Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection

Autor: Winke Van der Gucht, Annelies Leemans, Marjorie De Schryver, Annick Heykers, Guy Caljon, Louis Maes, Paul Cos, Peter L. Delputte

Publikováno v: Virology Journal, Vol 14, Iss 1, Pp 1-10 (2017)

Abstract Background Host proteases have been shown to play important roles in many viral activities such as entry, uncoating, viral protein production and disease induction. Therefore, these cellular proteases are putative targets for the development

Externí odkaz: https://doaj.org/article/b101576381be4b3287a87728954c33e7

Differences in Susceptibility of Human and Mouse Macrophage Cell Lines to Respiratory Syncytial Virus Infection

Autor: Paul Cos, Peter Delputte, Annick Heykers, Winke Van der Gucht, Annelies Leemans, Marjorie De Schryver

Publikováno v: Intervirology

Objectives: Differences have been observed in the susceptibility of macrophage cell lines to respiratory syncytial virus (RSV) infection. In this study, we evaluated whether the type of macrophage cell line and RSV strain used have an influence on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76626689f586783afab04967da872025
https://doi.org/10.1159/000502674

Differential Induction Pattern Towards Classically Activated Macrophages in Response to an Immunomodulatory Extract from Pleurotus ostreatus Mycelium

Autor: Peter Delputte, Annick Heykers, Zelene Salgueiro, Paul Cos, Humberto J Morris-Quevedo, Ellen Lanckacker, Davie Cappoen, Wim Vanden Berghe, Gabriel Llauradó Maury

Publikováno v: Journal of Fungi
Volume 7
Issue 3
Journal of Fungi, Vol 7, Iss 206, p 206 (2021)

Pleurotus ostreatus mushroom preparations have been investigated because of their ability to modulate the immune function. However, there is still no consensus regarding the activation and polarizing effect on macrophages by Pleurotus-derived bioprod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2cd7a082a52e623057161c71dbe332

Antibody-induced internalization of the human respiratory syncytial virus fusion protein

Autor: Alexander Leemans, Barney S. Graham, Annick Heykers, Ultan F. Power, Isabel Pintelon, Jason S. McLellan, Paul Cos, Lindsay Broadbent, M De Schryver, Peter Delputte, Martin L. Moore, Guy Caljon, W Van der Gucht, Louis Maes, Anne L. Hotard, J A Melero

Publikováno v: Leemans, A, De Schryver, M, Van der Gucht, W, Heykers, A, Pintelon, I, Hotard, A L, Moore, M L, Melero, J A, McLellan, J S, Graham, B, Broadbent, L, Power, U F, Caljon, G, Cos, P, Maes, L & Delputte, P 2017, ' Antibody-induced internalization of the human respiratory syncytial virus fusion protein ', Journal of Virology . https://doi.org/10.1128/JVI.00184-17
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Journal of virology

Respiratory syncytial virus (RSV) infections remain a major cause of respiratory disease and hospitalizations among infants. Infection recurs frequently and establishes a weak and short-lived immunity. To date, RSV immunoprophylaxis and vaccine resea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb7265ae81afdef564c7fb89d772b31
https://pure.qub.ac.uk/en/publications/d2e74556-d653-4964-9092-aad2b6e4b107

Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense

Autor: Nicolas Bebronne, Magali Meul, Annick Heykers, Annette Brouwer de Koning, Stijn Rogé, Liesbeth Van Nieuwenhove, Philippe Büscher, Yves Guisez

Publikováno v: PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e3006 (2014)
PLoS Neglected Tropical Diseases
PLoS neglected tropical diseases

Background Screening tests for gambiense sleeping sickness, such as the CATT/T. b. gambiense and a recently developed lateral flow tests, are hitherto based on native variant surface glycoproteins (VSGs), namely LiTat 1.3 and LiTat 1.5, purified from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2ad50c9b8551ca109b36b87e1056b4
http://europepmc.org/articles/PMC4102443?pdf=render