Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Annette M Lim"'
Autor:
Dirk Schadendorf, Thomas K Eigentler, Israel Lowy, Apostolos Papachristos, Samantha Bowyer, Friedegund Meier, Brigitte Dreno, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Brett G M Hughes, Axel Hauschild, Brian Stein, Emmanuel Okoye, Jocelyn Booth, Matthew G Fury, Alexander Guminski, Sophie Dalac, Frank Seebach, Marie Beylot-Barry, Suk-Young Yoo, Nicole Basset-Séguin, Sabiha Trabelsi Messai, Victoria Casado Echarren, Anne J Paccaly, Jenny-Hoa Nguyen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Cemiplimab (Libtayo®), a human monoclonal immunoglobulin G4 antibody to the programmed cell death-1 receptor, is approved for the treatment of patients with advanced cutaneous squamous cell carcinoma (CSCC), who are not candidates for cur
Externí odkaz:
https://doaj.org/article/85c0508e98f2481db714933c819add16
Autor:
Dirk Schadendorf, Chieh-I Chen, Zhen Chen, Israel Lowy, Elizabeth Stankevich, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Brett G M Hughes, Anne Lynn S Chang, Emmanuel Okoye, Jocelyn Booth, Siyu Li, Matthew G Fury, Alexander Guminski, Medha Sasane, Alesha A Thai, Suk-Young Yoo, Vera Mastey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background To provide pooled longer term data from three groups of a phase 2 study of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (CSCC), and to determine duration of response (DOR) and impact on quality of life (QoL).Metho
Externí odkaz:
https://doaj.org/article/909409bad2c44f6ca8b681b154002319
Autor:
Dirk Schadendorf, Ralf Gutzmer, Thomas Eigentler, Israel Lowy, Vladimir Jankovic, Elizabeth Stankevich, Anna C Pavlick, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Nikhil I Khushalani, Brett G M Hughes, Lara A Dunn, Leonel Hernandez-Aya, Anne Lynn S Chang, Badri Modi, Axel Hauschild, Claas Ulrich, Brian Stein, Jessica L Geiger, Murad Alam, Emmanuel Okoye, Melissa Mathias, Jocelyn Booth, Siyu Li, Matthew G Fury, Alexander Guminski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Cemiplimab, a high-affinity, potent human immunoglobulin G4 monoclonal antibody to programmed cell death-1 demonstrated antitumor activity in a Phase 1 advanced cutaneous squamous cell carcinoma (CSCC) expansion cohort (NCT02383212) and th
Externí odkaz:
https://doaj.org/article/a6c7cd3cc4a44c238d9eeebc62a5df0f
Autor:
Katie Meehan, Connull Leslie, Michaela Lucas, Angela Jacques, Bob Mirzai, James Lim, Max Bulsara, Yasir Khan, Nicholas C. Wong, Benjamin Solomon, Chady Sader, Peter Friedland, Gisela Mir Arnau, Timothy Semple, Annette M. Lim
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4791-4807 (2020)
Abstract We investigated whether a unique immune response was instigated with the development of oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement, with/without recurrent metastatic disease, or within tumor involved nodes.
Externí odkaz:
https://doaj.org/article/c08ee623e4694fc1995cafcc8f96480a
Publikováno v:
American Journal of Clinical Dermatology. 24:25-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5aae1d6ad4f7e159647b9f6ec690307
https://doi.org/10.1007/s40257-022-00742-8
https://doi.org/10.1007/s40257-022-00742-8
Autor:
Neil D. Gross, David M. Miller, Nikhil I. Khushalani, Vasu Divi, Emily S. Ruiz, Evan J. Lipson, Friedegund Meier, Yungpo B. Su, Paul L. Swiecicki, Jennifer Atlas, Jessica L. Geiger, Axel Hauschild, Jennifer H. Choe, Brett G.M. Hughes, Dirk Schadendorf, Vishal A. Patel, Jade Homsi, Janis M. Taube, Annette M. Lim, Renata Ferrarotto, Howard L. Kaufman, Frank Seebach, Israel Lowy, Suk-Young Yoo, Melissa Mathias, Keilah Fenech, Hyunsil Han, Matthew G. Fury, Danny Rischin
Publikováno v:
N Engl J Med
BACKGROUND: In a pilot study involving patients with cutaneous squamous-cell carcinoma, a high percentage of patients had a pathological complete response with the use of two doses of neoadjuvant cemiplimab before surgery. Data from a phase 2 study a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d3e2fdf20eb85b8e038cbdb04bb6d9
https://doi.org/10.1056/nejmoa2209813
https://doi.org/10.1056/nejmoa2209813
Autor:
Piyush Grover, Colin Tang, Satvinder S. Dhaliwal, Elizabeth Kernutt, Joshua Dass, Joanna Dewar, Rohen White, Annette M. Lim
Purpose Mucositis remains a challenging complication of radiotherapy or chemoradiotherapy (CRT) for head and neck cancer (HNC) patients. There is limited data on the safety or effectiveness of cocaine mouthwash (CMW) to treat mucositis. Methods This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b081ec015e5ef5ed407dcdb16ee6a82e
https://doi.org/10.21203/rs.3.rs-2267766/v1
https://doi.org/10.21203/rs.3.rs-2267766/v1
Autor:
Nicholas C. Wong, Michael Clark, Annette M. Lim, Michael Millward, Bella Nguyen, Katie Meehan, Bob Mirzai, Connull Leslie, Stephen Q. Wong, Timothy Semple
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared copy number alteration (CNA) profiles gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e97f7d3c7a553907e0d9af76ff9cab
https://doaj.org/article/a36570840ea1407d81af8c168aa6556e
https://doaj.org/article/a36570840ea1407d81af8c168aa6556e
Autor:
Nicholas C. Wong, Benjamin Solomon, Max Bulsara, Peter L. Friedland, James Lim, Michaela Lucas, Bob Mirzai, Katie Meehan, Yasir Khan, Chady Sader, Gisela Mir Arnau, Connull Leslie, Angela Jacques, Annette M. Lim, Timothy Semple
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 13, Pp 4791-4807 (2020)
Cancer Medicine, Vol 9, Iss 13, Pp 4791-4807 (2020)
We investigated whether a unique immune response was instigated with the development of oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement, with/without recurrent metastatic disease, or within tumor involved nodes. One hundr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a267c5efe00344befa7cc86a4294a376
http://europepmc.org/articles/PMC7333861
http://europepmc.org/articles/PMC7333861
Autor:
Luke S. McLean, Annette M. Lim, Angela Webb, Karda Cavanagh, Alesha Thai, Matthew Magarey, Carly Fox, Stephen Kleid, Danny Rischin
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2022)
Frontiers in Oncology, Vol 11 (2022)
BackgroundCutaneous squamous cell carcinoma (CSCC) of the head and neck can require complex and disfiguring surgery in order to achieve cure, which can be morbid and negatively impact patient quality of life. The management of advanced CSCC has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f77bbb8868f4d1ab67a53f24f43efe
https://doi.org/10.3389/fonc.2021.796197
https://doi.org/10.3389/fonc.2021.796197