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pro vyhledávání: '"Annick van Nunen"'
Autor:
Debbie S. Deben, Luc J. J. Derijks, Bianca J. C. van den Bosch, Rob H. Creemers, Annick van Nunen, Adriaan A. van Bodegraven, Dennis R. Wong
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1054 (2023)
Tioguanine is metabolised by fewer enzymatic steps compared to azathioprine and mercaptopurine, without generating 6-methylmercaptopurine ribonucleotides. However, thiopurine S-methyl transferase (TPMT) plays a role in early toxicity in all thiopurin
Externí odkaz:
https://doaj.org/article/5fbf9405476044e988f385599d3ddcd0
