Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Annette Steward"'
Autor:
Jürgen Jänes, Yan Dong, Michael Schoof, Jacques Serizay, Alex Appert, Chiara Cerrato, Carson Woodbury, Ron Chen, Carolina Gemma, Ni Huang, Djem Kissiov, Przemyslaw Stempor, Annette Steward, Eva Zeiser, Sascha Sauer, Julie Ahringer
Publikováno v:
eLife, Vol 7 (2018)
An essential step for understanding the transcriptional circuits that control development and physiology is the global identification and characterization of regulatory elements. Here, we present the first map of regulatory elements across the develo
Externí odkaz:
https://doaj.org/article/582ead22eb294d38bc8ceda60f6ee401
Publikováno v:
J Biol Chem
The Journal of biological chemistry, vol 295, iss 33
The Journal of Biological Chemistry
The Journal of biological chemistry, vol 295, iss 33
The Journal of Biological Chemistry
The health of a cell depends on accurate translation and proper protein folding, whereas misfolding can lead to aggregation and disease. The first opportunity for a protein to fold occurs during translation, when the ribosome and surrounding environm
Autor:
Jeffrey R. Kuhn, Ariel M. Pani, Bob Goldstein, Annette Steward, Julie Ahringer, Christopher D. Higgins, Jennifer K. Heppert, Daniel J. Dickinson
Publikováno v:
Molecular Biology of the Cell
Fluorescent protein tags are the primary tool for labeling gene products and analyzing their dynamics using live-cell imaging. A quantitative comparison is made of fluorescent protein brightness and photostability in an in vivo animal model system, a
Autor:
Sascha Sauer, Ron A.-J. Chen, Carson Woodbury, Djem Kissiov, Jürgen Jänes, Michael Schoof, Annette Steward, Julie Ahringer, Chiara Cerrato, Yan Dong, Eva Zeiser, Ni Huang, Jacques Serizay, Alex Appert, Przemyslaw Stempor, Carolina Gemma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9342114ddfca4f98b06c66ab9ae727ed
https://doi.org/10.7554/elife.37344.039
https://doi.org/10.7554/elife.37344.039
Autor:
Przemyslaw Stempor, Jacques Serizay, Jürgen Jänes, Carolina Gemma, Ron A.-J. Chen, Julie Ahringer, Michael Schoof, Annette Steward, Ni Huang, Carson Woodbury, Alex Appert, Chiara Cerrato, Djem Kissiov, Yan Dong, Eva Zeiser, Sascha Sauer
An essential step for understanding the transcriptional circuits that control development and physiology is the global identification and characterization of regulatory elements. Here we present the first map of regulatory elements across the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abec52b456fb496b1e9c5a34ef6f755a
Autor:
Jeffrey J. Hollins, Renuka Kudva, Patrick J. Shilling, Robert B. Best, Pengfei Tian, Gunnar von Heijne, Jane Clarke, Adrian A. Nickson, Ting Su, Annette Steward, Roland Beckmann
Proteins that fold cotranslationally may do so in a restricted configurational space, due to the volume occupied by the ribosome. How does this environment, coupled with the close proximity of the ribosome, affect the folding pathway of a protein? Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e708943f8d9aaad72c5e0d3b2678d59
https://doi.org/10.1101/253013
https://doi.org/10.1101/253013
Autor:
Ariel M. Pani, Jennifer K. Heppert, Christopher D. Higgins, Julie Ahringer, Daniel J. Dickinson, Annette Steward, Jeffrey R. Kuhn, Bob Goldstein
Fluorescent protein tags are fundamental tools used to visualize gene products and analyze their dynamicsin vivo. Recent advances in genome editing have enabled precise insertion of fluorescent protein tags into the genomes of diverse organisms. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cdef34a5ebe82cd9382bbc3715f27c
Publikováno v:
Biophysical Journal. 114:593a
Autor:
Annette Steward, Alessandro Borgia, Fleur A. C. Bone, Jane Clarke, Nuala R. Tumelty, Lee Gyan Kwa, Zheng Ming Chan, Beth G. Wensley, Sarah Batey
Publikováno v:
Nature. 463:685-688
Energy landscape theory is a powerful tool for understanding the structure and dynamics of complex molecular systems, in particular biological macromolecules1. The primary sequence of a protein defines its free energy landscape, and thus determines t
Autor:
Yasushi Kondo, Jane Clarke, Tina Perica, Xiuwei Zhang, Annette Steward, Sarah A. Teichmann, Sandhya Premnath Tiwari, Katherine R. Kemplen, Nathalie Reuter, Stephen H. McLaughlin
Publikováno v:
Science
Introduction Evolution and design of protein complexes are frequently viewed through the lens of amino acid mutations at protein interfaces, but we showed previously that residues distant from interfaces are also commonly involved in the evolution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7797c99d360d60eb5e5090d08e429b7c
https://www.repository.cam.ac.uk/handle/1810/246409
https://www.repository.cam.ac.uk/handle/1810/246409