Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Annette M. Shipp"'
Autor:
Joseph F. Borzelleca, Robert R. Maronpot, Annette M. Shipp, James A. Swenberg, Joseph V. Rodricks
Publikováno v:
Critical Reviews in Toxicology. 40:422-484
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The tolerability and safety of triclosan has been evaluated in human volunteers with little indication of
Autor:
Annette M. Shipp, Martha M. Moore, Robert H. Heflich, Ralph L. Kodell, Bruce C. Allen, Lynne T. Haber
Publikováno v:
Regulatory Toxicology and Pharmacology. 51:151-161
Under the new U.S. Environmental Protection Agency (EPA) Cancer Risk Assessment Guidelines [U.S. EPA, 2005. Guidelines for Carcinogen Risk Assessment. EPA/630/P-03/001B, March 2005], the quantitative model chosen for cancer risk assessment is based o
Autor:
Harvey J. Clewell, H Bartow, J Bounds, N Macdonald, Annette M. Shipp, C. Van Landingham, Tracy B. McDonald, Greg Lawrence, Bruce C. Allen, R Gentry
Publikováno v:
Critical Reviews in Toxicology. 36:481-608
Acrylamide (ACR) is used in the manufacture of polyacrylamides and has recently been shown to form when foods, typically containing certain nutrients, are cooked at normal cooking temperatures (e.g., frying, grilling or baking). The toxicity of ACR h
Publikováno v:
Regulatory Toxicology and Pharmacology. 41:6-27
Methods for dose-response modeling of in vivo genotoxicity data are introduced and applied to a case study of acrylamide. Genetic toxicity results are typically summarized as being either positive or negative, with no further consideration of the dos
Autor:
Greg Lawrence, Bruce J. Tuovila, Annette M. Shipp, Edward J. Zillioux, Cynthia Van Landingham, Christopher M. Teaf
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 10:665-682
Epidemiological studies of workers in the nickel industry, animal exposure studies, and reports on the potential mechanisms of nickel-induced toxicity and carcinogenicity indicate that only crystalline sulfidic nickel compounds have been clearly esta
Autor:
Tammie R. Covington, Annette M. Shipp, Sabine Mann, P. Robinan Gentry, Janice W. Yager, Harvey J. Clewell
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 67:43-71
A remarkable feature of the carcinogenicity of inorganic arsenic is that while human exposures to high concentrations of inorganic arsenic in drinking water are associated with increases in skin, lung, and bladder cancer, inorganic arsenic has not ty
Autor:
David J. George, Annette M. Shipp
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 21:31-50
Autor:
Greg Lawrence, Tammie R. Covington, Justin G. Teeguarden, Annette M. Shipp, Ramesh Sarangapani, Tracy McDonald, Robinan Gentry, Harvey J. Clewell
Publikováno v:
Critical Reviews in Toxicology. 32:329-389
In standard risk assessment methods for carcinogenic or noncarcinogenic chemicals, quantitative methods for evaluating interindividual variability are not explicitly considered. These differences are currently considered by the use of statistical con
Publikováno v:
Risk Analysis. 21:641-656
The T25 single-point estimate method of evaluating the carcinogenic potency of a chemical, which is currently used by the European Union (EU) and is denoted the EU approach, is based on the selection of a single dose in a chronic bioassay with an inc
Autor:
Tammie R. Covington, Harvey J. Clewell, P. Robinan Gentry, Cynthia B. Van Landingham, Kirk Gribben, Annette M. Shipp, Kenny S. Crump, Greg Lawrence
Publikováno v:
Toxicology and Industrial Health. 16:335-438
Environmental risk-management decisions in the U.S. involving potential exposures to methylmercury currently use a reference dose (RfD) developed by the U.S. Environmental Protection Agency (USEPA). This RfD is based on retrospective studies of an ac