Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Annette T Byrne"'
Autor:
Monika A Jarzabek, William R Proctor, Jennifer Vogt, Rupal Desai, Patrick Dicker, Gary Cain, Rajiv Raja, Jens Brodbeck, Dale Stevens, Eric P van der Stok, John W M Martens, Cornelis Verhoef, Priti S Hegde, Annette T Byrne, Jacqueline M Tarrant
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198099 (2018)
Drug-related sinusoidal dilatation (SD) is a common form of hepatotoxicity associated with oxaliplatin-based chemotherapy used prior to resection of colorectal liver metastases (CRLM). Recently, hepatic SD has also been associated with anti-delta lik
Externí odkaz:
https://doaj.org/article/fe0051c7ad654064b4d0da667c7b0515
Autor:
Alice C O'Farrell, Rhys Evans, Johanna M U Silvola, Ian S Miller, Emer Conroy, Suzanne Hector, Maurice Cary, David W Murray, Monika A Jarzabek, Ashwini Maratha, Marina Alamanou, Girish Mallya Udupi, Liam Shiels, Celine Pallaud, Antti Saraste, Heidi Liljenbäck, Matti Jauhiainen, Vesa Oikonen, Axel Ducret, Paul Cutler, Fionnuala M McAuliffe, Jacques A Rousseau, Roger Lecomte, Suzanne Gascon, Zoltan Arany, Bonnie Ky, Thomas Force, Juhani Knuuti, William M Gallagher, Anne Roivainen, Annette T Byrne
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169964 (2017)
Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to develop rational mechanism driven approaches for the early detection of cardiac dysfunction
Externí odkaz:
https://doaj.org/article/a50b8f08c3d74280a693b5b4bb9f1718
Autor:
Tom Venken, Ian S. Miller, Ingrid Arijs, Valentina Thomas, Ana Barat, Johannes Betge, Tianzuo Zhan, Timo Gaiser, Matthias P. Ebert, Alice C. O’Farrell, Jochen Prehn, Rut Klinger, Darran P. O’Connor, Brian Moulton, Verena Murphy, Garazi Serna, Paolo G. Nuciforo, Ray McDermott, Brian Bird, Gregory Leonard, Liam Grogan, Anne Horgan, Nadine Schulte, Markus Moehler, Diether Lambrechts, Annette T. Byrne
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract To predict outcome to combination bevacizumab (BVZ) therapy, we employed cell-free DNA (cfDNA) to determine chromosomal instability (CIN), nucleosome footprints (NF) and methylation profiles in metastatic colorectal cancer (mCRC) patients. L
Externí odkaz:
https://doaj.org/article/7492becf8fc3468584cbff1ca25b4e7f
Autor:
Kathryn H. Brown, Brianna N. Kerr, Mihaela Pettigrew, Kate Connor, Ian S. Miller, Liam Shiels, Colum Connolly, Conor McGarry, Annette T. Byrne, Karl T. Butterworth
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 31, Iss , Pp 100615- (2024)
Background and purpose: Radiomics analysis extracts quantitative data (features) from medical images. These features could potentially reflect biological characteristics and act as imaging biomarkers within precision medicine. However, there is a lac
Externí odkaz:
https://doaj.org/article/2be7e99c676a450782c0e39431b9e40d
Autor:
Kate Connor, Emer Conroy, Kieron White, Liam P. Shiels, Simon Keek, Abdalla Ibrahim, William M. Gallagher, Kieron J. Sweeney, James Clerkin, David O’Brien, Jane B. Cryan, Philip J. O’Halloran, Josephine Heffernan, Francesca Brett, Philippe Lambin, Henry C. Woodruff, Annette T. Byrne
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Here, we establish a CT-radiomics based method for application in invasive, orthotopic rodent brain tumour models. Twenty four NOD/SCID mice were implanted with U87R-Luc2 GBM cells and longitudinally imaged via contrast enhanced (CE-CT) imag
Externí odkaz:
https://doaj.org/article/f5502ff7e06945ad8173541c1ee43f95
Autor:
