Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anni Allikalt"'
Autor:
Anni Allikalt, Nirupam Purkayastha, Khajidmaa Flad, Maximilian F. Schmidt, Alina Tabor, Peter Gmeiner, Harald Hübner, Dorothee Weikert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Fluorescent ligands are versatile tools for the study of G protein-coupled receptors. Depending on the fluorophore, they can be used for a range of different applications, including fluorescence microscopy and bioluminescence or fluorescence
Externí odkaz:
https://doaj.org/article/917ec5091e204abdb7245329c218d9c8
Autor:
Triin Tekko, Triin Lakspere, Anni Allikalt, Jaanus End, Karl Rene Kõlvart, Toomas Jagomäe, Anton Terasmaa, Mari-Anne Philips, Tanel Visnapuu, Fred Väärtnõu, Scott F Gilbert, Ago Rinken, Eero Vasar, Kersti Lilleväli
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172825 (2017)
During amniote evolution, the construction of the forebrain has diverged across different lineages, and accompanying the structural changes, functional diversification of the homologous brain regions has occurred. This can be assessed by studying the
Externí odkaz:
https://doaj.org/article/dae4c43a360a4944b2752ae1706653c8
Publikováno v:
The FEBS Journal. 288:1514-1532
Dopamine receptors are G protein-coupled receptors that have several essential functions in the central nervous system. A better understanding of the regulatory mechanisms of ligand binding to the receptor may open new possibilities to affect the dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5cfdaf4767faec0540f3cb14ba34ea
https://doi.org/10.1111/febs.15519
https://doi.org/10.1111/febs.15519
Autor:
Darja, Lavogina, Tõnis, Laasfeld, Maris-Johanna, Tahk, Olga, Kukk, Anni, Allikalt, Sergei, Kopanchuk, Ago, Rinken
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2268
Cyclic adenosine monophosphate (cAMP) serves as a second messenger for numerous G-protein-coupled receptors. Changes in cellular cAMP levels reflect the biological activity of various GPCR-specific agents, including protein hormones. cAMP biosensors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::306ba4268aed541261c0b25aacd5d713
https://pubmed.ncbi.nlm.nih.gov/34085269
https://pubmed.ncbi.nlm.nih.gov/34085269
Publikováno v:
International Journal of Molecular Sciences
The human dopamine receptors D2S and D3 belong to the group of G protein-coupled receptors (GPCRs) and are important drug targets. Structural analyses and development of new receptor subtype specific drugs have been impeded by low expression yields o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::690fd1898b5f7a9a941f9a212ca32f42
https://pubmed.ncbi.nlm.nih.gov/34445358
https://pubmed.ncbi.nlm.nih.gov/34445358
Autor:
Sergei Kopanchuk, Tõnis Laasfeld, Ago Rinken, Maris-Johanna Tahk, Darja Lavogina, Anni Allikalt, Olga Kukk
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612200
Cyclic adenosine monophosphate (cAMP) serves as a second messenger for numerous G-protein-coupled receptors. Changes in cellular cAMP levels reflect the biological activity of various GPCR-specific agents, including protein hormones. cAMP biosensors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce990eb7f6da83fdbfed56b14680ae9
https://doi.org/10.1007/978-1-0716-1221-7_12
https://doi.org/10.1007/978-1-0716-1221-7_12
Autor:
Lukas, Grätz, Tõnis, Laasfeld, Anni, Allikalt, Corinna G, Gruber, Andrea, Pegoli, Maris-Johanna, Tahk, Mari-Liis, Tsernant, Max, Keller, Ago, Rinken
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1868(3)
BRET and fluorescence anisotropy (FA) are two fluorescence-based techniques used for the characterization of ligand binding to G protein-coupled receptors (GPCRs) and both allow monitoring of ligand binding in real time. In this study, we present the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a0824993309d9c4e35251a8cf2eed84
https://pubmed.ncbi.nlm.nih.gov/33347921
https://pubmed.ncbi.nlm.nih.gov/33347921
Publikováno v:
The FEBS journalReferences. 288(5)
Dopamine receptors are G protein-coupled receptors that have several essential functions in the central nervous system. A better understanding of the regulatory mechanisms of ligand binding to the receptor may open new possibilities to affect the dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a84ff1cd3e878b0b362d0f828ddcc09
https://pubmed.ncbi.nlm.nih.gov/32783364
https://pubmed.ncbi.nlm.nih.gov/32783364
Publikováno v:
European Journal of Pharmacology. 839:40-46
Dopamine receptors, which belong to the family of G protein-coupled receptors, are very substantial regulators in the brain and therefore important targets in drug discovery. Radioligand binding assay has been the method of choice for screening novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3ad42d6eb71cb82fd6d6cd6c783a436
https://doi.org/10.1016/j.ejphar.2018.09.008
https://doi.org/10.1016/j.ejphar.2018.09.008
Autor:
Anni Allikalt, Ago Rinken
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 86:81-86
Introduction G-protein-coupled receptors have become very important drug targets and therefore ligand binding assays for these receptors are an essential part of drug discovery. Among a variety of experimental systems, the radioligand binding assay h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3ed43f4cbc87ff35c9b7c239afa8f1a
https://doi.org/10.1016/j.vascn.2017.04.004
https://doi.org/10.1016/j.vascn.2017.04.004