Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Annette L. Parks"'
Autor:
Xia Wang, Jonathan Zirin, Ruibao Zhu, Ping Peng, Rong Tao, Shu Kondo, Dong Yan, Kuniaki Saito, Liz Perkins, Henna Ragoowansi, Jin Sun, Ethan Fenton, Ryan Colbeth, Benjamin Scott Ewen-Campen, Senait Efrem, Annette L. Parks, Limmond Ayisi, Sara VanNest, Donghui Yang-Zhou, Yuhao Qiu, Cooper Cavers, Norbert Perrimon, Aram Comjean, Jian-Quan Ni, Stephanie E. Mohr, Eric Vogt, Yanhui Hu, Jinchao Yu, Lu-Ping Liu, Da Shen, Christians Villalta, Yu Jia
Publikováno v:
Genetics
The Transgenic RNAi Project (TRiP), a Drosophila melanogaster functional genomics platform at Harvard Medical School, was initiated in 2008 to generate and distribute a genome-scale collection of RNA interference (RNAi) fly stocks. To date, it has ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a4a36bfd2feb1eb8a5e80ffe79b402
https://doi.org/10.1101/852376
https://doi.org/10.1101/852376
Autor:
Donald Hall, Richelle Sopko, Atsushi Toyoda, Kim McCall, Gregory J. Hannon, Rong Tao, Shu Kondo, Dong Yan, Stephanie E. Mohr, Xia Wang, Lizabeth A. Perkins, Kathleen Ayers, Lu Ping Liu, Jian-Quan Ni, Ian Flockhart, Benjamin Czech, Marianna Foos, Norbert Perrimon, Amy Housden, Asao Fujiyama, Colleen F. Kelley, Ralph A. Neumüller, Allison Blum, Karen L. Hibbard, Sakara Randkelv, Annette L. Parks, Christians Villalta, Lynn Cooley, Richard Binari, Yanhui Hu, Laura Holderbaum, Pema Namgyal, Amanda Cavallaro, Hye Seok Shim, Audrey Miller, Qiao Huan-Huan, Donghui Yang-Zhou, Xia Jiang, Ruth Lehmann, Ryu Ueda
Publikováno v:
Europe PubMed Central
To facilitate large-scale functional studies in Drosophila, the Drosophila Transgenic RNAi Project (TRiP) at Harvard Medical School (HMS) was established along with several goals: developing efficient vectors for RNAi that work in all tissues, genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47c5f9b00533a68448de497ce1a5eb9
https://doi.org/10.1534/genetics.115.180208
https://doi.org/10.1534/genetics.115.180208
Autor:
Hugo J. Bellen, Jill Wildonger, Keith R. Hayes, Anthony A. James, Owain R. Edwards, Austin Burt, Melissa M. Harrison, Thomas C. Kaufman, Valentino M. Gantz, Norbert Perrimon, Juergen A. Knoblich, Kathy Matthews, Kevin R. Cook, Kent G. Golic, Omar S. Akbari, Ethan Bier, Simon L. Bullock, Fillip Port, Harmit S. Malik, Scott J. Gratz, Kevin M. Esvelt, Peter Duchek, George M. Church, Kate M. O'Connor-Giles, Ryu Ueda, Steven Russell, Annette L. Parks
Publikováno v:
Science. 349:927-929
This is the author accepted manuscript. The final version is available from AAAS via http://dx.doi.org/10.1126/science.aac7932
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a519118a1706d5cba6a9b80b3af3a7bc
https://doi.org/10.1126/science.aac7932
https://doi.org/10.1126/science.aac7932
Publikováno v:
Fly. 4:88-91
The Bloomington Drosophila Stock Center (BDSC) is a primary source of Drosophila stocks for researchers all over the world. It houses over 27,000 unique fly lines and distributed over 160,000 samples of these stocks this past year. This report provid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5b73c7b9ee15e5bec423a548fc3b4e
https://doi.org/10.4161/fly.4.1.11230
https://doi.org/10.4161/fly.4.1.11230
Autor:
Eric L. Pierce, Kristen M. Pfau, Marisa C. Osswalt, Annette L. Parks, Nevine A. Shalaby, Marc A. T. Muskavitch, Eric J. Morreale
Publikováno v:
Genetics. 182:1061-1076
Notch signaling is an evolutionarily conserved pathway essential for many cell fate specification events during metazoan development. We conducted a large-scale transposon-based screen in the developing Drosophila eye to identify genes involved in No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11238e0db83c732596cbeef3bc054836
