Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annick, Prenez"'
Publikováno v:
Toxicologic Pathology. 32:202-211
The topical administration of 7H-dibenzo[c,g]carbazole (7H-DBC) at very low but repeated doses causes genotoxic effects such as DNA adduct formation and produces hepatocellular apoptosis in mouse liver. The purpose of this work was to investigate the
Autor:
Joan-Albert Vericat, Odette Périn-Roussel, Olivier Dorchies, Olivier Gillardeaux, François Périn, Nigel Roome, Annick Prenez
Publikováno v:
Toxicologic Pathology. 29:528-534
The purpose of this work was to investigate the administration of very low but repeated doses of a genotoxic carcinogen and an eventual correlation with cellular DNA synthesis. The compound 7H-dibenzo[c,g]carbazole is a genotoxic carcinogen in the mo
Autor:
Nicolas, Fabre, Elsa, Arrivet, Françoise, Paillard, Valérie, Wibaut-Berlaimont, Nicole, Bichet, Nigel O, Roome, Annick, Prenez, Joan-Albert, Vericat
Publikováno v:
Alternatives to laboratory animals : ATLA. 32
Early toxicity screening of new drugs is performed to select candidates for development. Many cell models are used to assess basic cytotoxicity and to show a good correlation with acute toxicity. However, their correlation with chronic in vivo exposu