Cathal Caulfield, Dan Wu, Ian S. Miller, Annette T. Byrne, Pól Mac Aonghusa, Sergiy Zhuk, Lorenzo Cinelli, Elisa Bannone, Jacques Marescaux, Sylvain Gioux, Michele Diana, Taryn L. March, Alexander L. Vahrmeijer, Ronan Cahill, Donal F. O’Shea
Publikováno v:
Molecules, Vol 28, Iss 5, p 2167 (2023)
A series of mono- and bis-polyethylene glycol (PEG)-substituted BF2-azadipyrromethene fluorophores have been synthesized with emissions in the near-infrared region (700–800 nm) for the purpose of fluorescence guided intraoperative imaging; chiefly
Externí odkaz:
https://doaj.org/article/352e9d5813c64b87873c8c85f2c5033f
Autor:
Giuseppe Gullo, Alex J. Eustace, Alexandra Canonici, Denis M. Collins, Michael J. Kennedy, Liam Grogan, Oscar Breathhnach, John McCaffrey, Maccon Keane, Michael J. Martin, Rajnish Gupta, Gregory Leonard, Miriam O’Connor, Paula M. Calvert, Paul Donnellan, Janice Walshe, Enda McDermott, Kathleen Scott, Andres Hernando, Imelda Parker, David W. Murray, Alice C. O’Farrell, Ashwini Maratha, Patrick Dicker, Mairin Rafferty, Verena Murphy, Norma O’Donovan, William M. Gallagher, Bonnie Ky, Dimitrios Tryfonopoulos, Brian Moulton, Annette T. Byrne, John Crown
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Combining bevacizumab and chemotherapy produced superior response rates compared with chemotherapy alone in metastatic breast cancer. As bevacizumab may cause hypertension (HTN) and increase the risk of cardiac failure, we performed a pil
Externí odkaz:
https://doaj.org/article/dd373e9d21d44deea251f3cc0cedb80b
Autor:
Archita Biswas, Manuela Salvucci, Kate Connor, Heiko Düssmann, Steven Carberry, Michael Fichtner, Ellen King, Brona Murphy, A.C O’Farrell, Jane Cryan, Alan Beausang, Josephine Heffernan, Mattia Cremona, Bryan T. Hennessy, James Clerkin, Kieron J. Sweeney, Steve MacNally, F Brett, P O’Halloran, Orna Bacon, Simon Furney, Maite Verreault, Emie Quissac, Franck Bielle, Mohammed H Ahmed, Ahmed Idbaih, Sieger Leenstra, Ioannis Ntafoulis, Federica Fabro, Martine Lamfers, Anna Golebiewska, Frank Hertel, Simone P Niclou, Romain Tching Chi Yen, Andreas Kremer, Gonca Dilcan, Francesca Lodi, Ingrid Arijs, Diether Lambrechts, Manasa Kalya P, Alexander Kel, Annette T Byrne, Jochen H.M Prehn
Publikováno v:
Journal of Neuro-Oncology.
Background Glioblastoma (GBM) is an aggressive brain cancer that typically results in death in the first 15 months after diagnosis. There have been limited advances in finding new treatments for GBM. In this study, we investigated molecular differenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbe974f6f42cb2b07d76383d9af2fbe
https://doi.org/10.1007/s11060-023-04341-3
https://doi.org/10.1007/s11060-023-04341-3
Autor:
Alberto Villanueva, Livio Trusolino, Joan Seoane, Sergio Roman-Roman, Gunhild Mari Mælandsmo, Jos Jonkers, Steven de Jong, Robert B. Clarke, Carlos Caldas, Annette T. Byrne, Eva Budinská, Andrew V. Biankin, Frederic Amant, Manuel Hidalgo
Supplementary Table 1: Mouse Strains Used to Develop PDX Models. Supplementary Table 2: Collection of PDX Models Available by the EuroPDX Consortium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847d6135316da652129891828469606b
https://doi.org/10.1158/2159-8290.22532248
https://doi.org/10.1158/2159-8290.22532248
Autor:
Alberto Villanueva, Livio Trusolino, Joan Seoane, Sergio Roman-Roman, Gunhild Mari Mælandsmo, Jos Jonkers, Steven de Jong, Robert B. Clarke, Carlos Caldas, Annette T. Byrne, Eva Budinská, Andrew V. Biankin, Frederic Amant, Manuel Hidalgo
Genomics Mimicry for Personalized Cancer Treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb381bd630b21993d016560ef562836f
https://doi.org/10.1158/2159-8290.22532254
https://doi.org/10.1158/2159-8290.22532254