Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Annette H Erbse"'
Autor:
Minh Chau Nguyen, Hosein Rostamian, Ana Raman, Pengcheng Wei, Dustin C. Becht, Annette H. Erbse, Brianna J. Klein, Tonya M. Gilbert, Gongyi Zhang, M. Andres Blanco, Brian D. Strahl, Sean D. Taverna, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The NuA3 complex is a major regulator of gene transcription and the cell cycle in yeast. Five core subunits are required for complex assembly and function, but it remains unclear how these subunits interact to form the complex. Here, we repo
Externí odkaz:
https://doaj.org/article/b538a1ec84a74287a9d1c58cb505767e
Autor:
Ian R, Fleming, Jonathan P, Hannan, George Hayden, Swisher, Corey D, Tesdahl, Justin G, Martyr, Nicholas J, Cordaro, Annette H, Erbse, Joseph J, Falke
Publikováno v:
Analytical biochemistry. 663
Ras family GTPases (H/K/N-Ras) modulate numerous effectors, including the lipid kinase PI3K (phosphatidylinositol-3-kinase) that generates growth signal lipid PIP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e00da35b47d856082057cc18cd4e3ac
https://pubmed.ncbi.nlm.nih.gov/36526022
https://pubmed.ncbi.nlm.nih.gov/36526022
Autor:
Ian R. Fleming, Jonathan P. Hannan, George Hayden Swisher, Corey D. Tesdahl, Justin G. Martyr, Nicholas J. Cordaro, Annette H. Erbse, Joseph J. Falke
Publikováno v:
Analytical Biochemistry. 663:115019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84401f0ded761136f55b4eaa8ce250a3
https://doi.org/10.1016/j.ab.2022.115019
https://doi.org/10.1016/j.ab.2022.115019
Autor:
G. Hayden Swisher, Justin G. Martyr, Jonathan P. Hannan, Joseph J. Falke, Annette H. Erbse, Nicholas J. Cordaro
Publikováno v:
Anal Biochem
The Ras superfamily of small G proteins play central roles in diverse signaling pathways. Superfamily members act as molecular on-off switches defined by their occupancy with GTP or GDP, respectively. In vitro functional studies require loading with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e28a62c9ae70ec902995fbdfaf1e742
https://europepmc.org/articles/PMC8511091/
https://europepmc.org/articles/PMC8511091/
Autor:
Justin G. Martyr, Joseph J. Falke, G. H. Swisher, Annette H. Erbse, Jonathan P. Hannan, Nicholas J. Cordaro
The Ras superfamily of small G proteins play central roles in diverse signaling pathways. Superfamily members act as molecular on-off switches defined by their occupancy with GTP or GDP, respectively. In vitro functional studies require loading with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09fa3d95b53ef88cad3f8e1b8d20342
https://doi.org/10.1101/2021.06.28.450218
https://doi.org/10.1101/2021.06.28.450218
Autor:
Annette H. Erbse, Pamela N. Dyer, Genevieve H.L. Roberts, Jyothi Mahadevan, Karolin Luger, Uma M. Muthurajan, Johannes Rudolph, Megan Palacio
Publikováno v:
Mol Cell
Poly(ADP-ribose) polymerase 1 (PARP1) is a key player in the response to DNA damage and is the target of four different clinical inhibitors used for the treatment of cancers. Binding of PARP1 to damaged DNA leads to activation via destabilization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9767ef8804175156da01ac37c0ee2a60
https://doi.org/10.1016/j.molcel.2021.11.014
https://doi.org/10.1016/j.molcel.2021.11.014
Autor:
Annette H. Erbse, Nicholas J. Cordaro, Jonathan P. Hannan, G. Hayden Swisher, Joseph J. Falke
Publikováno v:
Anal Biochem
The many members of the Ras superfamily are small GTPases that serve as molecular switches. These proteins bind the guanine nucleotides GTP and GDP with picomolar affinities, thereby stabilizing on- and off-signaling states, respectively. Quantitativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dad985e5b6d0c95414dd319b811e11
https://doi.org/10.1016/j.ab.2020.114066
https://doi.org/10.1016/j.ab.2020.114066
Autor:
Annette H. Erbse, Emily M. Kibby, G. Hayden Swisher, Johnathon H. Hannan, Joseph J. Falke, Justin G. Martyr, Nicholas J. Cordaro
Publikováno v:
Biophysical Journal. 118:282a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2413fa3da5bd537708a0f04761dd50f
https://doi.org/10.1016/j.bpj.2019.11.1610
https://doi.org/10.1016/j.bpj.2019.11.1610
Autor:
Annette H. Erbse, Andrew P. Goodwin, Shambojit Roy, Wounjhang Park, Michael Brasino, Chenchen Mao, Jennifer N. Cha, Liangcan He
Publikováno v:
Journal of the American Chemical Society. 140(37)
A significant challenge for solid tumor treatment is ensuring that a sufficient concentration of therapeutic agent is delivered to the tumor site at doses that can be tolerated by the patient. Biomolecular targeting can bias accumulation in tumors by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421dfc584510d83b22c630ffb3c2beb4
https://pubmed.ncbi.nlm.nih.gov/30203972
https://pubmed.ncbi.nlm.nih.gov/30203972
Publikováno v:
Polym. Chem.. 5:1874-1882
Here, several distinct approaches for photoinitiation and subsequent utilization of the Copper catalyzed azide–alkyne cycloaddition (CuAAC) reaction are developed. In particular, Cu(II)–ligand complexes were synthesized that enabled direct photor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f4ed546c58c661e4db1778948cddc6
https://doi.org/10.1039/c3py01064c
https://doi.org/10.1039/c3py01064c