4687613
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8386-8400 (2023)
Cholesterol plays an essential role in maintaining the rigidity of cell membranes and signal transduction. Various investigations confirmed empirically that the dysregulation of cholesterol homeostasis positively correlates with tumor progression. Mo
Externí odkaz:
https://doaj.org/article/6b519b037b514ed797ed937386d04022
Autor:
Rebecca Luckett, Sarah Feldman, Yin Ling Woo, Anna-Barbara Moscicki, Anna R Giuliano, Silvia de Sanjosé, Andreas M Kaufmann, Shuk On Annie Leung, Francisco Garcia, Karen Chan, Neerja Bhatla, Margaret Stanley, Julia Brotherton, Joel Palefsky, Suzanne Garland, on behalf of the International Papillomavirus Society (IPVS) Policy Committee
Publikováno v:
eLife, Vol 12 (2023)
Cervical cancer has killed millions of women over the past decade. In 2019 the World Health Organization launched the Cervical Cancer Elimination Strategy, which included ambitious targets for vaccination, screening, and treatment. The COVID-19 pande
Externí odkaz:
https://doaj.org/article/ced84400857e424aa23b1369c64aa443
Publikováno v:
IDCases, Vol 27, Iss , Pp e01460- (2022)
Tafenoquine is a highly effective treatment for Babesia microti infections in animal models. An immunocompromised patient infected by a strain of B. microti that was at least partially resistant to both azithromycin and atovaquone was treated with ta
Externí odkaz:
https://doaj.org/article/1489dfd117354062b58ef823b87a2739
Akademický článek
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Autor:
Yusheng Zhu, Sarah Feldman, Shuk On Annie Leung, Michael H Creer, Joshua Warrick, Nicole Williams, Stephen Mastorides
Publikováno v:
The Journal of Applied Laboratory Medicine. 8:382-406
Background Persistent genital infection with high-risk human papilloma virus (hrHPV) causes the vast majority of cases of cervical cancer. Early screening, ongoing surveillance, and accurate diagnosis are crucial for the elimination of cervical cance
Autor:
Hao Zhang, John Ginn, Wenhu Zhan, Annie Leung, Yi J. Liu, Akinori Toita, Rei Okamoto, Tzu-Tshin Wong, Toshihiro Imaeda, Ryoma Hara, Mayako Michino, Takafumi Yukawa, Sevil Chelebieva, Patrick K. Tumwebaze, Jeremie Vendome, Thijs Beuming, Kenjiro Sato, Kazuyoshi Aso, Philip J. Rosenthal, Roland A. Cooper, Nigel Liverton, Michael Foley, Peter T. Meinke, Carl F. Nathan, Laura A. Kirkman, Gang Lin
Publikováno v:
Journal of Medicinal Chemistry. 66:1484-1508