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pro vyhledávání: '"Annette Pressley"'
Autor:
Stephen A. Liebhaber, Ingrid Weiss, Annette Pressley, Mary B. Coleman, Junius G. Adams, T Sanguansermsri, Martin H. Steinberg, F E Cash
Publikováno v:
Blood. 76:2630-2636
Hemoglobin (Hb) Suan-Dok (alpha 109Arg) is a rare alpha-globin structural mutation that is linked to an alpha-thalassemia (alpha-thal) determinant. When inherited in trans to an alpha-thal-1 mutation (-), it results in Hb H disease associated with lo
Publikováno v:
British journal of haematology. 47(1)
We examined globin chain synthesis in erythroid bursts (BFU-E) of patients with heterozygous alpha or beta thalassaemia. BFU-E were cloned from circulating mononuclear cells, labelled with [3H]leucine and globin chains purified by gel filtration and
Autor:
M. B. Coleman, Annette Pressley, Hernan E. Grenett, Martin H. Steinberg, Fred A. Garver, Junius G. Adams
Publikováno v:
American journal of hematology. 10(1)
Colonies derived from erythroid burst-forming units (BFU-E) synthesize fetal hemoglobin (HbF) in amounts that far exceed in vivo levels. There is some evidence that HbF synthesis is controlled at the level of a primitive erythroid precursor cell. Dex