Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

Autor: John P. Overington, Prson Gautam, Balaguru Ravikumar, Markus Vähä-Koskela, Abhishekh Gupta, Alok Jaiswal, Liye He, Suleiman A. Khan, Gopal Peddinti, Brinton Seashore-Ludlow, Andrew R. Leach, Laxman Yetukuri, Zaid Alam, Mehreen Ali, Arjan J. van Adrichem, Gretchen A. Repasky, Elina Parri, Krister Wennerberg, Anne Hersey, Anna-Lena Gustavsson, Ella Karjalainen, Tero Aittokallio, Anni Rebane, Ziaurrehman Tanoli, Janica Wakkinen, Jing Tang

Publikováno v: Cell Chemical Biology
Tang, J, Tanoli, Z-R, Ravikumar, B, Alam, Z, Vähä-Koskela, M, Peddinti, G, van Adrichem, A J, Wakkinen, J, Jaiswal, A, Karjalainen, E, Gautam, P, He, L, Parri, E, Khan, S, Gupta, A, Ali, M, Yetukuri, L, Gustavsson, A-L, Seashore-Ludlow, B, Hersey, A, Leach, A R, Overington, J P, Repasky, G, Wennerberg, K & Aittokallio, T 2018, ' Drug Target Commons : A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions ', Cell Chemical Biology, vol. 25, no. 2, pp. 224-229.e2 . https://doi.org/10.1016/j.chembiol.2017.11.009

Summary Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights into therapeutic potential and possible adverse effects. The existing compound-target bioac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1d56d48f461d6982610f3ce4bc2159
https://doi.org/10.1016/j.chembiol.2017.11.009