Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Annette Hadley"'
Autor:
Kimberly M Ramonell, Wenxiao Zhang, Annette Hadley, Ching-Wen Chen, Katherine T Fay, John D Lyons, Nathan J Klingensmith, Kevin W McConnell, Craig M Coopersmith, Mandy L Ford
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188882 (2017)
Sepsis is a dysregulated systemic response to infection involving many inflammatory pathways and the induction of counter-regulatory anti-inflammatory processes that results in a state of immune incompetence and can lead to multi-organ failure. CXCR4
Externí odkaz:
https://doaj.org/article/d3b27f32140041188bab76e831d6711c
Autor:
Mandy L. Ford, John D. Lyons, Wenxiao Zhang, Annette Hadley, Kimberly M. Ramonell, Kevin W. McConnell, Nathan J. Klingensmith, Craig M. Coopersmith, Ching-Wen Chen, Katherine T. Fay
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188882 (2017)
PLoS ONE
PLoS ONE
Sepsis is a dysregulated systemic response to infection involving many inflammatory pathways and the induction of counter-regulatory anti-inflammatory processes that results in a state of immune incompetence and can lead to multi-organ failure. CXCR4
Autor:
Craig M. Coopersmith, Lindsay M. Margoles, Kimberly M. Ramonell, John D. Lyons, Kevin W. McConnell, Mara A. Serbanescu, Zhe Liang, Annette Hadley, Mandy L. Ford, Rohit Mittal
CD8 T cell loss and dysfunction have been implicated in the increased susceptibility to opportunistic infections during the later immunosuppressive phase of sepsis, but CD8 T cell activation and attrition in early sepsis remain incompletely understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d909a9513addb7eb2a92398dec996e5f
https://europepmc.org/articles/PMC5069090/
https://europepmc.org/articles/PMC5069090/
Autor:
Elizabeth L. Frost, Jarad J. Wilson, Aron E. Lukacher, Todd D. Schell, Annette Hadley, Joshua A. Albrecht, Amelia R. Hofstetter, Christopher D. Pack, Satvir S. Tevethia, Eugene Lin
Publikováno v:
The Journal of Immunology. 188:4340-4348
Repetitive Ag encounter, coupled with dynamic changes in Ag density and inflammation, imparts phenotypic and functional heterogeneity to memory virus-specific CD8 T cells in persistently infected hosts. For herpesvirus infections, which cycle between
Autor:
Amelia R. Hofstetter, Aron E. Lukacher, Jarad J. Wilson, Andrew G. Brooks, Annette Hadley, Lucy C. Sullivan, Mandy L. Ford
Publikováno v:
The Journal of Immunology. 188:3071-3079
We recently identified a protective MHC class Ib-restricted CD8 T cell response to infection with mouse polyomavirus. These CD8 T cells recognize a peptide from aa 139–147 of the VP2 viral capsid protein bound to the nonpolymorphic H-2Q9 molecule,
Autor:
Alyson Swimm, Daniel Kalman, Jarad J. Wilson, Kenneth A. Newell, Aron E. Lukacher, Jun Wang, Ying Dong, Christopher D. Pack, Annette Hadley, Elizabeth L. Frost, Eugene Lin, Cynthia P. Breeden
Publikováno v:
Journal of Virology
Human polyomaviruses are associated with substantial morbidity in immunocompromised patients, including those with HIV/AIDS, recipients of bone marrow and kidney transplants, and individuals receiving immunomodulatory agents for autoimmune and inflam
Autor:
Aron E. Lukacher, Eugene Lin, Annette Hadley, Jarad J. Wilson, Christopher C. Kemball, Christopher D. Pack, Amelia R. Hofstetter
Publikováno v:
The Journal of Immunology. 185:1692-1700
Virus-specific CD4+ T cells optimize antiviral responses by providing help for antiviral humoral responses and CD8+ T cell differentiation. Although CD4+ T cell responses to viral infections that undergo complete clearance have been studied extensive
Autor:
Christopher D. Pack, Phillip A. Swanson, Iwona Stroynowski, Peter E. Jensen, Chyung Ru Wang, Aron E. Lukacher, Annette Hadley
Publikováno v:
The Journal of Experimental Medicine
Although immunity against intracellular pathogens is primarily provided by CD8 T lymphocytes that recognize pathogen-derived peptides presented by major histocompatibility complex (MHC) class Ia molecules, MHC class Ib-restricted CD8 T cells have bee
Publikováno v:
Virology. 358:485-492
CD8 T cells are necessary for controlling tumors induced by mouse polyoma virus (PyV), but the effector mechanism(s) responsible have not been determined. We examined the PyV tumorigenicity in C57BL/6 mice mutated in Fas or carrying targeted disrupti
Autor:
Mandy L. Shawver, Donald Drake, Annette Hadley, Eric A. Butz, Aron E. Lukacher, Charles R. Maliszewski
Publikováno v:
Journal of Virology. 75:544-547
Dendritic cells are pivotal antigen-presenting cells for generating adaptive T-cell responses. Here, we show that dendritic cells belonging to either the myeloid-related or lymphoid-related subset are permissive for infection by mouse polyomavirus an