Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.

Autor: Robin Cloarec, Sylvian Bauer, Hervé Luche, Emmanuelle Buhler, Emilie Pallesi-Pocachard, Manal Salmi, Sandra Courtens, Annick Massacrier, Pierre Grenot, Natacha Teissier, Françoise Watrin, Fabienne Schaller, Homa Adle-Biassette, Pierre Gressens, Marie Malissen, Thomas Stamminger, Daniel N Streblow, Nadine Bruneau, Pierre Szepetowski

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0160176 (2016)

Congenital cytomegalovirus infections are a leading cause of neurodevelopmental disorders in human and represent a major health care and socio-economical burden. In contrast with this medical importance, the pathophysiological events remain poorly kn

Externí odkaz: https://doaj.org/article/371226e8d6c4478288cb0926fc420cb7

Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation

Autor: Pierre Gressens, Fabienne Schaller, Pierre Grenot, Marie Malissen, Natacha Teissier, Manal Salmi, Nadine Bruneau, Emilie Pallesi-Pocachard, Sylvian Bauer, Pierre Szepetowski, Thomas Stamminger, Hervé Luche, Emmanuelle Buhler, Robin Cloarec, Daniel N. Streblow, Sandra Courtens, Annick Massacrier, Homa Adle-Biassette, Françoise Watrin

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2016, 11 (7), ⟨10.1371/journal.pone.0160176⟩
PLoS ONE, 2016, 11 (7), ⟨10.1371/journal.pone.0160176⟩
Cloarec, R, Bauer, S, Luche, H, Buhler, E, Pallesi-Pocachard, E, Salmi, M, Courtens, S, Massacrier, A, Grenot, P, Teissier, N, Watrin, F, Schaller, F, Adle-Biassette, H, Gressens, P, Malissen, M, Stamminger, T, Streblow, D N, Bruneau, N & Szepetowski, P 2016, ' Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation ', PLoS ONE, vol. 11, no. 7, e0160176 . https://doi.org/10.1371/journal.pone.0160176
PLoS ONE, Vol 11, Iss 7, p e0160176 (2016)

International audience; Background Congenital cytomegalovirus infections are a leading cause of neurodevelopmental disorders in human and represent a major health care and socio-economical burden. In contrast with this medical importance, the pathoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adcdb5229d94a214f46b22c28754def
https://opus4.kobv.de/opus4-fau/files/7324/Cloarec_cytomegalovirus.pdf

ARP3β, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells

Autor: Maximilian Muenke, Pierre Cau, Marguerite Gastaldi, Erich Roessler, Jean-Louis Bergé-Lefranc, Philippe Berta, Annick Massacrier, Sylvie Taviaux, Philippe Jay, Deeann Wallis

Publikováno v: European Journal of Biochemistry. 267:2921-2928

A cDNA encoding a new human actin-related protein (ARP) was cloned. The corresponding protein is highly conserved with the previously described ARP3 protein, suggesting that it represents a second isoform of the human ARP3 subfamily. This new actin-r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f0bfee53c046af0434ba4631b64ce01
https://doi.org/10.1046/j.1432-1327.2000.01306.x

mRNA coding for voltage-gated sodium channel β2 subunit in rat central nervous system: cellular distribution and changes following kainate-induced seizures

Autor: Andrée Robaglia-Schlupp, Annick Massacrier, Richard Planells, Marguerite Gastaldi, Pierre Cau

Publikováno v: Neuroscience Letters. 249:53-56

The cellular distribution of sodium channel beta2 subunit mRNA was examined in the central nervous system from adult Wistar rats using a non-radioactive in situ hybridization method with digoxigenin-labeled cRNA probes. The expression of the subunit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51c81acbcf4640f95ce2364315bdcd
https://doi.org/10.1016/s0304-3940(98)00394-2

Tubacin prevents neuronal migration defects and epileptic activity caused by rat Srpx2 silencing in utero

Autor: Carlos Cardoso, Nadine Bruneau, Vera Tsintsadze, Nail Burnashev, Annick Massacrier, Yehezkel Ben-Ari, Manal Salmi, Ilgam Khalilov, Daniel Lafitte, Claude Villard, Jennifer Cillario, Robin Cloarec, Françoise Watrin, Gabrielle Rudolf, Pascale Durbec, Natalia Lozovaya, Françoise Muscatelli, Lan Bao, Pierre Szepetowski, Vanessa Pauly, Gaetan Lesca, Céline Zimmer, Emmanuelle Buhler, Timur Tsintsadze, Alfonso Represa

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2013, 136 (Pt 8), pp.2457-73. ⟨10.1093/brain/awt161⟩
Brain-A Journal of Neurology, 2013, 136 (8), pp.2457-2473. ⟨10.1093/brain/awt161⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2013, 136 (8), pp.2457-2473. ⟨10.1093/brain/awt161⟩
Brain-A Journal of Neurology, 2013, 136 (Pt 8), pp.2457-73. ⟨10.1093/brain/awt161⟩

International audience; Altered development of the human cerebral cortex can cause severe malformations with often intractable focal epileptic seizures and may participate in common pathologies, notably epilepsy. This raises important conceptual and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb2f021df909c0836b616ca4f791fc6
https://hal.archives-ouvertes.fr/hal-00862156