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pro vyhledávání: '"Annette Miles-Williams"'
Autor:
Diane M. Coe, Simon J. F. Macdonald, Davina Humphreys, Philip Alan Skone, Haydn Terence Jones, George Hardy, Iain M. McLay, Annette Miles-Williams, David House, Matilde Caivano, Iain Uings, Keith Biggadike, Margaret Clackers, Vicki Weller
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:4846-4850
Starting from a non-steroidal glucocorticoid agonist aryl pyrazole derivative, the NFκB agonist activity was optimised in an iterative process from pIC50 7.5 (for 7), to pIC50 10.1 (for 38E1). An explanation for the SAR observed based is presented a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb7fb2263d54a89f13a1a813d392687
https://doi.org/10.1016/j.bmcl.2009.06.020
https://doi.org/10.1016/j.bmcl.2009.06.020
