Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Annette K. Brenner"'
Autor:
Sushma Bartaula-Brevik, Calum Leitch, Maria Hernandez-Valladares, Elise Aasebø, Frode S. Berven, Frode Selheim, Annette K. Brenner, Kristin Paulsen Rye, Marie Hagen, Håkon Reikvam, Emmet McCormack, Øystein Bruserud, Tor Henrik Anderson Tvedt
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 17, p 5546 (2023)
Vacuolar ATPase (V-ATPase) is regarded as a possible target in cancer treatment. It is expressed in primary acute myeloid leukemia cells (AML), but the expression varies between patients and is highest for patients with a favorable prognosis after in
Externí odkaz:
https://doaj.org/article/4201fadf1bac430596919240c14e585a
Autor:
Elise Aasebø, Annette K. Brenner, Maria Hernandez-Valladares, Even Birkeland, Håkon Reikvam, Frode Selheim, Frode S. Berven, Øystein Bruserud
Publikováno v:
Hemato, Vol 2, Iss 3, Pp 607-627 (2021)
In vitro culture is widely used for characterization of primary human acute myeloid leukemia (AML) cells, but even when using optimized handling and culture conditions the AML cells show spontaneous in vitro apoptosis with a gradual decrease in cell
Externí odkaz:
https://doaj.org/article/69f6f55d1b8e44f4821c4839eca80986
Autor:
Annette K. Brenner, Øystein Bruserud
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 12, Pp 1175-1186 (2018)
The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription factors, inflammation, chemota
Externí odkaz:
https://doaj.org/article/55628397400641cbb4bd8ef77bdb2516
Autor:
Elise Aasebø, Annette K. Brenner, Maria Hernandez-Valladares, Even Birkeland, Olav Mjaavatten, Håkon Reikvam, Frode Selheim, Frode S. Berven, Øystein Bruserud
Publikováno v:
Diseases, Vol 9, Iss 4, p 74 (2021)
Acute myeloid leukemia (AML) is an aggressive bone marrow malignancy, and non-leukemic stromal cells (including mesenchymal stem cells, MSCs) are involved in leukemogenesis and show AML-supporting effects. We investigated how constitutive extracellul
Externí odkaz:
https://doaj.org/article/637887ec9a074f4b8d2cebd330cc34f6
Autor:
Annette K. Brenner, Maria W. Gunnes
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1427 (2021)
Neuroblastoma (NBL) is an embryonic malignancy of the sympathetic nervous system and mostly affects children under the age of five. NBL is highly heterogeneous and ranges from spontaneously regressing to highly aggressive disease. One of the risk fac
Externí odkaz:
https://doaj.org/article/1f29d66bdd4a4cb288f2a5eecdce4b87
Autor:
Elise Aasebø, Annette K. Brenner, Maria Hernandez-Valladares, Even Birkeland, Frode S. Berven, Frode Selheim, Øystein Bruserud
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5665 (2021)
Mesenchymal stem cells (MSCs) can differentiate into osteoblasts, and therapeutic targeting of these cells is considered both for malignant and non-malignant diseases. We analyzed global proteomic profiles for osteoblasts derived from ten and MSCs fr
Externí odkaz:
https://doaj.org/article/e363b81bcee34ef0b71a682394c792e3
Autor:
Elise Aasebø, Annette K. Brenner, Even Birkeland, Tor Henrik Anderson Tvedt, Frode Selheim, Frode S. Berven, Øystein Bruserud
Publikováno v:
Cancers, Vol 13, Iss 7, p 1509 (2021)
Extracellular protein release is important both for the formation of extracellular matrix and for communication between cells. We investigated the extracellular protein release by in vitro cultured normal mesenchymal stem cells (MSCs) and by primary
Externí odkaz:
https://doaj.org/article/47c685243bc442a6bc20a7383fabfa69
Autor:
Elise Aasebø, Even Birkeland, Frode Selheim, Frode Berven, Annette K. Brenner, Øystein Bruserud
Publikováno v:
Cancers, Vol 13, Iss 1, p 62 (2020)
Mesenchymal stem cells (MSCs) and osteoblasts are bone marrow stromal cells that contribute to the formation of stem cell niches and support normal hematopoiesis, leukemogenesis and development of metastases from distant cancers. This support is medi
Externí odkaz:
https://doaj.org/article/b1512977bd7d431b895a3460a21987a0
Autor:
Håkon Reikvam, Annette K. Brenner, Karen Marie Hagen, Knut Liseth, Silje Skrede, Kimberley Joanne Hatfield, Øystein Bruserud
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 530-541 (2015)
Interactions between acute myeloid leukemia (AML) blasts and neighboring stromal cells are important for disease development and chemosensitivity. However, the molecular mechanisms involved in the cytokine-mediated crosstalk between mesenchymal stem
Externí odkaz:
https://doaj.org/article/c61cd7b682824ae29c989f9a8eba5eb0
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 18414-18447 (2014)
The cell division cycle 25 (CDC25) phosphatases include CDC25A, CDC25B and CDC25C. These three molecules are important regulators of several steps in the cell cycle, including the activation of various cyclin-dependent kinases (CDKs). CDC25s seem to
Externí odkaz:
https://doaj.org/article/1f68631567744ef5a058fe4a408ae576