Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Annette Rempel"'
Autor:
Saroj P. Mathupala, Peter L. Pedersen, Jean Francois H. Geschwind, Annette Rempel, Young Hee Ko
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1555:14-20
Despite more than 75 years of research by some of the greatest scientists in the world to conquer cancer, the clear winner is still cancer. This is reflected particularly by liver cancer that worldwide ranks fourth in terms of mortality with survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31f4d2bc9bf42da044a7e85bd0874d6
https://doi.org/10.1016/s0005-2728(02)00248-7
https://doi.org/10.1016/s0005-2728(02)00248-7
Publikováno v:
Journal of Biological Chemistry. 276:43407-43412
One of the most common signatures of highly malignant tumors is their capacity to metabolize more glucose to lactic acid than their tissues of origin. Hepatomas exhibiting this phenotype are dependent on the high expression of type II hexokinase, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30123d0d723793fa512b8f8a7df8c644
https://doi.org/10.1074/jbc.m108181200
https://doi.org/10.1074/jbc.m108181200
Autor:
Annette Rempel, Reinhard Buettner, Judith M. Müller, Christian Holubarsch, Roland Schüle, Tobias Breyer, Ulrike Isele, Armin Pscherer, Eric Metzger, Markus Moser
Publikováno v:
The EMBO Journal. 19:359-369
The control of target gene expression by nuclear receptors requires the recruitment of multiple cofactors. However, the exact mechanisms by which nuclear receptor-cofactor interactions result in tissue-specific gene regulation are unclear. Here we ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1c1b840a269ddb38ee26d263af21d8
https://doi.org/10.1093/emboj/19.3.359
https://doi.org/10.1093/emboj/19.3.359
Autor:
Hendrik Graefe, Carola Mala, Barbara Wollenberg, Annette Rempel, Markus Bürgle, Carsten Brocks, Natalie Thäns, Nicole Rotter, Jens E. Meyer, Stephan Lang
Publikováno v:
Breast care (Basel, Switzerland). 3(s2)
Tumour invasion and metastasis depend on the capacity of tumour cells to coordinate various biological processes such as detachment of cells from their original localisation, cancer cell migration, invasion of cancer cells into surrounding tissue, ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a482a79afdb7ad2fde41c7a1598ce7
https://pubmed.ncbi.nlm.nih.gov/20824010
https://pubmed.ncbi.nlm.nih.gov/20824010
Autor:
Manfred Schmitt, Jens E. Meyer, Stefan Paepke, Nicole Rotter, Nadia Harbeck, Christoph Thomssen, Carsten Brocks, Natalie Thäns, Rudolf Napieralski, Jonathan W. Uhr, Daniela Paepke, Anneke Geurts-Moespot, Lori J. Goldstein, Fritz Jänicke, Barbara Wollenberg, Annette Rempel, Janna Krol, C. Mala, Hendrik Graefe, Gunter von Minckwitz, Ute Reuning, Markus Bürgle, Viktor Magdolen, Mathias Uhlig, Apostolos Gkazepis, Karin Mengele, Fred C.G.J. Sweep, Martina Vetter, Stephan Lang, Paul Bevan
Publikováno v:
Breast Care. 3:III-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d27038d15996cc8a753d4f45e0190aa
https://doi.org/10.1159/000174025
https://doi.org/10.1159/000174025
Publikováno v:
FEBS letters. 385(3)
The increased glucose consumption of many tumor cells depends to a large extent on the overexpression of hexokinase Type II. In a previous study we isolated and sequenced the hepatoma Type II hexokinase promoter and showed that it is activated by glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3848ef78d83df02cb351090b67434b
https://pubmed.ncbi.nlm.nih.gov/8647258
https://pubmed.ncbi.nlm.nih.gov/8647258
Publikováno v:
Biochimica et biophysica acta. 1219(3)
The activity, intracellular distribution and mRNA expression of hexokinase isoenzymes were studied in normal rat liver, and in epithelial liver cells at different stages of neoplastic transformation, including non-tumorigenic and tumorigenic cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd5e280d1cd1b3160f0946050da092d
https://pubmed.ncbi.nlm.nih.gov/7948023
https://pubmed.ncbi.nlm.nih.gov/7948023