Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Annette M Lim"'
Autor:
Karda Cavanagh, Luke S. McLean, Annette M. Lim, Anthony Cardin, Sidney M. Levy, Danny Rischin
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Cutaneous squamous cell carcinoma (CSCC) has a propensity for perineural spread (PNS) which is associated with poorer treatment outcomes. Immunotherapy is the new standard of care treatment for advanced CSCC resulting in durable r
Externí odkaz:
https://doaj.org/article/a53d1392e6e24d3190ce18dea55dfaee
Autor:
Dirk Schadendorf, Thomas K Eigentler, Israel Lowy, Apostolos Papachristos, Samantha Bowyer, Friedegund Meier, Brigitte Dreno, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Brett G M Hughes, Axel Hauschild, Brian Stein, Emmanuel Okoye, Jocelyn Booth, Matthew G Fury, Alexander Guminski, Sophie Dalac, Frank Seebach, Marie Beylot-Barry, Suk-Young Yoo, Nicole Basset-Séguin, Sabiha Trabelsi Messai, Victoria Casado Echarren, Anne J Paccaly, Jenny-Hoa Nguyen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Cemiplimab (Libtayo®), a human monoclonal immunoglobulin G4 antibody to the programmed cell death-1 receptor, is approved for the treatment of patients with advanced cutaneous squamous cell carcinoma (CSCC), who are not candidates for cur
Externí odkaz:
https://doaj.org/article/85c0508e98f2481db714933c819add16
Autor:
Luke S. McLean, Karda Cavanagh, Rodney J. Hicks, Jason Callahan, Jing Xie, Anthony Cardin, Annette M. Lim, Danny Rischin
Publikováno v:
Cancer Imaging, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background The role of FDG-PET/CT imaging in assessing response to immunotherapy in advanced cutaneous squamous cell carcinoma (CSCC) is unknown. This study compared complete metabolic response (CMR) rates by FDG-PET and RECIST1.1 via CT or
Externí odkaz:
https://doaj.org/article/775096a9e5be429ca0c1a19c0432e1b4
Autor:
Bella Nguyen, Nicholas C. Wong, Tim Semple, Michael Clark, Stephen Q. Wong, Connull Leslie, Bob Mirzai, Michael Millward, Katie Meehan, Annette M. Lim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Low-coverage whole-genome sequencing (LC-WGS) can provide insight into oncogenic molecular changes. Serum extracellular vesicles (EV) represent a novel liquid biopsy source of tumoral DNA. This study compared copy number alteration (CNA) pro
Externí odkaz:
https://doaj.org/article/a36570840ea1407d81af8c168aa6556e
Autor:
Katie Meehan, Connull Leslie, Michaela Lucas, Angela Jacques, Bob Mirzai, James Lim, Max Bulsara, Yasir Khan, Nicholas C. Wong, Benjamin Solomon, Chady Sader, Peter Friedland, Gisela Mir Arnau, Timothy Semple, Annette M. Lim
Publikováno v:
Cancer Medicine, Vol 9, Iss 13, Pp 4791-4807 (2020)
Abstract We investigated whether a unique immune response was instigated with the development of oral tongue squamous cell carcinomas (OTSCC), with/without nodal involvement, with/without recurrent metastatic disease, or within tumor involved nodes.
Externí odkaz:
https://doaj.org/article/c08ee623e4694fc1995cafcc8f96480a
Autor:
Luke S. McLean, Annette M. Lim, Angela Webb, Karda Cavanagh, Alesha Thai, Matthew Magarey, Carly Fox, Stephen Kleid, Danny Rischin
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
BackgroundCutaneous squamous cell carcinoma (CSCC) of the head and neck can require complex and disfiguring surgery in order to achieve cure, which can be morbid and negatively impact patient quality of life. The management of advanced CSCC has been
Externí odkaz:
https://doaj.org/article/2344c3d403cb4381ba212a25d00e8220
Autor:
Dirk Schadendorf, Chieh-I Chen, Zhen Chen, Israel Lowy, Elizabeth Stankevich, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Brett G M Hughes, Anne Lynn S Chang, Emmanuel Okoye, Jocelyn Booth, Siyu Li, Matthew G Fury, Alexander Guminski, Medha Sasane, Alesha A Thai, Suk-Young Yoo, Vera Mastey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Background To provide pooled longer term data from three groups of a phase 2 study of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (CSCC), and to determine duration of response (DOR) and impact on quality of life (QoL).Metho
Externí odkaz:
https://doaj.org/article/909409bad2c44f6ca8b681b154002319
Autor:
Annette M. Lim, Karda Cavanagh, Rodney J. Hicks, Luke McLean, Michelle S. Goh, Angela Webb, Danny Rischin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Non-melanoma skin cancers are one of the most common cancers diagnosed worldwide, with the highest incidence in Australia and New Zealand. Systemic treatment of locally advanced and metastatic cutaneous squamous cell carcinomas has been revolutionize
Externí odkaz:
https://doaj.org/article/bb6e9bb3f376428e9f43116586aea575
Publikováno v:
American Journal of Clinical Dermatology. 24:25-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5aae1d6ad4f7e159647b9f6ec690307
https://doi.org/10.1007/s40257-022-00742-8
https://doi.org/10.1007/s40257-022-00742-8
Autor:
Dirk Schadendorf, Ralf Gutzmer, Thomas Eigentler, Israel Lowy, Vladimir Jankovic, Elizabeth Stankevich, Anna C Pavlick, Danny Rischin, Michael R Migden, Annette M Lim, Chrysalyne D Schmults, Nikhil I Khushalani, Brett G M Hughes, Lara A Dunn, Leonel Hernandez-Aya, Anne Lynn S Chang, Badri Modi, Axel Hauschild, Claas Ulrich, Brian Stein, Jessica L Geiger, Murad Alam, Emmanuel Okoye, Melissa Mathias, Jocelyn Booth, Siyu Li, Matthew G Fury, Alexander Guminski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Cemiplimab, a high-affinity, potent human immunoglobulin G4 monoclonal antibody to programmed cell death-1 demonstrated antitumor activity in a Phase 1 advanced cutaneous squamous cell carcinoma (CSCC) expansion cohort (NCT02383212) and th
Externí odkaz:
https://doaj.org/article/a6c7cd3cc4a44c238d9eeebc62a5df0f