https://doi.org/10.1534/genetics.108.099986
https://doi.org/10.1534/genetics.108.099986
Autor:
Gregory D. Plowman, Casey Kopczynski, Kim Lickteig, Lori Friedman, Christopher G. Winter, Matt B. Mahoney, Kellie Whittaker, Helen Francis-Lang, Marcia Belvin, Matthew V. Lorenzi, Ferhad Ahmad, Hanife Esengil, Annette L. Parks, Brent A. Rupnow, Monique Nicoll, Feng Chen, Lynn M. Young, Mariano Tabios, Kyle A. Edgar, Christopher C. Park, Amanda Norton, Laleh Shayesteh, Pamela M. Carroll
Publikováno v:
Genetics. 170:161-171
Mutations that inactivate the retinoblastoma (Rb) pathway are common in human tumors. Such mutations promote tumor growth by deregulating the G1 cell cycle checkpoint. However, uncontrolled cell cycle progression can also produce new liabilities for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65091c5d6b43aa177e96872e9a4ef058
https://doi.org/10.1534/genetics.104.036343
https://doi.org/10.1534/genetics.104.036343
Autor:
Jennifer E Deal, Geoffrey Duyk, Kyle A. Edgar, Kevin P Bogart, Christopher G. Winter, Matthew A Singer, Daniel Tim Curtis, Robert Fawcett, Lory R Tan, Valentina Vysotskaia, Wesley Y Miyazaki, Casey Kopczynski, Kari Huppert, Marie Marcinko, Elizabeth Howie, Millicent A Winner, Doua Thao, Kellie Whittaker, Nicholas A Dompe, Jonathan Margolis, Deanna Grant, Rachel S. Andrade, Gregory D. Plowman, Marcia Belvin, Mariano Tabios, Megan E Deal-Herr, Helen Francis-Lang, Amanda Norton, Lora Zhao, Stephanie A. Robertson, Annette L. Parks, Lori Friedman, Kenneth J. Shaw, Kevin R. Cook, Keith Killpack, Brett Milash, Thomas C. Kaufman
Publikováno v:
Nature Genetics. 36:288-292
In fruit fly research, chromosomal deletions are indispensable tools for mapping mutations, characterizing alleles and identifying interacting loci. Most widely used deletions were generated by irradiation or chemical mutagenesis. These methods are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477f9bbffc7978d9ed6722537bf31237
https://doi.org/10.1038/ng1312
https://doi.org/10.1038/ng1312
Autor:
Annette L. Parks, Jeffrey S. Nye, Daniel Tim Curtis, Carol S. Himes, Ross Francis, Bing Hai, Jianhuan Zhang, David A. Ruddy, Michael C. Ellis, Richard L. Myers, Ronald Hiebsch, Cara L. Ruble, Javier Apfeld, Jinhe Li, Mark E. Gurney, Mary Sym, Mark E. Maxwell, Garth Joseph Mcgrath, Wei Xu, Monique Nicoll
Publikováno v:
Developmental Cell. 3(1):85-97
Presenilins are components of the gamma-secretase protein complex that mediates intramembranous cleavage of betaAPP and Notch proteins. A C. elegans genetic screen revealed two genes, aph-1 and pen-2, encoding multipass transmembrane proteins, that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f11bca1732c82c37329da15ad8aa1ce
Autor:
Barry Yedvobnick, Hyung Yul Lee, Matthew Ammerman, Annette L. Parks, Marc A. T. Muskavitch, Whitney Helms
Publikováno v:
Developmental Biology. 215:358-374
The phenotypes and genetic interactions associated with mutations in the Drosophila mastermind (mam) gene have implicated it as a component of the Notch signaling pathway. However, its function and site of action within many tissues requiring Notch s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afde3faf6c005006c678f49537201b23
https://doi.org/10.1006/dbio.1999.9477
https://doi.org/10.1006/dbio.1999.9477
Publikováno v:
Mechanisms of Development. 63:61-74
We have examined expression of the neurogenic gene, Delta (Dl), and the regulatory relationships between the Delta-Notch signalling pathway and the proneural gene, achaete, during microchaeta development in Drosophila. Delta is expressed in all micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a21e437b348a37f1eb6ed32034547e
https://doi.org/10.1016/s0925-4773(97)00675-8
https://doi.org/10.1016/s0925-4773(97)00675-8