Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anni Laine"'
Autor:
Kevin Myant, Xi Qiao, Tuuli Halonen, Christophe Come, Anni Laine, Mahnaz Janghorban, Johanna I. Partanen, John Cassidy, Erinn-Lee Ogg, Patrizia Cammareri, Tiina Laiterä, Juha Okkeri, Juha Klefström, Rosalie C. Sears, Owen J. Sansom, Jukka Westermarck
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 1019-1031 (2015)
An understanding of the mechanisms determining MYC’s transcriptional and proliferation-promoting activities in vivo could facilitate approaches for MYC targeting. However, post-translational mechanisms that control MYC function in vivo are poorly u
Externí odkaz:
https://doaj.org/article/9192a9a0cda04901aa08c766517eccaa
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Methods PDF file - 98K, Supplementary materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b336bf17687355e01489a662d554db2c
https://doi.org/10.1158/2159-8290.22528874.v1
https://doi.org/10.1158/2159-8290.22528874.v1
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Table S2 PDF file - 90K, Ingenuity transcription factor analysis of CIP2A depleted cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb9b095ad23d8e322b131468a30db37
https://doi.org/10.1158/2159-8290.22528868.v1
https://doi.org/10.1158/2159-8290.22528868.v1
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Figure 5 PDF file - 82K, Prognostic value of CIP2A in advanced human breast cancer patient material and characterization of vinorelbine effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2a364c9a372fc93d27a352cf7e2bb2
https://doi.org/10.1158/2159-8290.22528877
https://doi.org/10.1158/2159-8290.22528877
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Figure 4 PDF file - 269K, Characterization of hypomorphic CIP2A HOZ mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55ac479cc37d3475daeeec42b6a8e38
https://doi.org/10.1158/2159-8290.22528880.v1
https://doi.org/10.1158/2159-8290.22528880.v1
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Figure 3 PDF file - 114K, RB expression is not needed for CIP2A-depletion induced senescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486071acf678e3805c39ff715aa33381
https://doi.org/10.1158/2159-8290.22528883
https://doi.org/10.1158/2159-8290.22528883
Autor:
Jukka Westermarck, Heikki Joensuu, Jean-Christophe Marine, Kevin M. Ryan, Melissa R. Junttila, Gerard I. Evan, Owen J. Sansom, Pirkko-Liisa Kellokumpu-Lehtinen, Veli-Matti Kähäri, Edward K. Chan, Anchit Khanna, Minna Niemelä, Aleksandra Zwolinska, Mathias T. Rosenfeldt, Christophe Come, Harri Sihto, Anni Laine
Supplementary Figure 2 PDF file - 96K, Transcriptional regulation and functional role for CIP2A in response to p53 reactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3f6f3580d922ab244744bead83a90f
https://doi.org/10.1158/2159-8290.22528886
https://doi.org/10.1158/2159-8290.22528886
Autor:
Jukka Westermarck, Simon Thézenas, Olli Kallioniemi, Jean-Marie Darbon, Jorma Isola, Johanna Ivaska, Jos Jonkers, Xiaoling Liu, Elina Mattila, Henrik Edgren, Maïa Chanrion, Anni Laine, Christophe Côme
Supplementary Data from CIP2A Is Associated with Human Breast Cancer Aggressivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1207dd3cca17ae6fe1fc2d73a07b3c88
https://doi.org/10.1158/1078-0432.22440628.v1
https://doi.org/10.1158/1078-0432.22440628.v1
Autor:
Jukka Westermarck, Simon Thézenas, Olli Kallioniemi, Jean-Marie Darbon, Jorma Isola, Johanna Ivaska, Jos Jonkers, Xiaoling Liu, Elina Mattila, Henrik Edgren, Maïa Chanrion, Anni Laine, Christophe Côme
Purpose: To investigate the clinical relevance of the recently characterized human oncoprotein cancerous inhibitor of protein phosphatase 2A (CIP2A) in human breast cancer.Experimental Design: CIP2A expression (mRNA and protein) was measured in three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1852f710829132c0ebaf02b65be784e2
https://doi.org/10.1158/1078-0432.c.6517930
https://doi.org/10.1158/1078-0432.c.6517930
Autor:
Jukka Westermarck, Goutham Narla, Karin de Visser, Emilia Peuhu, Heikki Joensuu, Rene H. Medema, Krister Wennerberg, Jochen Maurer, Laura L. Elo, Pauliina Kronqvist, Denise C. Connolly, Karolina Pavic, Xi Qiao, Harri Sihto, Sofia Khan, Prson Gautam, Tove J. Grönroos, Femke M. Feringa, Julia P. Vainonen, Anna N. Cvrljevic, Umar Butt, Caroline Farrington, Srikar G. Nagelli, Anni Laine
Basal-like breast cancers (BLBC) are characterized by defects in homologous recombination (HR), deficient mitotic checkpoint, and high-proliferation activity. Here, we discover CIP2A as a candidate driver of BLBC. CIP2A was essential for DNA damage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58953009a86d62cede066667426b4c40
https://doi.org/10.1158/0008-5472.c.6513027
https://doi.org/10.1158/0008-5472.c.6513027