Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Annette Neubüser"'
Autor:
Jakob Siebert, Michaela Schneider, Daniela Reuter‐Schmitt, Julia Würtemberger, Annette Neubüser, Wolfgang Driever, Simone Hettmer, Friedrich G. Kapp
Publikováno v:
Pediatric Blood & Cancer. 70
Rhabdomyosarcomas (RMS) are the most common pediatric soft tissue sarcomas. High-risk and metastatic disease continues to be associated with very poor prognosis. RMS model systems that faithfully recapitulate the human disease and provide rapid, cost
Autor:
Anna Ferrer-Vaquer, Rebekka Götz, David Herrmann, Annette Neubüser, Alisa Fuchs, Shuofei Cheng, Mariko Kawai, Kiyoshi Ohura, Katrin Driller
Publikováno v:
Medical Molecular Morphology. 52:156-163
Most facial bones, including frontal bones, are derived from neural crest cells through intramembranous ossification. Fibroblast growth factor receptor 1 (Fgfr1) plays a pivotal role in craniofacial bone development, and loss of Fgfr1 leads to cleft
Publikováno v:
Developmental Dynamics. 240:1578-1585
Ephrins and their tyrosine kinase receptors (Ephs) are a highly conserved family of signaling proteins with various functions during embryonic development. Among others, Eph/ephrin signaling is involved in regulating axon guidance, cell migration, an
Autor:
Annette Neubüser, Heiko Peters, Mitsushiro Nakatomi, Alisa Fuchs, Andrea Inthal, David Herrmann, Shuofei Cheng
Publikováno v:
Developmental Dynamics. 239:2860-2874
Mutations in the gene encoding the T-box transcription factor TBX22 cause X-linked cleft palate and ankyloglossia in humans. Here we show that Tbx22 expression during facial and palatal development is regulated by FGF and BMP signaling. Our results d
Autor:
Annette Neubüser, David Herrmann, Nicole Firnberg, Andreas Leibbrandt, Christian Lahsnig, Anna Ferrer-Vaquer
Publikováno v:
Developmental Dynamics. 239:680-687
Anthrax Toxin Receptor 1 (ANTXR1; also known as Tumor Endothelial Marker 8, TEM8) is one of several genes that was recently found to be up-regulated in tumor-associated endothelial cells. In vitro, the protein can link extracellular matrix components
Publikováno v:
Gene Expression Patterns. 7:808-816
Apoptosis signal-regulating kinase 1 (ASK1) is an important regulator of stress-induced cell death. ASK1 is activated by oxidative stress, TNF and endoplasmatic reticulum stress and activates the JNK- and p38-dependent intracellular death pathways. A
Publikováno v:
Developmental Biology. 294(1):11-23
The development of digestive organs in vertebrates involves active epithelial–mesenchymal interactions. In the chicken proventriculus (glandular stomach), the morphogenesis and cytodifferentiation of the epithelium are controlled by the inductive s
Autor:
Markus Mandler, Annette Neubüser
Publikováno v:
Development. 131:3333-3343
Morphogenesis of hairs and feathers is initiated by an as yet unknown dermal signal that induces placode formation in the overlying ectoderm. To determine whether FGF signals are required for this process we over-expressed soluble versions of FGFR1 o
Autor:
Marta Carapuço, Benoît Kanzler, Andreas Leibbrandt, Nicoletta Bobola, Sabine Ohnemus, Jacques Drouin, Moisés Mallo, Annette Neubüser
Publikováno v:
Development. 130:3403-3414
Hox genes are known key regulators of embryonic segmental identity, but little is known about the mechanisms of their action. To address this issue,we have analyzed how Hoxa2 specifies segmental identity in the second branchial arch. Using a subtract
Publikováno v:
Trends in Biochemical Sciences. 28:226-229
We have identified a conserved sequence segment in transmembrane receptors (including SEFs, IL17Rs) and soluble factors (including CIKS/ACT1) in eukaryotes and bacteria - the SEFIR domain. This sequence domain is part of the new STIR domain superfami