Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Annette W. Fothergill"'
Autor:
Visesato Mor, Antonella Rella, Amir M. Farnoud, Ashutosh Singh, Mansa Munshi, Arielle Bryan, Shamoon Naseem, James B. Konopka, Iwao Ojima, Erika Bullesbach, Alan Ashbaugh, Michael J. Linke, Melanie Cushion, Margaret Collins, Hari Krishna Ananthula, Larry Sallans, Pankaj B. Desai, Nathan P. Wiederhold, Annette W. Fothergill, William R. Kirkpatrick, Thomas Patterson, Lai Hong Wong, Sunita Sinha, Guri Giaever, Corey Nislow, Patrick Flaherty, Xuewen Pan, Gabriele Vargas Cesar, Patricia de Melo Tavares, Susana Frases, Kildare Miranda, Marcio L. Rodrigues, Chiara Luberto, Leonardo Nimrichter, Maurizio Del Poeta
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
Externí odkaz:
https://doaj.org/article/72914082a1a44147956ec9d5cbb88802
Autor:
Visesato Mor, Antonella Rella, Amir M. Farnoud, Ashutosh Singh, Mansa Munshi, Arielle Bryan, Shamoon Naseem, James B. Konopka, Iwao Ojima, Erika Bullesbach, Alan Ashbaugh, Michael J. Linke, Melanie Cushion, Margaret Collins, Hari Krishna Ananthula, Larry Sallans, Pankaj B. Desai, Nathan P. Wiederhold, Annette W. Fothergill, William R. Kirkpatrick, Thomas Patterson, Lai Hong Wong, Sunita Sinha, Guri Giaever, Corey Nislow, Patrick Flaherty, Xuewen Pan, Gabriele Vargas Cesar, Patricia de Melo Tavares, Susana Frases, Kildare Miranda, Marcio L. Rodrigues, Chiara Luberto, Leonardo Nimrichter, Maurizio Del Poeta
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT Recent estimates suggest that >300 million people are afflicted by serious fungal infections worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of activity. Thus, there is an urgent need for the developmen
Externí odkaz:
https://doaj.org/article/49414d7d8d034f819ce5a1e6a7715461
Autor:
Melanie T. Cushion, Justin P. Halterman, Kristy Koselny, Thomas F. Patterson, Nathan P. Wiederhold, Annette W. Fothergill, Damian J. Krysan, Chad Rappelye, Louis DiDone, Melanie Wellington, Julianne Green
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:7115-7127
Only one new class of antifungal drugs has been introduced into clinical practice in the last 30 years, and thus the identification of small molecules with novel mechanisms of action is an important goal of current anti-infective research. Here, we d
Autor:
Shawn R. Lockhart, William J. Hoekstra, Annette W. Fothergill, Thomas F. Patterson, Carol B. Bolden, Naureen Iqbal, Nathan P. Wiederhold, Robert J. Schotzinger, Nina T. Grossman, Stephen Brand, Edward P. Garvey, Elizabeth A. Ottinger
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:2528-2531
The in vitro activities of the novel fungal Cyp51 inhibitor VT-1129 were evaluated against a large panel of Cryptococcus neoformans and Cryptococcus gattii isolates. VT-1129 demonstrated potent activities against both Cryptococcus species as demonstr
Publikováno v:
Infectious Disease Clinics of North America. 30:13-35
Despite the availability of new diagnostic assays and broad-spectrum antifungal agents, invasive fungal infections remain a significant challenge to clinicians and are associated with marked morbidity and mortality. In addition, the number of etiolog
Multilaboratory Evaluation of In Vitro Antifungal Susceptibility Testing of Dermatophytes for ME1111
Autor:
Robert Rennie, Mahmoud A. Ghannoum, Luis Ostrosky-Zeichner, Daniel J. Diekema, Nathan P. Wiederhold, Vishnu Chaturvedi, Thomas J. Walsh, Nancy L. Wengenack, Annette W. Fothergill
Publikováno v:
Journal of Clinical Microbiology. 54:662-665
ME1111 is a novel small molecule antifungal agent under development for the topical treatment of onychomycosis. Standardization of the susceptibility testing method for this candidate antifungal is needed. Toward this end, 8 independent laboratories
Autor:
Amir M. Farnoud, Hari Krishna Ananthula, Lai Hong Wong, Ashutosh Singh, Visesato Mor, Michael J. Linke, Margaret S. Collins, Susana Frases, Chiara Luberto, Gabriele Vargas Cesar, Xuewen Pan, Corey Nislow, Erika E. Büllesbach, William R. Kirkpatrick, Annette W. Fothergill, Larry Sallans, Alan Ashbaugh, Iwao Ojima, James B. Konopka, Melanie T. Cushion, Marcio L. Rodrigues, Thomas F. Patterson, Leonardo Nimrichter, Arielle M. Bryan, Maurizio Del Poeta, Shamoon Naseem, Patricia de Melo Tavares, Kildare Miranda, Antonella Rella, Sunita Sinha, Nathan P. Wiederhold, Patrick Flaherty, Pankaj B. Desai, Guri Giaever, Mansa Munshi
Publikováno v:
mBio
mBio, Vol 9, Iss 2, p e00188-18 (2018)
mBio, Vol 9, Iss 2 (2018)
mBio, Vol 9, Iss 2, p e00188-18 (2018)
mBio, Vol 9, Iss 2 (2018)
Recent estimates suggest that >300 million people are afflicted by serious fungal infections worldwide. Current antifungal drugs are static and toxic and/or have a narrow spectrum of activity. Thus, there is an urgent need for the development of new
Autor:
Thomas F. Patterson, William J. Hoekstra, Edward P. Garvey, Robert J. Schotzinger, Scott G. Filler, Ashraf S. Ibrahim, Teclegiorgis Gebremariam, Annette W. Fothergill, Nathan P. Wiederhold
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:7815-7817
We studied the efficacy of the investigational drug VT-1161 against mucormycosis. VT-1161 had more potent in vitro activity against Rhizopus arrhizus var. arrhizus than against R. arrhizus var. delemar . VT-1161 treatment demonstrated dose-dependent
Autor:
Josep Guarro, Deanna A. Sutton, Annette W. Fothergill, José F. Cano-Lira, Marcelo Sandoval-Denis, Josepa Gené, Nathan P. Wiederhold
Publikováno v:
Journal of Clinical Microbiology. 52:2112-2125
A set of 73 isolates of the emerging fungus Trichoderma isolated from human and animal clinical specimens were characterized morphologically and molecularly using a multilocus sequence analysis that included the internal transcribed spacer (ITS) regi
Autor:
Elena Orsetti, Deanna A. Sutton, E. Marchionni, Francesco Barchiesi, Rosaria Gesuita, E. Gabrielli, Annette W. Fothergill, Lucia Brescini, Pamela Castelli, Silvia Staffolani
Publikováno v:
Clinical Microbiology and Infection. 20:559-565
Aspergillus osteomyelitis is a rare infection. We reviewed 310 individual cases reported in the literature from 1936 to 2013. The median age of patients was 43 years (range, 0–86 years), and 59% were males. Comorbidities associated with this infect