Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Annette M. Stemerding"'
Autor:
Lenny Hogerwerf, Pim M. Post, Ben Bom, Wim van der Hoek, Jan van de Kassteele, Annette M. Stemerding, Wilco de Vries, Danny Houthuijs
Publikováno v:
International Journal of Hygiene and Environmental Health, 245:114022, 1-9. Urban und Fischer Verlag Jena
ObjectivesIn the Netherlands, during the first phase of the COVID-19 epidemic, the hotspot of COVID-19 overlapped with the country’s main livestock area, while in subsequent phases this distinct spatial pattern disappeared. Previous studies show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0aa205b23a51dcf58fe221492d20ee
https://research.utwente.nl/en/publications/b8c62b31-bdf7-4231-aade-9a2416bb9e30
https://research.utwente.nl/en/publications/b8c62b31-bdf7-4231-aade-9a2416bb9e30
Publikováno v:
Immunological Reviews. 268:253-268
The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in various tissues, providing newborns with humoral immunity, and for prolonging the half-life of IgG. Recent findings implicate the involvement of FcRn in a far wider ran
Autor:
Annette M. Stemerding, Peter van Ulsen, Jan G. J. van de Winkel, Mogens Kilian, Peter van der Ley, Natasja Overbeeke, Germie P. J. M. van den Dobbelsteen, Gestur Vidarsson
Publikováno v:
Infection and immunity, 73(10), 6721-6726. American Society for Microbiology
Vidarsson, G, Overbeeke, N, Stemerding, AM, van den Dobbelsteen, G, van Ulsen, P, van der Ley, P, Kilian, M & van de Winkel, JGJ 2005, ' Working mechanism of immunoglobulin A1 (IgA1) protease: cleavage of IgA1 antibody to Neisseria meningitidis PorA requires de novo synthesis of IgA1 Protease ', Infection and Immunity, vol. 73, pp. 6721-26 .
Vidarsson, G, Overbeeke, N, Stemerding, AM, van den Dobbelsteen, G, van Ulsen, P, van der Ley, P, Kilian, M & van de Winkel, JGJ 2005, ' Working mechanism of immunoglobulin A1 (IgA1) protease: cleavage of IgA1 antibody to Neisseria meningitidis PorA requires de novo synthesis of IgA1 Protease ', Infection and Immunity, vol. 73, pp. 6721-26 .
Neisseria meningitidis secretes a protease that specifically cleaves the hinge region of immunoglobulin A1 (IgA1), releasing the effector (Fc) domain of IgA1 from the antigen binding (Fab) determinants. Theoretically, the remaining Fab fragments can
Autor:
Peter Boross, Jeanette H. W. Leusen, Annemarie Y. L. Weersink, Jörg Köhl, Jos A. G. van Strijp, Jan G. J. van de Winkel, Maaike Nederend, Annette M. Stemerding, Manoj K. Pandey, Annemarie Kuipers, Gestur Vidarsson, Kok P. M. van Kessel
Publikováno v:
Journal of immunology (Baltimore, Md., 191(1), 353-362. American Association of Immunologists
To evade opsonophagocytosis, Staphylococcus aureus secretes various immunomodulatory molecules that interfere with effective opsonization by complement and/or IgG. Immune-evasion molecules targeting the phagocyte receptors for these opsonins have not
Publikováno v:
van Prehn, J, Stemerding, A M, Van Saene, H K F & Spronk, P E 2014, ' Oral vancomycin might be useful to suppress enteral VRE load: a conceptual experiment ', Intensive Care Medicine, vol. 40, no. 8, pp. 1171-1172 . https://doi.org/10.1007/s00134-014-3365-x
Intensive Care Medicine, 40(8), 1171-1172. Springer Verlag
Intensive Care Medicine, 40(8), 1171-1172. Springer Verlag
Autor:
Suzanne E. Spliethoff, Gestur Vidarsson, Jan G. J. van de Winkel, Hans Janssen, Masja de Haas, Nigel M. Stapleton, Frank Rebers, Annette M. Stemerding
Publikováno v:
Blood, 108(10), 3573-3579. American Society of Hematology
Here, we report that the MHC class I-related neonatal Fc receptor (FcRn) is expressed within azurophilic and specific granules of neutrophils and relocates to phagolysosomes on phagocytosis of IgG-opsonized bacteria. We found FcRn to enhance phagocyt
Autor:
Vanessa Walraven, J. Sjef Verbeek, Jan G. J. van de Winkel, Elisabeth A. M. Sanders, Evert van Garderen, Eirikur Saeland, Moon H. Nahm, Annette M. Stemerding, Gestur Vidarsson, Henriette Vile-Weekhout, Jeanette H. W. Leusen, Wietse Kuis, Ger T. Rijkers
Publikováno v:
Journal of immunology (Baltimore, Md., 170(12), 6158-6164. American Association of Immunologists
Streptococcus pneumoniae is an important cause of morbitity and mortality worldwide. Capsule-specific IgG1 and IgG2 Abs are induced upon vaccination with polysaccharide-based vaccines that mediate host protection. We compared the protective capacity
Autor:
Masja de Haas, Yixian Zhao, Nigel M. Stapleton, Stefania P. Bjarnarson, Ruurd C. Verheul, Inger Sandlie, Ingileif Jonsdottir, Annette M. Stemerding, Jan Terje Andersen, Jorrit Gerritsen, Gestur Vidarsson, C. Ellen van der Schoot, Marion Kleijer
Publikováno v:
Nature Communications
Nature communications, 2. Nature Publishing Group
Nature communications, 2. Nature Publishing Group
Human IgG3 displays the strongest effector functions of all IgG subclasses but has a short half-life for unresolved reasons. Here we show that IgG3 binds to IgG-salvage receptor (FcRn), but that FcRn-mediated transport and rescue of IgG3 is inhibited