Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Annibal P. Campello"'
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 55, Iss 2, Pp 249-257 (1997)
Foi determinada a atividade das enzimas NADH desidiogenase, NADH citocromo e redutase, succinato desidiogenase, succinato citocromo e redutase, citocromo e oxidase e citrato sintase em mitocôndrias de músculo esquelético humano normal e doente (su
Externí odkaz:
https://doaj.org/article/99872b3cfb3942338d948fb3237274e3
Autor:
Eva Gunilla Skare Carnieri, Annibal P. Campello, Regina Maria V. Babiak, Ma. Benigna M. Oliveira
Publikováno v:
Cell Biochemistry and Function. 16:283-293
The effect of methotrexate (MTX) and leucovorin (LCV) on pentose cycle enzymes and the activity of enzymes involved in enzyme defence mechanisms against ROS in HeLa cells, were studied. The effect of MTX was also investigated on the cellular levels o
Autor:
Annibal P. Campello, Maria Benigna M. Oliveira, Roberto F. Melo, Eva Gunilla Skare Carnieri, Fabiola R. Stevan
Publikováno v:
Cell Biochemistry and Function. 16:99-105
The occurrence of a Crabtree effect in HeLa cells was detected. Some properties of pyruvate kinase (PK) were also evaluated. Hexose phosphate, triose-phosphate and phosphoenolpyruvate (PEP) significantly decreased the oxygen consumption of digitonin-
Publikováno v:
Cell Biochemistry and Function. 16:15-20
The inhibition by citrinin (CTN) of lipid peroxidation of mitochondria, sub-mitochondrial particles (SMP) and microsomes was studied. This effect was reversed by the presence of high concentrations of Fe3+ (0·4 and 0·5 mM), suggesting chelation of
Autor:
Annibal P. Campello, Maria Benigna M. Oliveira, M. L. W. Kluppel, Nilce N. Caetano, Eva Gunilla Skare Carnieri
Publikováno v:
Cell Biochemistry and Function. 15:259-264
The effects of methotrexate (MTX) on oxygen uptake by permeabilized HeLa cells were evaluated. MTX did not inhibit state III respiration when the oxidizable substrate was succinate, but when the substrates were 2-oxoglutarate or isocitrate the respir
Publikováno v:
Cell Biochemistry and Function. 15:203-209
The effects of citrinin in the maintenance of the homeostasis of the reactive oxygen species in rat liver cells were evaluated. Citrinin (CTN) modifies the antioxidant enzymatic defences of cells through the inhibition of GSSG-reductase and transhydr
Publikováno v:
Cell Biochemistry and Function. 15:145-152
The effects of amiodarone (AMD) on lipid peroxidation of rat liver mitochondria, the formation of superoxide anions at the respiratory chain level, and the cytosolic and mitochondrial enzymatic protective mechanisms of oxidative stress were studied.
Publikováno v:
Cell Biochemistry and Function. 13:267-271
The effects of citrinin on energy production along the respiratory chain and on glycolytic lactate production were examined in BHK-21 cultured cells. Citrinin inhibited the oxygen consumption rate by about 45 per cent. The respiratory rate of digiton
Publikováno v:
Cell Biochemistry and Function. 13:53-59
The effect of citrinin on Ca2+ transport was studied in isolated kidney cortex and liver mitochondria, and baby hamster kidney cultured cells. The mycotoxin significantly inhibited the activity of 2-oxoglutarate and pyruvate dehydrogenases in both ki
Publikováno v:
Journal of Applied Toxicology. 14:21-26
Tordon herbicide, which is a mixture of 4-amino-3,5,6-trichloropicolinic acid (picloram) and 2,4-dichlorophenoxyacetic acid (2,4-D), depresses the phosphorylation efficiency of the rat liver mitochondria, as inferred from the decrease of the respirat